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公开(公告)号:US20190216770A1
公开(公告)日:2019-07-18
申请号:US16248921
申请日:2019-01-16
Applicant: Symrise AG
Inventor: Elke Köck , Jakob Ley , Veronika Somoza , Kathrin Liszt , Sabine Widder
IPC: A61K31/365 , A61K31/353 , A23F3/40 , A61K31/341 , A23F5/46 , G01N33/50 , A23L2/52 , A61K47/22 , A23L27/00 , A23L33/10
CPC classification number: A61K31/365 , A23F3/405 , A23F5/465 , A23L2/52 , A23L27/86 , A23L33/10 , A23V2002/00 , A61K9/0056 , A61K9/0058 , A61K9/0095 , A61K9/19 , A61K9/4875 , A61K31/341 , A61K31/353 , A61K47/22 , G01N33/5044
Abstract: Pharmaceutical preparations are proposed, comprising bitter-masking acting substances for reducing and/or inhibiting gastric acid secretion induced by food constituents.
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公开(公告)号:US09468225B2
公开(公告)日:2016-10-18
申请号:US14179170
申请日:2014-02-12
Applicant: Symrise AG
Inventor: Jakob Ley , Sabine Widder , Veronika Somoza , Barbara Rohm , Matthias Zaunschirm , Gerhard Krammer
IPC: A61K31/16 , A61K31/164 , A23K20/105 , A23K1/16 , A23L1/29 , A23L1/30
CPC classification number: A23K20/105 , A23L33/10 , A23L33/30 , A61K31/16 , A61K31/164
Abstract: Suggested are new compositions for oral ingestion, comprising at least one active agent from the group of alkamides. The compositions which are orally ingested reduce the uptake of free fatty acids in the adipocytes and at the same time stimulate the release of serotonin and dopamine, which leads to a reduction of appetite, a feeling of satiety and a positive mood. In doing so, the new compositions are thus perfectly suitable to counteract any undesired gain of weight.
Abstract translation: 建议的是用于口服摄取的新组合物,其包含至少一种来自该组烷酰胺的活性剂。 口服摄入的组合物降低脂肪细胞中游离脂肪酸的摄取量,同时刺激5-羟色胺和多巴胺的释放,这导致食欲降低,饱腹感和积极情绪。 因此,新组合物非常适合抵消任何不希望的重量增益。
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公开(公告)号:US10813378B2
公开(公告)日:2020-10-27
申请号:US15310191
申请日:2015-06-03
Applicant: SYMRISE AG
Inventor: Sabine Widder , Kathrin Langer , Gerhard Krammer , Olga Pauli , Cornelia Homner
IPC: A23L33/17 , A23L29/262 , A23L27/00 , A23L33/175 , A23L33/105
Abstract: The invention relates to substance mixtures which contain (a) sodium carboxymethyl cellulose and (b) at least one bitter principle selected from the group consisting of xanthines, phenolic glycosides, flavanoid glycosides, hydrolysable or non-hydrolysable tannins, flavones and the glycosides thereof, caffeic acid and the esters thereof, terpenoid bitter principles, catechin, epicatechin, epigallocatechin, gallocatechin, gallocatechin-3-gallate, leucine, isoleucine, valine, tryptophan and phenylalanine, protein hydrolysates, peptides and metal salts and their mixtures, and optionally (c) dextrins, with the proviso that the components (a) and (b) are in the weight ratio of from 1:1 to 1:1,000.
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公开(公告)号:US20210330641A1
公开(公告)日:2021-10-28
申请号:US17339183
申请日:2021-06-04
Applicant: Symrise AG
Inventor: Elke Köck , Jakob Ley , Veronika Somoza , Kathrin Liszt , Sabine Widder
IPC: A61K31/365 , A23L27/00 , A23L33/10 , A23F3/40 , A23F5/46 , G01N33/50 , A23L2/52 , A61K47/22 , A61K31/341 , A61K31/353
Abstract: Pharmaceutical preparations are proposed, comprising bitter-masking acting substances for reducing and/or inhibiting gastric acid secretion induced by food constituents.
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公开(公告)号:US10561633B2
公开(公告)日:2020-02-18
申请号:US15329062
申请日:2015-07-26
Applicant: Symrise AG
Inventor: Veronika Somoza , Barbara Rohm , Kathrin Liszt , Marc Pignitter , Christina Hochkogler , Jakob Ley , Sabine Widder , Gerhard Krammer
IPC: A61K31/352 , A23L33/10 , A23C23/00 , A23G3/36 , A23G4/06 , A23L2/52 , C07D311/30
Abstract: The invention relates to compounds of formula (I) or the salts thereof, said compounds of formula (I) being selected from among the group consisting of homoeriodictyol (1), eriodictyol (2), hesperetin (3) and sterubin (4), for use in the treatment of an ailment which can be alleviated or prevented by influencing the serotonin level and the concentration of free fatty acids in the blood.
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公开(公告)号:US20170135982A1
公开(公告)日:2017-05-18
申请号:US15329062
申请日:2015-07-26
Applicant: Symrise AG
Inventor: Veronika Somoza , Barbara Rohn , Kathrin Liszt , Marc Pignitter , Christina Hochkogler , Jakob Ley , Sabine Widder , Gerhard Krammer
IPC: A61K31/352 , A23L33/10 , A23C23/00 , A23G4/06 , A23G3/36 , C07D311/30 , A23L2/52
CPC classification number: A61K31/352 , A23C23/00 , A23G3/36 , A23G4/06 , A23L2/52 , A23L33/10 , A23V2002/00 , C07D311/30
Abstract: The invention relates to compounds of formula (I) or the salts thereof, said compounds of formula (I) being selected from among the group consisting of homoeriodictyol (1), eriodictyol (2), hesperetin (3) and sterubin (4), for use in the treatment of an ailment which can be alleviated or prevented by influencing the serotonin level and the concentration of free fatty acids in the blood.
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公开(公告)号:US20140234412A1
公开(公告)日:2014-08-21
申请号:US14179170
申请日:2014-02-12
Applicant: Symrise AG
Inventor: Jakob Ley , Sabine Widder , Veronika Somoza , Barbara Rohm , Matthias Zaunschirm , Gerhard Krammer
CPC classification number: A23K20/105 , A23L33/10 , A23L33/30 , A61K31/16 , A61K31/164
Abstract: Suggested are new compositions for oral ingestion, comprising at least one active agent from the group of alkamides. The compositions which are orally ingested reduce the uptake of free fatty acids in the adipocytes and at the same time stimulate the release of serotonin and dopamine, which leads to a reduction of appetite, a feeling of satiety and a positive mood. In doing so, the new compositions are thus perfectly suitable to counteract any undesired gain of weight.
Abstract translation: 建议的是用于口服摄取的新组合物,其包含至少一种来自该组烷酰胺的活性剂。 口服摄入的组合物降低脂肪细胞中游离脂肪酸的摄取量,同时刺激5-羟色胺和多巴胺的释放,这导致食欲降低,饱腹感和积极情绪。 因此,新组合物非常适合抵消任何不希望的重量增加。
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公开(公告)号:US10226445B2
公开(公告)日:2019-03-12
申请号:US14761474
申请日:2014-01-15
Applicant: Symrise AG
Inventor: Elke Köck , Jakob Ley , Veronika Somoza , Kathrin Liszt , Sabine Widder
IPC: A61K31/365 , A23L33/10 , A23F3/40 , A23F5/46 , G01N33/50 , A23L2/52 , A61K47/22 , A61K31/341 , A61K31/353 , A23L27/00 , A61K9/00 , A61K9/68 , A61K9/19 , A61K9/48
Abstract: Pharmaceutical preparations are proposed, comprising bitter-masking acting substances for reducing and/or inhibiting gastric acid secretion induced by food constituents.
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公开(公告)号:US20160081977A1
公开(公告)日:2016-03-24
申请号:US14761474
申请日:2014-01-15
Applicant: SYMRISE AG
Inventor: Elke Köck , Jakob Ley , Veronika Somoza , Kathrin Liszt , Sabine Widder
IPC: A61K31/365 , A61K47/22 , A61K31/353 , A61K31/341 , A23L1/22 , A23L1/30
CPC classification number: A61K31/365 , A23F3/405 , A23F5/465 , A23L2/52 , A23L27/86 , A23L33/10 , A23V2002/00 , A61K9/0056 , A61K9/0058 , A61K9/0095 , A61K9/19 , A61K9/4875 , A61K31/341 , A61K31/353 , A61K47/22 , G01N33/5044
Abstract: Pharmaceutical preparations are proposed, comprising bitter-masking acting substances for reducing and/or inhibiting gastric acid secretion induced by food constituents.
Abstract translation: 提出了药物制剂,其包含用于减少和/或抑制由食物成分引起的胃酸分泌的苦味作用物质。
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