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公开(公告)号:US20110238336A1
公开(公告)日:2011-09-29
申请号:US13121092
申请日:2009-09-25
申请人: Francesco Lanza Di Scalea , Stefano Coccia , Ivan Bartoli , Salvatore Salamone , Piervincenzo Rizzo
发明人: Francesco Lanza Di Scalea , Stefano Coccia , Ivan Bartoli , Salvatore Salamone , Piervincenzo Rizzo
CPC分类号: G01N29/221 , G01N29/043 , G01N29/4418 , G01N2291/2623
摘要: Disclosed are systems, methods and articles, including an inspection system that includes at least one generator to apply energy to an object at an application point to cause waves to travel, at least partly, through the object. The system further includes at least one detector configured to detect at least a portion of the waves traveling through the object, and a statistical analyzer to perform a statistical analysis based on an output produced by the at least one detector in response to the detected portion of the waves, the statistical analysis being used to determine whether at least one defect is present in the object.
摘要翻译: 所公开的系统,方法和物品,包括检查系统,其包括至少一个发生器,以在应用点向物体施加能量,以使波浪至少部分地通过物体行进。 所述系统还包括至少一个检测器,其被配置为检测穿过物体的波的至少一部分;以及统计分析器,用于基于所述至少一个检测器响应于检测到的部分的输出而执行统计分析 波形,统计分析用于确定对象中是否存在至少一个缺陷。
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公开(公告)号:US20060216767A1
公开(公告)日:2006-09-28
申请号:US11087008
申请日:2005-03-22
IPC分类号: G01N33/53 , C07K16/18 , C07K14/47 , C07D305/12
CPC分类号: C07D305/14 , C07K16/44 , G01N33/532 , G01N33/94 , G01N2407/02 , Y10S436/815
摘要: Novel conjugates of docetaxel and novel docetaxel immunogens derived from the 7 and 10 positions of docetaxel and monoclonal antibodies generated by these docetaxel linked immunogens are useful in immunoassays for the quantification and monitoring of docetaxel in biological fluids.
摘要翻译: 衍生自多西紫杉醇和多烯紫杉醇连接的免疫原产生的单克隆抗体的7和10位的多西他赛和新西兰多西他赛免疫原的新型缀合物可用于免疫测定,用于定量和监测生物流体中的多西他赛。
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公开(公告)号:US20060024748A1
公开(公告)日:2006-02-02
申请号:US11072910
申请日:2005-03-04
摘要: Novel conjugates of protected aldehyde active metabolites of cyclophosphamide including reagents and immunogens thereof and monoclonal antibodies generated by these immunogens, said reagents and immunogens useful in immunoassays for the monitoring of the active metabolites of cyclophosphamide in patients being treated with cyclophosphamide.
摘要翻译: 包括试剂及其免疫原的环磷酰胺的保护醛活性代谢物和由这些免疫原产生的单克隆抗体的新型缀合物,所述试剂和免疫原用于免疫测定,用于监测用环磷酰胺治疗的患者中环磷酰胺的活性代谢物。
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公开(公告)号:US20060216769A1
公开(公告)日:2006-09-28
申请号:US11384848
申请日:2006-03-20
IPC分类号: G01N33/53 , C07K16/18 , C07D305/12
CPC分类号: C07D305/14 , C07K16/44 , G01N33/532 , G01N33/94 , G01N2407/02 , Y10S436/815
摘要: Novel conjugates of docetaxel and novel docetaxel immunogens derived from the 7 and 10 positions of docetaxel and monoclonal antibodies generated by these docetaxel linked immunogens are useful in immunoassays for the quantification and monitoring of docetaxel in biological fluids.
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公开(公告)号:US20060099665A1
公开(公告)日:2006-05-11
申请号:US11301101
申请日:2005-12-12
IPC分类号: G01N33/537
CPC分类号: G01N33/94 , G01N33/5308 , G01N2407/02 , Y10S436/815
摘要: Novel conjugates of taxol and novel taxol immunogens derived from the 9 and 7 positions of taxol and monoclonal antibodies generated by these taxol linked immunogens are useful in immunoassays for the quantification and monitoring of taxol in biological fluids.
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公开(公告)号:US20060024769A1
公开(公告)日:2006-02-02
申请号:US11191497
申请日:2005-07-28
IPC分类号: G01N33/53
CPC分类号: G01N33/94 , G01N33/5308 , G01N2407/02 , Y10S436/815
摘要: Novel conjugates of taxol and novel taxol immunogens derived from the 9 and 7 positions of taxol and monoclonal antibodies generated by these taxol linked immunogens are useful in immunoassays for the quantification and monitoring of taxol in biological fluids.
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公开(公告)号:US20050009076A1
公开(公告)日:2005-01-13
申请号:US10900447
申请日:2004-07-27
申请人: Mitali Ghoshal , Gerald Sigler , Raymond Hui , Ronald Hawley , Eva Hoess , Erasmus Huber , John Patterson , Salvatore Salamone , Allan Dorn
发明人: Mitali Ghoshal , Gerald Sigler , Raymond Hui , Ronald Hawley , Eva Hoess , Erasmus Huber , John Patterson , Salvatore Salamone , Allan Dorn
IPC分类号: G01N33/531 , C07D307/88 , C07D405/12 , C07D473/08 , C07J19/00 , C07J41/00 , C07J43/00 , G01N33/53 , G01N33/535 , G01N33/573 , G01N33/58 , G01N33/78 , G01N33/94 , C12Q1/68 , C07H15/24 , C07H21/04 , C07J17/00
CPC分类号: C07D405/12 , C07D307/88 , C07D473/08 , C07H15/20 , C07H15/22 , C07H15/24 , C07J17/00 , C07J19/005 , C07J41/0005 , C07J41/0055 , C07J43/003 , G01N33/53 , G01N33/535 , G01N33/5735 , G01N33/581 , G01N33/78 , G01N33/9453 , G01N2333/904
摘要: The present invention provides a method for the measurement of an analyte in biological samples whereby an uncompetitive inhibitor is coupled to a ligand and utilized in a homogeneous assay. The analyte can be a drug or drug derivative, hormone, polypeptide, or oligonucleotide. The present invention also provides novel compounds, assay reagents and packaged kits useful for performing such measurements.
摘要翻译: 本发明提供了一种用于测量生物样品中分析物的方法,由此使非竞争性抑制剂与配体偶联并用于均匀测定。 分析物可以是药物或药物衍生物,激素,多肽或寡核苷酸。 本发明还提供了可用于进行这种测量的新型化合物,测定试剂和包装的试剂盒。
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公开(公告)号:US08440442B2
公开(公告)日:2013-05-14
申请号:US12839336
申请日:2010-07-19
CPC分类号: G01N33/94 , A61B5/15003 , A61B5/150236 , A61B5/150244 , A61B5/150351 , A61B5/150389 , A61B5/150503 , A61B5/150717 , A61B5/150755 , A61B5/153 , A61B5/154 , A61K31/505 , A61K31/513 , C12Q1/32
摘要: The present invention provides methods, compositions, devices and kits for assaying 5-FU.
摘要翻译: 本发明提供了用于测定5-FU的方法,组合物,装置和试剂盒。
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公开(公告)号:US20070154972A1
公开(公告)日:2007-07-05
申请号:US11709109
申请日:2007-02-20
IPC分类号: G01N33/53 , C07K16/18 , C07K14/47 , C07D239/54
CPC分类号: G01N33/94 , Y10S435/81 , Y10S435/961 , Y10S435/975 , Y10S436/815 , Y10S530/811 , Y10T436/13
摘要: Novel conjugates of 5-fluoro-uracil and novel 5-fluoro-uracil immunogens and monoclonal antibodies generated by these immunogens which are useful in immunoassays for the quantification and monitoring of 5-fluoro-uracil in biological fluids.
摘要翻译: 5-氟尿嘧啶和新型5-氟尿嘧啶免疫原的新结合物和由这些免疫原产生的单克隆抗体,其可用于免疫测定以定量和监测生物体液中5-氟尿嘧啶。
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公开(公告)号:US20060177884A1
公开(公告)日:2006-08-10
申请号:US11345706
申请日:2006-02-02
IPC分类号: G01N33/537 , G01N33/53
CPC分类号: G01N33/94 , Y10S435/81 , Y10S435/961 , Y10S435/975 , Y10S436/815 , Y10S530/811 , Y10T436/13
摘要: Novel conjugates of 5-fluoro-uracil and novel 5-fluoro-uracil immunogens and monoclonal antibodies generated by these immunogens which are useful in immunoassays for the quantification and monitoring of 5-fluoro-uracil in biological fluids.
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