公开(公告)号：US20140256045A1

公开(公告)日：2014-09-11

申请号：US14198124

申请日：2014-03-05

Applicant: Samsung Electronics Co., Ltd.

Inventor： Soon-chun CHUNG ,  Hyun-min Koo ,  Ji-eun Kim ,  Jae-chan Park ,  Joon-song Park ,  Ju-young Lee

IPC: C12N15/85 ,  C12N15/80 ,  C12N15/81

CPC classification number: C12N15/80 ,  C12N15/81 ,  C12N15/815

Abstract: Provided is a method of simultaneous co-integration of multiple nucleic acid sequences into a microbial organism comprising culturing a microbial organism to be transformed until a growth phase is reached in which a random integration is facilitated; and transforming the microbial organism by mixing the cultured microbial organism with a sample to be co-integrated into the microbial organism with, wherein the sample comprises more than one nucleic acid sequence, and the products generated from the method.

Abstract translation: 提供了将多个核酸序列同时整合到微生物生物体中的方法，包括培养要转化的微生物，直到达到促进随机整合的生长期; 以及通过将培养的微生物与待共同整合到微生物中的样品混合培养微生物生物体，其中样品包含多于一种的核酸序列，以及由该方法生成的产物。

公开(公告)号：US09404116B2

公开(公告)日：2016-08-02

申请号：US14198124

申请日：2014-03-05

Applicant: Samsung Electronics Co., Ltd.

Inventor： Soon-chun Chung ,  Hyun-min Koo ,  Ji-eun Kim ,  Jae-chan Park ,  Joon-song Park ,  Ju-young Lee

IPC: A01N63/00 ,  C12N15/80 ,  C12N15/81

CPC classification number: C12N15/80 ,  C12N15/81 ,  C12N15/815

Abstract: Provided is a method of simultaneous co-integration of multiple nucleic acid sequences into a microbial organism comprising culturing a microbial organism to be transformed until a growth phase is reached in which a random integration is facilitated; and transforming the microbial organism by mixing the cultured microbial organism with a sample to be co-integrated into the microbial organism with, wherein the sample comprises more than one nucleic acid sequence, and the products generated from the method.

Abstract translation: 提供了将多个核酸序列同时整合到微生物生物体中的方法，包括培养要转化的微生物，直到达到促进随机整合的生长期; 以及通过将培养的微生物与待共同整合到微生物中的样品混合培养微生物生物体，其中样品包含多于一种的核酸序列，以及由该方法生成的产物。

公开(公告)号：US09068188B2

公开(公告)日：2015-06-30

申请号：US14088111

申请日：2013-11-22

Applicant: Samsung Electronics Co., Ltd.

Inventor： Ji-ae Yun ,  Joon-song Park ,  Woo-yong Lee ,  Jae-chan Park ,  Jin-hwan Park

IPC: C12N15/77 ,  C07K14/34

CPC classification number: C12N15/77 ,  C07K14/34

Abstract: An isolated nucleic acid comprising a promoter region having a nucleotide sequence of SEQ ID NO: 1, which can maintain high expression under aerobic and anaerobic conditions, and related compositions and methods.

Abstract translation: 一种分离的核酸，其包含具有SEQ ID NO：1的核苷酸序列的启动子区，其可以在需氧和厌氧条件下保持高表达，以及相关的组合物和方法。