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Patent Agency Ranking
公开(公告)号：US10472682B2
公开(公告)日：2019-11-12
申请号：US14869563
申请日：2015-09-29
Applicant: Samsung Electronics Co., Ltd.
Inventor： Seon Hui Shim , Soo Yeon Jung , Kyung Ah Kim
IPC: C12Q1/6886 , C07K16/30 , C07K16/28 , A61K39/00
Abstract: A method for predicting and/or monitoring the efficacy of a c-Met inhibitor using a biomarker; a method for selecting a subject suitable for the application of a c-Met inhibitor using a biomarker; and a method for preventing and/or treating cancer comprising administering a c-Met inhibitor to the selected subject.
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2.发明申请PREDICTION OF EFFECT OF A C-MET INHIBITOR USING MUTATION OF KRAS OR BRAF 审中-公开使用KRAS或BRAF的突变预测C-MET抑制剂的作用公开(公告)号：US20160090635A1
公开(公告)日：2016-03-31
申请号：US14869563
申请日：2015-09-29
Applicant: Samsung Electronics Co., Ltd.
Inventor： Seon Hui Shim , Soo Yeon Jung , Kyung Ah Kim
Abstract: A method for predicting and/or monitoring the efficacy of a c-Met inhibitor using a biomarker; a method for selecting a subject suitable for the application of a c-Met inhibitor using a biomarker; and a method for preventing and/or treating cancer comprising administering a c-Met inhibitor to the selected subject.
Abstract translation: 使用生物标志物预测和/或监测c-Met抑制剂的功效的方法; 用于使用生物标志物选择适合于应用c-Met抑制剂的受试者的方法; 以及用于预防和/或治疗癌症的方法，包括向所选择的受试者施用c-Met抑制剂。
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3.发明授权公开(公告)号：US10064939B2
公开(公告)日：2018-09-04
申请号：US14949041
申请日：2015-11-23
Inventor： Seon Hui Shim , Ji Min Lee , Soo Yeon Jung , Woo Sun Kwon , Kyung Ah Kim , Jeong Min Kim , Sun Young Rha , Won Suk Lee
IPC: A61K39/395 , A61K31/00 , C07K16/28 , A61K31/4985 , G01N33/574 , G01N33/74 , A61K39/00
Abstract: A method of preventing and/or treating a cancer, the method including co-administering a dual inhibitor of c-Met (hereinafter, ‘c-Met inhibitor’) and an IGF-1R inhibitor to a subject in need thereof and a use of IGF-1R as a marker for resistance to a c-Met inhibitor.
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公开(公告)号：US10393748B2
公开(公告)日：2019-08-27
申请号：US14591787
申请日：2015-01-07
Applicant: Samsung Electronics Co., Ltd.
Inventor： Soo Yeon Jung , Seon Hui Shim , Yun Jeong Song , Hyeon-seok Yoo
IPC: G01N33/50 , G01N33/574 , C07K16/40 , C12Q1/6886 , A61K39/00
Abstract: A biomarker for predicting and/or monitoring the efficacy of a c-Met inhibitor; a composition for predicting and/or monitoring the efficacy of a c-Met inhibitor, comprising a material detecting the biomarker; a composition for selecting a subject suitable for the application of a c-Met inhibitor, comprising a material detecting the biomarker; a method for predicting and/or monitoring the efficacy of a c-Met inhibitor using the biomarker; a method for selecting a subject suitable for the application of a c-Met inhibitor using the biomarker; and a method for preventing and/or treating cancer comprising administering a c-Met inhibitor to the selected subject.
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5.发明申请公开(公告)号：US20160144027A1
公开(公告)日：2016-05-26
申请号：US14949041
申请日：2015-11-23
Inventor： Seon Hui Shim , Ji Min Lee , Soo Yeon Jung , Woo Sun Kwon , Kyung Ah Kim , Jeong Min Kim , Sun Young Rha , Won Suk Lee
IPC: A61K39/395 , G01N33/574 , A61K31/4985
CPC classification number: A61K39/39558 , A61K31/00 , A61K31/4985 , A61K2039/505 , C07K16/2863 , C07K2317/24 , C07K2317/52 , C07K2317/622 , C07K2317/92 , C07K2319/00 , G01N33/57492 , G01N33/74 , G01N2333/65 , G01N2800/52 , A61K2300/00
Abstract: A method of preventing and/or treating a cancer, the method including co-administering a dual inhibitor of c-Met (hereinafter, ‘c-Met inhibitor’) and an IGF-1R inhibitor to a subject in need thereof and a use of IGF-1R as a marker for resistance to a c-Met inhibitor.
Abstract translation: 一种预防和/或治疗癌症的方法，所述方法包括将c-Met（以下称为“c-Met抑制剂”）和IGF-1R抑制剂的双重抑制剂共同给予有需要的受试者，以及使用 IGF-1R作为c-Met抑制剂抗性的标志物。
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