公开(公告)号：US09157086B2

公开(公告)日：2015-10-13

申请号：US14163743

申请日：2014-01-24

Applicant: Samsung Electronics Co., Ltd

Inventor： Woo-yong Lee ,  Young-min Lee ,  Jae-chan Park ,  Jin-hwan Park ,  Yeo-ju Song

IPC: C12N15/77 ,  C12N15/70

CPC classification number: C12N15/77 ,  C12N15/70

Abstract: A vector that allows for easy accomplishment of a variety of cloning, and use of the vector for measurement of the transcription-inducing activity of a promoter or production of a desired gene product in Corynebacterium.

Abstract translation: 允许容易地完成各种克隆的载体，以及使用载体来测量启动子的转录诱导活性或在棒状杆菌中产生所需基因产物。

公开(公告)号：US09068188B2

公开(公告)日：2015-06-30

申请号：US14088111

申请日：2013-11-22

Applicant: Samsung Electronics Co., Ltd.

Inventor： Ji-ae Yun ,  Joon-song Park ,  Woo-yong Lee ,  Jae-chan Park ,  Jin-hwan Park

IPC: C12N15/77 ,  C07K14/34

CPC classification number: C12N15/77 ,  C07K14/34

Abstract: An isolated nucleic acid comprising a promoter region having a nucleotide sequence of SEQ ID NO: 1, which can maintain high expression under aerobic and anaerobic conditions, and related compositions and methods.

Abstract translation: 一种分离的核酸，其包含具有SEQ ID NO：1的核苷酸序列的启动子区，其可以在需氧和厌氧条件下保持高表达，以及相关的组合物和方法。

公开(公告)号：US09416379B2

公开(公告)日：2016-08-16

申请号：US13952410

申请日：2013-07-26

Applicant: Samsung Electronics Co., Ltd.

Inventor： Kyu-sang Lee ,  Young-min Lee ,  Woo-yong Lee ,  Hyun-min Koo ,  Jin-woo Kim ,  Young-kyoung Park ,  Jin-hwan Park ,  Hwa-young Cho ,  Jae-chan Park

IPC: C12N1/20 ,  C12P7/18 ,  C12N15/77 ,  C12N9/04 ,  C12N15/52

CPC classification number: C12P7/18 ,  C12N9/0006 ,  C12N15/52 ,  C12N15/77 ,  C12Y101/01037 ,  C12Y101/05004 ,  Y02P20/52

Abstract: A recombinantly modified Corynebacterium glutamicum microorganism with an improved 1,4-butanediol (1,4-BDO) productivity relative to an unmodified Corynebacterium glutamicum microorganism, wherein activity of an enzyme catalyzing a conversion reaction between malate and oxaloacetate is inactivated or reduced relative to an unmodified Corynebacterium glutamicum microorganism, as well as a method of making and using same.

Abstract translation: 相对于未修饰的谷氨酸棒杆菌微生物，具有改进的1,4-丁二醇（1,4-BDO）生产力的重组修饰的谷氨酸棒杆菌微生物，其中催化苹果酸和草酰乙酸之间的转化反应的酶的活性相对于 未经修饰的谷氨酸棒杆菌微生物，以及其制备和使用方法。

公开(公告)号：US09121042B2

公开(公告)日：2015-09-01

申请号：US13954696

申请日：2013-07-30

Applicant: Samsung Electronics Co. Ltd. ,  Ajou University Industry-Academic Cooperation Foundation

Inventor： Jin-hwan Park ,  Pyung-cheon Lee ,  Jae-chan Park ,  Young-min Lee ,  Woo-yong Lee

IPC: C12P7/24 ,  C12N9/42 ,  C12N1/20 ,  C12N15/00 ,  C07H21/04 ,  C12P7/18 ,  C12N9/04 ,  C12N9/02

CPC classification number: C12P7/18 ,  C12N9/0006 ,  C12N9/0008 ,  C12P7/24

Abstract: Recombinant butyraldehyde dehydrogenases (Blds) with improved production of 1,4-BDO, as well as recombinant microorganisms comprising polynucleotides encoding the recombinant Blds, and methods of producing 1,4-BDO by using the recombinant microorganisms.

Abstract translation: 具有改进的1,4-BDO生产的重组丁醛脱氢酶（Blds），以及包含编码重组Bld的多核苷酸的重组微生物，以及通过使用重组微生物产生1,4-BDO的方法。