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公开(公告)号：US20060216767A1
公开(公告)日：2006-09-28
申请号：US11087008
申请日：2005-03-22
IPC分类号： G01N33/53 , C07K16/18 , C07K14/47 , C07D305/12
CPC分类号： C07D305/14 , C07K16/44 , G01N33/532 , G01N33/94 , G01N2407/02 , Y10S436/815
摘要： Novel conjugates of docetaxel and novel docetaxel immunogens derived from the 7 and 10 positions of docetaxel and monoclonal antibodies generated by these docetaxel linked immunogens are useful in immunoassays for the quantification and monitoring of docetaxel in biological fluids.
摘要翻译： 衍生自多西紫杉醇和多烯紫杉醇连接的免疫原产生的单克隆抗体的7和10位的多西他赛和新西兰多西他赛免疫原的新型缀合物可用于免疫测定，用于定量和监测生物流体中的多西他赛。
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公开(公告)号：US20060216769A1
公开(公告)日：2006-09-28
申请号：US11384848
申请日：2006-03-20
IPC分类号： G01N33/53 , C07K16/18 , C07D305/12
CPC分类号： C07D305/14 , C07K16/44 , G01N33/532 , G01N33/94 , G01N2407/02 , Y10S436/815
摘要： Novel conjugates of docetaxel and novel docetaxel immunogens derived from the 7 and 10 positions of docetaxel and monoclonal antibodies generated by these docetaxel linked immunogens are useful in immunoassays for the quantification and monitoring of docetaxel in biological fluids.
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公开(公告)号：US20060024748A1
公开(公告)日：2006-02-02
申请号：US11072910
申请日：2005-03-04
摘要： Novel conjugates of protected aldehyde active metabolites of cyclophosphamide including reagents and immunogens thereof and monoclonal antibodies generated by these immunogens, said reagents and immunogens useful in immunoassays for the monitoring of the active metabolites of cyclophosphamide in patients being treated with cyclophosphamide.
摘要翻译： 包括试剂及其免疫原的环磷酰胺的保护醛活性代谢物和由这些免疫原产生的单克隆抗体的新型缀合物，所述试剂和免疫原用于免疫测定，用于监测用环磷酰胺治疗的患者中环磷酰胺的活性代谢物。
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公开(公告)号：US20070092922A1
公开(公告)日：2007-04-26
申请号：US11606721
申请日：2006-11-30
CPC分类号： G01N33/94 , G01N33/5308 , G01N2407/02 , Y10S436/815
摘要： Novel conjugates of taxol and novel taxol immunogens derived from the 9 and 7 positions of taxol and monoclonal antibodies generated by these taxol linked immunogens are useful in immunoassays for the quantification and monitoring of taxol in biological fluids.
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公开(公告)号：US20070077608A1
公开(公告)日：2007-04-05
申请号：US11544977
申请日：2006-10-06
申请人： Salvatore Salamone , Jodi Courtney , Shu He
发明人： Salvatore Salamone , Jodi Courtney , Shu He
CPC分类号： G01N33/5308 , C07C311/06 , C07D207/46 , C07K16/44 , G01N33/94 , Y10S435/81 , Y10S435/961 , Y10S436/815 , Y10S530/807 , Y10T436/13
摘要： Novel conjugates of busulfan and novel busulfan immunogens derived from α-substituted derivatives of busulfan and antibodies generated by these busulfan linked immunogens are useful in immunoassays for the quantification and monitoring of busulfan in biological fluids.
摘要翻译： 来自白消安的α-取代衍生物和由这些白消安相关免疫原产生的抗体的白消安和新型白消安免疫原的新型缀合物可用于定量和监测生物流体中白消安的免疫测定。
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公开(公告)号：US20060223134A1
公开(公告)日：2006-10-05
申请号：US11389934
申请日：2006-03-27
申请人： Salvatore Salamone , Jodi Courtney , Shu He
发明人： Salvatore Salamone , Jodi Courtney , Shu He
CPC分类号： G01N33/9446 , A61K47/646 , C07K16/44 , G01N33/94 , Y10S530/807
摘要： Novel conjugates of doxorubicin and novel doxorubicin immunogens derived from the 13 and 14 positions of doxorubicin and antibodies generated by these doxorubicin linked immunogens all of which are useful in immunoassays for the quantification and monitoring of doxorubicin in biological fluids.
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公开(公告)号：US20060057656A1
公开(公告)日：2006-03-16
申请号：US11225613
申请日：2005-09-13
申请人： Salvatore Salamone , Jodi Courtney , Shu He
发明人： Salvatore Salamone , Jodi Courtney , Shu He
IPC分类号： G01N33/537 , G01N33/53 , G01N33/543
CPC分类号： G01N33/5308 , C07C311/06 , C07D207/46 , C07K16/44 , G01N33/94 , Y10S435/81 , Y10S435/961 , Y10S436/815 , Y10S530/807 , Y10T436/13
摘要： Novel conjugates of busulfan and novel busulfan immunogens derived from α-substituted derivatives of busulfan and antibodies generated by these busulfan linked immunogens are useful in immunoassays for the quantification and monitoring of busulfan in biological fluids.
摘要翻译： 来自白消安的α-取代衍生物和由这些白消安结合的免疫原产生的抗体的白消安和新的白消安免疫原的新型缀合物可用于免疫测定用于定量和监测生物流体中的百日咳。
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公开(公告)号：US20060099665A1
公开(公告)日：2006-05-11
申请号：US11301101
申请日：2005-12-12
IPC分类号： G01N33/537
CPC分类号： G01N33/94 , G01N33/5308 , G01N2407/02 , Y10S436/815
摘要： Novel conjugates of taxol and novel taxol immunogens derived from the 9 and 7 positions of taxol and monoclonal antibodies generated by these taxol linked immunogens are useful in immunoassays for the quantification and monitoring of taxol in biological fluids.
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公开(公告)号：US20060024769A1
公开(公告)日：2006-02-02
申请号：US11191497
申请日：2005-07-28
IPC分类号： G01N33/53
CPC分类号： G01N33/94 , G01N33/5308 , G01N2407/02 , Y10S436/815
摘要： Novel conjugates of taxol and novel taxol immunogens derived from the 9 and 7 positions of taxol and monoclonal antibodies generated by these taxol linked immunogens are useful in immunoassays for the quantification and monitoring of taxol in biological fluids.
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公开(公告)号：US20070154972A1
公开(公告)日：2007-07-05
申请号：US11709109
申请日：2007-02-20
IPC分类号： G01N33/53 , C07K16/18 , C07K14/47 , C07D239/54
CPC分类号： G01N33/94 , Y10S435/81 , Y10S435/961 , Y10S435/975 , Y10S436/815 , Y10S530/811 , Y10T436/13
摘要： Novel conjugates of 5-fluoro-uracil and novel 5-fluoro-uracil immunogens and monoclonal antibodies generated by these immunogens which are useful in immunoassays for the quantification and monitoring of 5-fluoro-uracil in biological fluids.
摘要翻译： 5-氟尿嘧啶和新型5-氟尿嘧啶免疫原的新结合物和由这些免疫原产生的单克隆抗体，其可用于免疫测定以定量和监测生物体液中5-氟尿嘧啶。
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