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公开(公告)号：US20220118191A1
公开(公告)日：2022-04-21
申请号：US17563465
申请日：2021-12-28
发明人： Christian Rehbein , Samuel Steel , Anthony Paul Morris , Matthew Meredith Jones , Robert Veasey , Richard James Vincent Avery , William Marsh
摘要： A sensor device removably attachable to a drug delivery device includes a sensing arrangement arranged within the sensor device and circuitry configured to process signals provided by the sensing arrangement. The sensing arrangement is configured such that, when the sensor device is attached to the drug delivery device, the sensing arrangement is operable to read encoded information present on a rotatable component internal to the drug delivery device and that is able to be sensed through a window or aperture of the drug delivery device, and is operable to sense through the window or aperture at least a part of a drive mechanism of the drug delivery device. The circuitry is configured to determine information relating to a set dose, and to determine information relating to whether the drug delivery device is in a dose setting mode or whether the device is in a dose delivery mode.
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公开(公告)号：US20210393891A1
公开(公告)日：2021-12-23
申请号：US17146948
申请日：2021-01-12
摘要： A method and system for detecting a limit of use of a medical device is disclosed. The method includes starting a timer of a medical device when said medical device is used for the first time, detecting the limit of use of the medical device and indicating the limit of use of the medical device. The limit of use is reached when at least one of a first criterion and a second criterion is met, wherein the first criterion is that the timer reaches or exceeds a time limit and wherein the second criterion is that at least one operation of a drive train of said medical device reaches or exceeds a limit.
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公开(公告)号：US11147739B2
公开(公告)日：2021-10-19
申请号：US16162141
申请日：2018-10-16
摘要： A coded collapsible drug reservoir and a drug delivery system including the coded collapsible drug reservoir. The drug reservoir includes a collapsible housing and a port in communication with the collapsible housing. The drug reservoir further includes a coding feature disposed on the drug reservoir, and the coding feature identifies the drug reservoir.
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公开(公告)号：US10426895B2
公开(公告)日：2019-10-01
申请号：US15517719
申请日：2015-10-09
申请人： Sanofi
发明人： William Marsh , Anthony Paul Morris , Joseph Butler , Matthew Jones , Samuel Steel , Richard James Vincent Avery
摘要： The present disclosure relates to a drive mechanism which is suitable for an injection device, especially a pen type drug delivery device and to such a drug delivery device. The mechanism comprises a spring driven rotatable drive member, a rotatable driven member, a clutch rotationally coupling the driven member and the drive member in a coupled state and allowing relative clockwise and anti-clockwise rotation between the driven member and the drive member in a decoupled state, and a spring biasing the clutch into its coupled state and allowing relative axial movement between the drive member and the driven member into the decoupled state of the clutch against the bias of the spring. The clutch comprises a first ring of crown teeth on the drive member and a second ring of corresponding crown teeth on the driven member with each crown tooth having in the clockwise and the anti-clockwise direction different ramped tooth angles such that the teeth are allowed to override each other in the de-coupled state of the clutch with a different resistance in the clockwise and the anti-clockwise direction.
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公开(公告)号：US10220154B2
公开(公告)日：2019-03-05
申请号：US15321900
申请日：2015-07-01
申请人： Sanofi
发明人： William Marsh , Anthony Paul Morris , Joseph Butler , Matthew Jones , Samuel Steel , Richard James Vincent Avery
摘要： The present disclosure is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing (10), a dose selector (80) operable to set a dose by rotation relative to the housing (10), a number sleeve (60) arranged within the housing (10) such that at least a portion of the number sleeve (60) is visible through a first aperture (11b) in the housing (10), a piston rod (30) coupled to the housing (10) and to a drive sleeve (40) such that rotation of the drive sleeve (40) relative to the housing (10) causes the piston rod (30) to translate relative to the housing (10) and a clutch mechanism arranged between the number sleeve (60) and the drive sleeve (40). The clutch mechanism comprises a first interface (42, 62) for rotationally constraining the drive sleeve (40) and the number sleeve (60) depending on the axial position of the drive sleeve (40) and a second interface (43, 121) for rotationally constraining the drive sleeve (40) and the number sleeve (60) via a clutch element (120) depending on the axial position of the drive sleeve (40) and/or the bias of a clutch spring (130).
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公开(公告)号：US20180078717A1
公开(公告)日：2018-03-22
申请号：US15805928
申请日：2017-11-07
CPC分类号： A61M5/5086 , A61M5/20 , A61M5/24 , A61M2205/273
摘要： A method and system for detecting a limit of use of a medical device is disclosed. The method includes starting a timer of a medical device when said medical device is used for the first time, detecting the limit of use of the medical device and indicating the limit of use of the medical device. The limit of use is reached when at least one of a first criterion and a second criterion is met, wherein the first criterion is that the timer reaches or exceeds a time limit and wherein the second criterion is that at least one operation of a drive train of said medical device reaches or exceeds a limit.
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公开(公告)号：US20180050155A1
公开(公告)日：2018-02-22
申请号：US15557338
申请日：2016-03-11
申请人： SANOFI
发明人： Richard James Vincent Avery , Matthew Meredith Jones , William Marsh , Anthony Paul Morris , David Aubrey Plumptre , Samuel Keir Steel , Robert Frederick Veasey
CPC分类号： A61M5/20 , A61M5/31541 , A61M5/31553 , A61M5/3157 , A61M5/31583 , A61M5/31593 , A61M2005/2407 , A61M2005/3126 , A61M2205/3306 , A61M2205/50 , A61M2205/581 , A61M2205/582 , A61M2205/583
摘要： The present disclosure is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing and at least two separate component parts, wherein for example at least one of these component parts performs a movement relative to the housing during dose setting and for example at least one of these component parts performs a movement relative to the housing during dose dispensing, and wherein the relative movement of the at least two separate component parts with respect to each other during dose setting differs from the relative movement of the at least two separate component parts with respect to each other during dose dispensing. The device further comprises a monitoring device, wherein at least one component part of the device is diaphanous to allow optical detection of the movements of the at least two separate component parts relative to the housing, relative to the monitoring device and/or relative to each other during dose setting and/or during dose dispensing by the monitoring device.
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8.发明申请公开(公告)号：US20170296754A1
公开(公告)日：2017-10-19
申请号：US15517817
申请日：2015-10-09
申请人： Sanofi
CPC分类号： A61M5/31551 , A61M5/20 , A61M5/2033 , A61M5/31535 , A61M5/31541 , A61M5/31553 , A61M5/3157 , A61M5/31583 , A61M5/31593 , A61M2005/202 , A61M2005/3126 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/584
摘要： The present disclosure is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing, a dose selector operable to set a dose by rotation relative to the housing, a number sleeve arranged within the housing, a drive sleeve which is rotationally constrained to the housing during dose setting and dose correcting and which is rotatable relative to the housing during dose dispensing, a piston rod coupled to the housing and to the drive sleeve a drive spring arranged between the housing and the number sleeve, and a ratchet operatively arranged between the drive sleeve and the number sleeve. According to the disclosure the ratchet comprises at least one clicker arm of one of the number sleeve and the drive sleeve and ratchet teeth of the other of the number sleeve and the drive sleeve.
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9.发明申请公开(公告)号：US20170259006A1
公开(公告)日：2017-09-14
申请号：US15528623
申请日：2015-11-24
申请人： Sanofi
发明人： Richard James Vincent Avery , Matthew Meredith Jones , William Geoffrey Arthur Marsh , Anthony Paul Morris , David Aubrey Plumptre , Samuel Keir Steel , James Alexander Senior , Robert Frederick Veasey
CPC分类号： A61M5/31538 , A61M5/20 , A61M5/24 , A61M5/31541 , A61M5/31553 , A61M5/31561 , A61M5/3157 , A61M5/31583 , A61M5/31585 , A61M5/329 , A61M2005/3126 , A61M2005/3154 , A61M2205/581 , A61M2205/582 , A61M2205/583
摘要： The present disclosure concerns a mechanism for setting a dose of a medicament for a variable dose drug delivery device, comprising: a housing, a sleeve component configured to rotate relative to the housing during a dose setting operation, and a stop member which is configured to limit a total amount of possible rotation of the sleeve component to a maximum and, thereby, to limit a maximum settable dose, wherein the stop member is configured to allow varying the maximum which determines the total amount of possible rotation of the sleeve component.
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公开(公告)号：US11185633B2
公开(公告)日：2021-11-30
申请号：US15322030
申请日：2015-07-01
申请人： Sanofi
发明人： William Marsh , Anthony Paul Morris , Joseph Butler , Matthew Jones , Samuel Steel , Richard James Vincent Avery
摘要： The present disclosure is directed to a spring arrangement for use in a drug delivery device and a drug delivery device including such a spring arrangement. The spring arrangement includes a clutch spring which is located axially interposed between a stationary housing component and an axially movable sleeve. The sleeve includes clutch features adapted to engage corresponding clutch features of a clutch element. The clutch spring biases the clutch features and the corresponding clutch features into engagement. The sleeve is coupled to a button such that upon actuation of the button the sleeve is translated against the bias of the clutch spring from a proximal position in which the sleeve is rotationally locked to the housing component into a distal position in which the sleeve is rotationally un-locked from the housing component. Upon release of the button the clutch spring translates the sleeve and the button into the proximal position.
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