公开(公告)号：US20210361820A1

公开(公告)日：2021-11-25

申请号：US16965721

申请日：2018-12-20

申请人： SYSTAGENIX WOUND MANAGEMENT, LIMITED ,  KCI USA, INC.

发明人： Katherine A. BOURDILLON ,  Craig DELURY ,  Sophie REGAN ,  James Sebastian MELLOR ,  Matthew WESTMORELAND

IPC分类号： A61L15/32 ,  A61L15/28 ,  A61L15/46 ,  A61L15/48 ,  C08L89/06 ,  C08L1/02 ,  A61L15/42

摘要： An antimicrobial composition may comprise a surfactant. The antimicrobial composition may include about 30 μg/ml to about 1,000 μg/ml of the surfactant, by volume of the antimicrobial composition. The surfactant may comprise a docusate salt such as docusate sodium. The antimicrobial composition may comprise an antimicrobial agent. The antimicrobial composition may include from about 0.01% to about 10% of the antimicrobial agent, by weight of the antimicrobial composition. The antimicrobial agent may comprise polyhexanide (PHMB). In some embodiments, the antimicrobial composition may comprise a matrix-forming material. The antimicrobial composition may include at least 90% of the matrix-forming material, by weight of the antimicrobial composition. The matrix-forming material may comprise collagen, oxidized regenerated cellulose, alginate, carboxymethylcellulose, or combinations thereof.

公开(公告)号：US20180303912A1

公开(公告)日：2018-10-25

申请号：US15768528

申请日：2016-10-14

申请人： SYSTAGENIX WOUND MANAGEMENT, LIMITED

发明人： Katie BOURDILLON ,  Matthew WESTMORELAND ,  Sophie REGAN

IPC分类号： A61K38/44 ,  A61P31/04 ,  A61K9/00 ,  A61K31/7004

CPC分类号： A61K38/443 ,  A61K9/0014 ,  A61K9/7092 ,  A61K31/7004 ,  A61K38/44 ,  A61P31/04 ,  C12Y101/03004

摘要： A composition comprising an oxidoreductase enzyme and a substrate for the enzyme for use in treating or preventing biofilm formation by a population of pathogenic bacteria. The composition can be incorporated into a wound dressing for use in promoting wound healing.

公开(公告)号：US20220142820A1

公开(公告)日：2022-05-12

申请号：US17433424

申请日：2019-02-27

申请人： Systagenix Wound Management, Limited

发明人： Craig DELURY ,  Sophie REGAN ,  Katie BOURDILLON

IPC分类号： A61F13/00 ,  A61L15/64 ,  A61L15/22 ,  A61L15/14

摘要： A dressing that includes an absorbent, antimicrobial layer and a bioresorbable layer is disclosed herein. The absorbent, antimicrobial layer may be formed from nonwoven fibers. The bioresorbable layer may include an extracellular polymeric substance-active agent, such as citric acid. At least a portion of the nonwoven fibers may include carboxymethylcellulose fibers and alginate fibers.