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公开(公告)号：US20150140562A1
公开(公告)日：2015-05-21
申请号：US14543160
申请日：2014-11-17
CPC分类号： C12Q1/6851 , B01L3/50851 , B01L7/52 , B01L2200/10 , B01L2200/12 , B01L2300/0816 , B01L2300/0819 , B01L2300/0829 , B01L2300/0851 , B01L2300/0887 , B01L2300/0893 , B01L2300/161 , B01L2300/163 , B01L2300/168 , B01L2300/1827 , C12Q1/6825 , C12Q1/686 , G01N21/01 , G01N21/0303 , G01N21/253 , G01N21/51 , G01N21/6452 , G06K9/0014 , G06T7/0012 , G06T7/0014 , G06T2207/10064 , G06T2207/20024 , G06T2207/20061 , G06T2207/30072 , Y10T29/49885
摘要： An optical analyzer, configured to receiving a cartridge for biochemical analyses including a plurality of wells, and carrying out fluorescence analysis of the cartridge, in particular of the wells. The analyzer comprises a control unit (microprocessor and memory) configured to: (a) acquiring an image associated to the fluorescence emitted by the cartridge; (b) identifying, in the image, pixels belonging to boundary lines of the wells by generating a black and white binary image; (c) recognizing, between the geometrical shapes identified in step (b), the ones that best approximate a reference geometrical shape identifying an ideal well; (d) acquiring, from the starting image, values of light intensity only in portions of the image itself that in turn correspond to the regions recognized in step (c); and (e) evaluating a state of advance and/or a result of the biochemical analysis on the basis of the values of light intensity acquired in step (d).
摘要翻译： 一种光学分析器，被配置为接收用于包括多个孔的生化分析的盒，并且对所述盒，特别是所述孔进行荧光分析。 分析器包括控制单元（微处理器和存储器），其被配置为：（a）获取与由盒发出的荧光相关联的图像; （b）通过生成黑白二进制图像在图像中识别属于孔的边界线的像素; （c）在步骤（b）中识别的几何形状之间识别最接近标识理想井的参考几何形状的几何形状; （d）仅在图像本身的部分中从起始图像获取光强值，其依次对应于步骤（c）中识别的区域; 和（e）基于步骤（d）中获得的光强度的值来评估生化分析的进展状态和/或生化分析结果。
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公开(公告)号：US20150140563A1
公开(公告)日：2015-05-21
申请号：US14543276
申请日：2014-11-17
CPC分类号： C12Q1/6851 , B01L3/50851 , B01L7/52 , B01L2200/10 , B01L2200/12 , B01L2300/0816 , B01L2300/0819 , B01L2300/0829 , B01L2300/0851 , B01L2300/0887 , B01L2300/0893 , B01L2300/161 , B01L2300/163 , B01L2300/168 , B01L2300/1827 , C12Q1/6825 , C12Q1/686 , G01N21/01 , G01N21/0303 , G01N21/253 , G01N21/51 , G01N21/6452 , G06K9/0014 , G06T7/0012 , G06T7/0014 , G06T2207/10064 , G06T2207/20024 , G06T2207/20061 , G06T2207/30072 , Y10T29/49885
摘要： A cartridge for an optical analysis, including a supporting body, having a first face and a second face opposite to one another; a plurality of wells adapted to receive a biological solution to be analyzed, the wells extending in the supporting body on the first face; at least one biocompatible layer extending inside each well; an anti-reflection layer extending on the first face outside the wells; and a reflection layer extending inside each well. Methods of using same are also provided.
摘要翻译： 一种用于光学分析的盒，包括支撑体，具有彼此相对的第一面和第二面; 适于接收要分析的生物溶液的多个井，所述井在所述第一面上的所述支撑体中延伸; 在每个孔内延伸的至少一个生物相容层; 在所述孔的外部的所述第一面上延伸的防反射层; 以及在每个孔内延伸的反射层。 还提供了使用方法。
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