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公开(公告)号:US20200375516A1
公开(公告)日:2020-12-03
申请号:US16999213
申请日:2020-08-21
Applicant: SteadyMed Ltd.
Inventor: Jonathan Goldstein , Niles Fleischer , Nir Rotem , Lior Bar-Gat , Vladimir Piskosh
Abstract: A displacement-generating battery cell for driving a drug-delivery device is described. The cell may include at least one volume-changing element. The cell may include a housing formed according to a concertina-shaped design with folds in the walls thereof and may contain an internal chemical reaction system. The chemical reaction system may include an electrode. The electrode may be the volume-changing element. The arrangement of said chemical reaction system may be such that an expansion of the volume-changing element in a direction lengthens the cell and thus reduces the extent of the folds. Drug-delivery devices including the displacement-generating battery cell are also described.
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公开(公告)号:US20200368425A1
公开(公告)日:2020-11-26
申请号:US16986544
申请日:2020-08-06
Applicant: SteadyMed Ltd.
Inventor: Amir Genosar , Doron Aurbach , Elena Markevich , Grigory Salitra , Jonathan Goldstein , Mikhail Levi , Niles Fleischer , Yehuda Bachar , Yossi Aldar
Abstract: The present application provides a self-powered drug-delivery device. The device includes a chamber having a wall. The chamber contains a fluid and is in connection with an administration means. The device also includes a displacement-generating battery cell. The device further includes an electrically-controlled battery unit, which includes the displacement-generating battery cell coupled to the chamber by a coupling means. The displacement-generating battery cell includes an element that changes shape as a result of charge or discharge of the battery cell so as to cause a displacement within the battery unit. The arrangement of the battery unit, the coupling means, the wall, the chamber, and the administration means is such that the displacement derived from the battery unit is conveyed by the coupling means to cause displacement of the wall of the chamber such that the fluid is expelled from the chamber to force a drug towards the administration means.
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公开(公告)号:US20190060563A1
公开(公告)日:2019-02-28
申请号:US16173069
申请日:2018-10-29
Applicant: SteadyMed, Ltd.
Inventor: Nir Rotem , Keren Fradkin , Jonathan Goldstein
Abstract: A drug-delivery device comprising a drug-reservoir assembly, displacement-generating actuator, and drug administration unit is described, wherein the drug-reservoir assembly comprises at least one flexible wall and a constraining ring, such that the displacement generated by the actuator collapses a flexible wall of the assembly expelling the drug contents of the drug-reservoir towards said drug administration means.
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公开(公告)号:US20180250465A1
公开(公告)日:2018-09-06
申请号:US15972322
申请日:2018-05-07
Applicant: SteadyMed Ltd.
Inventor: Amir Genosar , Doron Aurbach , Elena Markevich , Grigory Salitra , Jonathan Goldstein , Mikhail Levi , Niles Fleischer , Yehuda Bachar , Yossi Aldar
CPC classification number: A61M5/145 , A61M5/14248 , A61M5/14276 , A61M5/1452 , A61M5/14586 , A61M5/172 , A61M5/1723 , A61M5/2046 , A61M2005/14204 , A61M2005/14252 , A61M2005/14513 , A61M2205/35 , A61M2205/8206 , A61M2230/201 , H01M2/02 , H01M10/02 , H01M10/05 , H01M10/42 , H01M2220/30
Abstract: The present application provides a self-powered drug-delivery device. The device includes a chamber having a wall. The chamber contains a fluid and is in connection with an administration means. The device also includes a displacement-generating battery cell. The device further includes an electrically-controlled battery unit, which includes the displacement-generating battery cell coupled to the chamber by a coupling means. The displacement-generating battery cell includes an element that changes shape as a result of charge or discharge of the battery cell so as to cause a displacement within the battery unit. The arrangement of the battery unit, the coupling means, the wall, the chamber, and the administration means is such that the displacement derived from the battery unit is conveyed by the coupling means to cause displacement of the wall of the chamber such that the fluid is expelled from the chamber to force a drug towards the administration means.
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公开(公告)号:US20180035935A1
公开(公告)日:2018-02-08
申请号:US15634880
申请日:2017-06-27
Applicant: SteadyMed Ltd.
Inventor: Jonathan Goldstein , Niles Fleischer , Nir Rotem , Lior Bar-Gat , Vladimir Piskosh
Abstract: Embodiments of the present invention provide drug-delivery devices comprising a drug reservoir chamber containing a substance to be delivered, in fluid connection with a drug administration means, and at least one displacement-generating battery cell coupled to said drug reservoir chamber by a coupling means, the at least one displacement-generating battery cell comprising an element that changes shape as a result of discharge of the battery cell so as to cause a displacement within the battery unit, the arrangement being such that the displacement derived from said battery unit is conveyed by said coupling means to cause displacement of at least a portion of a wall of said drug reservoir chamber reducing the volume of said drug reservoir chamber such that said substance is expelled from said drug reservoir chamber towards said drug administration means upon discharge, thereby being a self-powered drug delivery device.
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公开(公告)号:US10750987B2
公开(公告)日:2020-08-25
申请号:US15634880
申请日:2017-06-27
Applicant: SteadyMed Ltd.
Inventor: Jonathan Goldstein , Niles Fleischer , Nir Rotem , Lior Bar-Gat , Vladimir Piskosh
Abstract: Embodiments of the present invention provide drug-delivery devices comprising a drug reservoir chamber containing a substance to be delivered, in fluid connection with a drug administration means, and at least one displacement-generating battery cell coupled to said drug reservoir chamber by a coupling means, the at least one displacement-generating battery cell comprising an element that changes shape as a result of discharge of the battery cell so as to cause a displacement within the battery unit, the arrangement being such that the displacement derived from said battery unit is conveyed by said coupling means to cause displacement of at least a portion of a wall of said drug reservoir chamber reducing the volume of said drug reservoir chamber such that said substance is expelled from said drug reservoir chamber towards said drug administration means upon discharge, thereby being a self-powered drug delivery device.
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公开(公告)号:US10737017B2
公开(公告)日:2020-08-11
申请号:US15972322
申请日:2018-05-07
Applicant: SteadyMed Ltd.
Inventor: Amir Genosar , Doron Aurbach , Elena Markevich , Grigory Salitra , Jonathan Goldstein , Mikhail Levi , Niles Fleischer , Yehuda Bachar , Yossi Aldar
Abstract: The present application provides a self-powered drug-delivery device. The device includes a chamber having a wall. The chamber contains a fluid and is in connection with an administration means. The device also includes a displacement-generating battery cell. The device further includes an electrically-controlled battery unit, which includes the displacement-generating battery cell coupled to the chamber by a coupling means. The displacement-generating battery cell includes an element that changes shape as a result of charge or discharge of the battery cell so as to cause a displacement within the battery unit. The arrangement of the battery unit, the coupling means, the wall, the chamber, and the administration means is such that the displacement derived from the battery unit is conveyed by the coupling means to cause displacement of the wall of the chamber such that the fluid is expelled from the chamber to force a drug towards the administration means.
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公开(公告)号:US09687186B2
公开(公告)日:2017-06-27
申请号:US13956965
申请日:2013-08-01
Applicant: SteadyMed Ltd.
Inventor: Jonathan Goldstein , Niles Fleischer , Nir Rotem , Lior Bar-Gat , Vladimir Piskosh
CPC classification number: A61B5/157 , A61B5/15003 , A61B5/150992 , A61M5/1452 , A61M5/14526 , A61M2005/14204
Abstract: Embodiments of the present invention provide drug-delivery devices comprising a drug reservoir chamber containing a substance to be delivered, in fluid connection with a drug administration means, and at least one displacement-generating battery cell coupled to said drug reservoir chamber by a coupling means, the at least one displacement-generating battery cell comprising an element that changes shape as a result of discharge of the battery cell so as to cause a displacement within the battery unit, the arrangement being such that the displacement derived from said battery unit is conveyed by said coupling means to cause displacement of at least a portion of a wall of said drug reservoir chamber reducing the volume of said drug reservoir chamber such that said substance is expelled from said drug reservoir chamber towards said drug administration means upon discharge, thereby being a self-powered drug delivery device.
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公开(公告)号:US20150017493A1
公开(公告)日:2015-01-15
申请号:US14456416
申请日:2014-08-11
Applicant: SteadyMed Ltd.
Inventor: Amir Genosar , Doron Aurbach , Elena Markevich , Grigory Salitra , Jonathan Goldstein , Mikhail Levi , Niles Fleischer , Yehuda Bachar , Yossi Aldar
CPC classification number: A61M5/145 , A61M5/14248 , A61M5/14276 , A61M5/1452 , A61M5/14586 , A61M5/172 , A61M5/1723 , A61M5/2046 , A61M2005/14204 , A61M2005/14252 , A61M2005/14513 , A61M2205/35 , A61M2205/8206 , A61M2230/201 , H01M2/02 , H01M10/02 , H01M10/05 , H01M10/42 , H01M2220/30
Abstract: The present application provides a drug-delivery device comprising a drug reservoir chamber 16, containing a substance to be delivered, in fluid connection with a drug administration means 18, and an electrically-controlled battery unit 10 comprising at least one displacement-generating battery cell 19 coupled to the drug reservoir chamber 16 by a coupling means 14, the arrangement being such that the displacement derived from the battery unit 10 is conveyed by the coupling means 14 to the drug reservoir chamber 16 such that the substance is expelled from the drug reservoir chamber 16 towards the drug administration means 18.
Abstract translation: 本申请提供了一种药物递送装置,其包括药物储存室16,其包含与药物施用装置18流体连接的待递送物质,以及电控电池单元10,其包括至少一个位移产生电池单元 19通过联接装置14耦合到药物储存室16,该布置使得从电池单元10获得的位移被耦合装置14输送到药物储存室16,使得物质从药物储存器中排出 腔室16朝向药物管理装置18。
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公开(公告)号:US10010671B2
公开(公告)日:2018-07-03
申请号:US14456416
申请日:2014-08-11
Applicant: SteadyMed Ltd.
Inventor: Amir Genosar , Doron Aurbach , Elena Markevich , Grigory Salitra , Jonathan Goldstein , Mikhail Levi , Niles Fleischer , Yehuda Bachar , Yossi Aldar
IPC: A61M5/14 , A61M5/145 , A61M5/142 , A61M5/20 , A61M5/172 , H01M2/02 , H01M10/02 , H01M10/05 , H01M10/42
CPC classification number: A61M5/145 , A61M5/14248 , A61M5/14276 , A61M5/1452 , A61M5/14586 , A61M5/172 , A61M5/1723 , A61M5/2046 , A61M2005/14204 , A61M2005/14252 , A61M2005/14513 , A61M2205/35 , A61M2205/8206 , A61M2230/201 , H01M2/02 , H01M10/02 , H01M10/05 , H01M10/42 , H01M2220/30
Abstract: Embodiments include a displacement-generating battery cell for driving a drug-delivery device. The cell includes at least one volume-changing element. The cell also includes a housing formed according to a concertina-shaped design with folds in the walls thereof and containing an internal chemical reaction system. The arrangement of the chemical reaction system is such that as the cell is discharged, the volume-changing element expands, thereby lengthening the battery and thus reducing the extent of said folds, such that the cell becomes taller to reflect the expansion of the volume-changing component.
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