公开(公告)号：US10571456B2

公开(公告)日：2020-02-25

申请号：US15323745

申请日：2015-06-02

Applicant: SONY CORPORATION

Inventor： Yoichi Katsumoto ,  Marcaurele Brun ,  Yoshihito Hayashi

IPC: G01N33/49 ,  G01N27/06 ,  C12Q1/00

Abstract: Provided is an electrical measuring cartridge including at least: a biological sample holding section that accommodates a liquid biological sample containing a sedimenting component; a measuring electrode unit that is fixed to the biological sample holding section and composed of a pair of electrodes for electrically measuring a state of the biological sample; and a sedimentation measuring electrode unit that is fixed to a position at a different height from the measuring electrode unit of the biological sample holding section and composed of a pair of electrodes for electrically measuring a degree of sedimentation of the sedimenting component.

公开(公告)号：US10466257B2

公开(公告)日：2019-11-05

申请号：US14095657

申请日：2013-12-03

Applicant: Sony Corporation

Inventor： Yoichi Katsumoto ,  Marcaurele Brun ,  Yoshihito Hayashi

IPC: G01N27/02 ,  G01N33/86 ,  G01N33/49

Abstract: There is provided an electrical measuring container of a biological sample in a liquid phase, including at least a biological sample holding section configured to accommodate a biological sample in a liquid phase and made of a resin, and an electrical conductive section fixed to the biological sample holding section. In a state in which a portion of the electrical conductive section is buried in the biological sample holding section, the biological sample holding section and the electrical conductive section are integrally formed with each other.

公开(公告)号：US20190101526A1

公开(公告)日：2019-04-04

申请号：US16086943

申请日：2016-12-27

Applicant: Sony Corporation

Inventor： Marcaurele Brun ,  Yoshihito Hayashi

IPC: G01N33/49 ,  G01N27/02 ,  G01N33/86

Abstract: The main object of the present technology is to provide a technology capable of acquiring, in a single measurement, a plurality of pieces of information related to fibrinogen, when measuring the electrical characteristics of a blood sample.In view of the above, the present technology provides a blood state analysis apparatus including at least an analysis unit that uses data related to the temporal change in electrical characteristics to analyze information related to fibrinogen in a blood sample, in which the analysis unit uses at least two predetermined time points derived from the data related to the temporal change on a basis of a predetermined mathematical definition to calculate a parameter R, and acquires at least two pieces of information related to the fibrinogen in the blood sample.

公开(公告)号：US20190041379A1

公开(公告)日：2019-02-07

申请号：US16074587

申请日：2016-11-14

Applicant: Sony Corporation

Inventor： Kenzo Machida ,  Shinji Omori ,  Yoshihito Hayashi ,  Marcaurele Brun

IPC: G01N33/49 ,  G01N27/12 ,  G01N33/86

Abstract: To provide a technique which is useful in verification of measurement accuracy before measurement in the measurement of electric characteristics of a blood sample.There is provided a sample for measurement of electric characteristics at least including a liquid containing a blood coagulation factor, and micro particles. The density of each of the micro particles is different from the density of the liquid containing the blood coagulation factor. In addition, there is provided an electric characteristic measuring apparatus and an electric characteristic measuring method as well each using the sample for measurement of electric characteristics.

公开(公告)号：US20160282366A1

公开(公告)日：2016-09-29

申请号：US14778277

申请日：2014-02-18

Applicant: SONY CORPORATION

Inventor： Yoshihito Hayashi ,  Yoichi Katsumoto ,  Marcaurele Brun

IPC: G01N33/86 ,  G01N27/02

CPC classification number: G01N33/86 ,  G01N27/026 ,  G01N33/4905

Abstract: A blood state evaluation device, blood state evaluation system, blood state evaluation method, and program that enable evaluation of the risk of thrombosis easily and precisely is provided. An electrical characteristic of blood being an evaluation target is chronologically measured in two or more frequencies or two or more frequency bands. On the basis of chronological change data of the measured electrical characteristic of the blood, a state of blood is evaluated.

Abstract translation: 提供了能够容易且精确地评价血栓形成风险的血液状态评价装置，血液状态评价系统，血液状态评价方法和程序。 以两个或更多个频率或两个或更多个频带按时间顺序测量作为评估目标的血液的电特性。 根据测定的血液电特性的时间顺序变化数据，对血液的状态进行评价。

公开(公告)号：US08999243B2

公开(公告)日：2015-04-07

申请号：US14201051

申请日：2014-03-07

Applicant: Sony Corporation

Inventor： Yoshihito Hayashi ,  MarcAurele Brun ,  Shinji Omori ,  Yoichi Katsumoto ,  Kazumasa Sato

IPC: G01N33/86 ,  G01N33/48 ,  G01N33/49 ,  G01N27/22

CPC classification number: G01N33/86 ,  G01N27/221 ,  G01N33/4905

Abstract: A blood coagulation analysis device and method in which information relating to the coagulability of blood is evaluated based on a change generated in a permittivity measured in a coagulation process of the blood due to addition of a substance that activates or inactivates platelets to the blood.

Abstract translation: 一种血液凝固分析装置和方法，其中基于由于将血小板活化或灭活的物质添加到血液中而在血液的凝固过程中测量的介电常数产生的变化来评估与血液的凝固性有关的信息。

公开(公告)号：US11982667B2

公开(公告)日：2024-05-14

申请号：US17286074

申请日：2019-08-27

Applicant: SONY CORPORATION

Inventor： Aya Fuchigami ,  Seungmin Lee ,  Yoshihito Hayashi ,  Kenzo Machida

IPC: G01N33/49 ,  G01N27/22 ,  G01N33/50

CPC classification number: G01N33/4905 ,  G01N27/221 ,  G01N33/5044

Abstract: Provided is a platelet aggregation capacity analyzer including a blood coagulation system-analyzing unit that analyzes a platelet aggregation capacity based on measurement data during a coagulation process of a platelet-containing sample, and an output control unit that controls an output of results analyzed by the blood coagulation system-analyzing unit, in which the blood coagulation system-analyzing unit analyzes the platelet aggregation capacity of the platelet-containing sample based on the barb of measurement data during the coagulation process with a platelet aggregation inhibitor added to the platelet-containing sample and measurement data during the coagulation process without a platelet agonist or the platelet aggregation inhibitor added to the platelet-containing sample.

公开(公告)号：US20210263052A1

公开(公告)日：2021-08-26

申请号：US17260969

申请日：2019-06-12

Applicant: Sony Corporation

Inventor： Yoshihito Hayashi ,  Tokujiro Uchida ,  Yudai Yamamoto

IPC: G01N33/86 ,  G01N27/22

Abstract: To provide a blood coagulation system analysis device capable of easily and rapidly evaluating a human tissue factor pathway inhibitor.
A blood coagulation system analysis device provided with a pair of electrodes, an application unit that applies an alternating voltage to the pair of electrodes at a predetermined time interval, a measurement unit that measures complex permittivity of a blood sample arranged between the pair of electrodes, and an analysis unit that evaluates a human tissue factor pathway inhibitor (TFPI) on the basis of the complex permittivity at a specific frequency in a predetermined period measured at the time interval after anticoagulant action acting on the blood sample is released.

公开(公告)号：US10989722B2

公开(公告)日：2021-04-27

申请号：US16566039

申请日：2019-09-10

Applicant: SONY CORPORATION

Inventor： Yoichi Katsumoto ,  Marcaurele Brun ,  Yoshihito Hayashi

IPC: G01N33/86 ,  G01N33/49 ,  G01N27/02 ,  G01R27/26

Abstract: There is provided an electrical measuring container of a biological sample in a liquid phase, including at least a biological sample holding section that accommodates a biological sample in a liquid phase and made of a resin, and an electrical conductive section fixed to the biological sample holding section. In a state in which a portion of the electrical conductive section is buried in the biological sample holding section, the biological sample holding section and the electrical conductive section are integrally formed with each other.

公开(公告)号：US10648936B2

公开(公告)日：2020-05-12

申请号：US14772550

申请日：2014-02-20

Applicant: Sony Corporation

Inventor： Yoshihito Hayashi ,  Marcaurele Brun ,  Yoichi Katsumoto

IPC: G01N27/00 ,  G01N27/02 ,  G01N33/49 ,  G01N27/22 ,  G01N15/05

Abstract: There is provided a blood condition analyzing device including an erythrocyte quantitative evaluation unit configured to evaluate a hematocrit value and/or a hemoglobin amount on the basis of an electrical characteristic of a blood sample at a frequency of 2 to 25 MHz.