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公开(公告)号：US20200375516A1
公开(公告)日：2020-12-03
申请号：US16999213
申请日：2020-08-21
Applicant: SteadyMed Ltd.
Inventor： Jonathan Goldstein , Niles Fleischer , Nir Rotem , Lior Bar-Gat , Vladimir Piskosh
Abstract: A displacement-generating battery cell for driving a drug-delivery device is described. The cell may include at least one volume-changing element. The cell may include a housing formed according to a concertina-shaped design with folds in the walls thereof and may contain an internal chemical reaction system. The chemical reaction system may include an electrode. The electrode may be the volume-changing element. The arrangement of said chemical reaction system may be such that an expansion of the volume-changing element in a direction lengthens the cell and thus reduces the extent of the folds. Drug-delivery devices including the displacement-generating battery cell are also described.
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公开(公告)号：US20200368425A1
公开(公告)日：2020-11-26
申请号：US16986544
申请日：2020-08-06
Applicant: SteadyMed Ltd.
Inventor： Amir Genosar , Doron Aurbach , Elena Markevich , Grigory Salitra , Jonathan Goldstein , Mikhail Levi , Niles Fleischer , Yehuda Bachar , Yossi Aldar
Abstract: The present application provides a self-powered drug-delivery device. The device includes a chamber having a wall. The chamber contains a fluid and is in connection with an administration means. The device also includes a displacement-generating battery cell. The device further includes an electrically-controlled battery unit, which includes the displacement-generating battery cell coupled to the chamber by a coupling means. The displacement-generating battery cell includes an element that changes shape as a result of charge or discharge of the battery cell so as to cause a displacement within the battery unit. The arrangement of the battery unit, the coupling means, the wall, the chamber, and the administration means is such that the displacement derived from the battery unit is conveyed by the coupling means to cause displacement of the wall of the chamber such that the fluid is expelled from the chamber to force a drug towards the administration means.
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公开(公告)号：US10463847B2
公开(公告)日：2019-11-05
申请号：US14737204
申请日：2015-06-11
Applicant: STEADYMED LTD.
Inventor： Assaf Shaked , Inna Dekel , Jonathan Guillaume Jamin , Stephen Edward Augustyn , Stewart Maddison Fox , Peter Noymer
Abstract: An exemplary infusion set includes a tubing, a first connector, and a second connector. The first connector connects a first terminus of the tubing to an exit port of an infusion pump, providing fluid communication between fluid being conveyed by the infusion pump and the tubing. The second connector connects a second terminus of the tubing to a delivery module, providing fluid communication between the tubing and the delivery module. Full engagement of the first connector and the exit port of the infusion pump actuates operation of the infusion pump.
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公开(公告)号：US11013855B2
公开(公告)日：2021-05-25
申请号：US16377992
申请日：2019-04-08
Applicant: SteadyMed Ltd.
Inventor： Nir Rotem
Abstract: Embodiments may include a method of delivering a drug. The method may include removing or releasing a structure from a patch-pump assembly. The patch-pump assembly may include a sealed prefilled drug-reservoir, a fluid passageway, a cannula-containing assembly, and a penetrator. The method may also include penetrating the sealed prefilled drug-reservoir containing the drug to establish fluid communication between the sealed prefilled drug-reservoir and a fluid passageway by removing or releasing the structure. The method may further include flowing the drug from the prefilled drug-reservoir to the fluid passageway. In addition, the method may include flowing the drug from the fluid passageway to a cannula-containing assembly. Furthermore, the method may include delivering the drug subcutaneously to a subject using the cannula-containing assembly.
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公开(公告)号：US20190060563A1
公开(公告)日：2019-02-28
申请号：US16173069
申请日：2018-10-29
Applicant: SteadyMed, Ltd.
Inventor： Nir Rotem , Keren Fradkin , Jonathan Goldstein
Abstract: A drug-delivery device comprising a drug-reservoir assembly, displacement-generating actuator, and drug administration unit is described, wherein the drug-reservoir assembly comprises at least one flexible wall and a constraining ring, such that the displacement generated by the actuator collapses a flexible wall of the assembly expelling the drug contents of the drug-reservoir towards said drug administration means.
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Patent Agency Ranking
公开(公告)号：US10071209B2
公开(公告)日：2018-09-11
申请号：US14384131
申请日：2013-03-11
Applicant: SteadyMed Ltd.
Inventor： Ian Solomon , Jacob Rand , Jonathan Rigby
CPC classification number: A61M5/422 , A61M5/14248 , A61N1/0456 , A61N1/0476 , A61N1/0492 , A61N1/36021
Abstract: The present invention provides an infusion-patch comprising; a cannula; a base; at least one adhesive region in said base suitable for skin attachment; at least one skin-access area within said base; and at least one conduit in fluid connection with said at least one skin access area, wherein said at least one conduit in fluid connection with said at least one skin access area facilitates the transfer of an anesthetic substance within at least a first anesthetic-reservoir which may be removably attached and in fluid connection with said at least one contact area, promoting delivery of said anesthetic substance to said at least one skin-access areas, and wherein said anesthetic substance delivered to said skin-access areas may be at least partially replenished without removing said infusion-patch.
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公开(公告)号：US20170304532A1
公开(公告)日：2017-10-26
申请号：US15605420
申请日：2017-05-25
Applicant: SteadyMed Ltd.
Inventor： Nir Rotem
CPC classification number: A61M5/14248 , A61M5/145 , A61M5/158 , A61M5/1626 , A61M2005/14252 , A61M2005/1585 , F04C2270/041
Abstract: Embodiments may include a method of delivering a drug. The method may include removing or releasing a structure from a patch-pump assembly. The patch-pump assembly may include a sealed prefilled drug-reservoir, a fluid passageway, a cannula-containing assembly, and a penetrator. The method may also include penetrating the sealed prefilled drug-reservoir containing the drug to establish fluid communication between the sealed prefilled drug-reservoir and a fluid passageway by removing or releasing the structure. The method may further include flowing the drug from the prefilled drug-reservoir to the fluid passageway. In addition, the method may include flowing the drug from the fluid passageway to a cannula-containing assembly. Furthermore, the method may include delivering the drug subcutaneously to a subject using the cannula-containing assembly.
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公开(公告)号：US20160361491A1
公开(公告)日：2016-12-15
申请号：US14737204
申请日：2015-06-11
Applicant: STEADYMED LTD.
Inventor： Assaf Shaked , Inna Dekel , Jon Guillaume Jamin , Stephen Edward Augustyn , Stewart Maddison Fox , Peter Noymer
Abstract: An exemplary infusion set includes a tubing, a first connector, and a second connector. The first connector connects a first terminus of the tubing to an exit port of an infusion pump, providing fluid communication between fluid being conveyed by the infusion pump and the tubing. The second connector connects a second terminus of the tubing to a delivery module, providing fluid communication between the tubing and the delivery module. Full engagement of the first connector and the exit port of the infusion pump actuates operation of the infusion pump.
Abstract translation: 示例性输液器包括管道，第一连接器和第二连接器。 第一连接器将管道的第一末端连接到输注泵的出口，从而提供由输注泵输送的流体与管道之间的流体连通。 第二连接器将管道的第二端连接到输送模块，从而在管道和输送模块之间提供流体连通。 输液泵的第一连接器和出口的完全接合致动输液泵的操作。
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公开(公告)号：US20150045718A1
公开(公告)日：2015-02-12
申请号：US14384131
申请日：2013-03-11
Applicant: SteadyMed Ltd.
Inventor： Ian Shlomo , Jacob Rand , Jonathan Rigby
CPC classification number: A61M5/422 , A61M5/14248 , A61N1/0456 , A61N1/0476 , A61N1/0492 , A61N1/36021
Abstract: The present invention provides an infusion-patch comprising; a cannula; a base; at least one adhesive region in said base suitable for skin attachment; at least one skin-access area within said base; and at least one conduit in fluid connection with said at least one skin access area, wherein said at least one conduit in fluid connection with said at least one skin access area facilitates the transfer of an anesthetic substance within at least a first anesthetic-reservoir which may be removably attached and in fluid connection with said at least one contact area, promoting delivery of said anesthetic substance to said at least one skin-access areas, and wherein said anesthetic substance delivered to said skin-access areas may be at least partially replenished without removing said in fusion-patch.
Abstract translation: 本发明提供了一种灌注补片，其包括： 套管 一个基地 所述基底中的至少一个粘合剂区域适于皮肤附着; 所述基座内的至少一个皮肤接近区域; 以及至少一个与所述至少一个皮肤接近区域流体连接的导管，其中与所述至少一个皮肤接近区域流体连接的所述至少一个导管便于在至少第一麻醉容器内的麻醉物质的转移 可以可移除地附接并与所述至少一个接触区域流体连接，促进所述麻醉物质递送到所述至少一个皮肤接近区域，并且其中输送到所述皮肤接近区域的所述麻醉物质可以至少部分补充 没有在融合贴片中去除。
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公开(公告)号：US20200054754A1
公开(公告)日：2020-02-20
申请号：US16609544
申请日：2018-05-10
Applicant: SteadyMed Ltd.
Inventor： Michael Laird Hurrey , Drazen Ostovic , Peter Noymer
IPC: A61K47/12 , A61K47/02 , A61P23/02 , A61K31/445
Abstract: This invention describes compositions comprising at least 75 mg/mL of solubilized otherwise poorly soluble drug in an aqueous environment, wherein the composition further comprises a combination of 3 or more acids. Methods of providing analgesia, anti-pyretic effects or reducing pain in a subject presenting with a pain condition, and methods of reducing administration site irritation, inflammation or a combination thereof in a subject presenting with a pain condition, comprising the steps of administering such compositions and infusion pumps containing such compositions are also described.
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