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    Transdermal preparation
    1.
    发明授权
    Transdermal preparation 有权
    透皮制剂

    公开(公告)号：US08702664B2

    公开(公告)日：2014-04-22

    申请号：US13201999

    申请日：2010-02-09

    申请人： Satoshi Amano ,  Tomohiro Shinoda ,  Natsumi Kase ,  Keita Mori

    发明人： Satoshi Amano ,  Tomohiro Shinoda ,  Natsumi Kase ,  Keita Mori

    IPC分类号： A61M35/00

    CPC分类号： A61K9/7084 ,  A61K31/138

    摘要： By providing a non-liquid drug reservoir layer 2 having first and second principal surfaces and containing a drug and a polymer that is to be a base, a drug permeation layer 4 disposed at the first principal surface side of the drug reservoir layer 2 and being lower in permeability of the drug than the drug reservoir layer 2, and a first backing 3 with a bending resistance of 10 to 80 mm that is formed so as to cover a side surface of the drug reservoir layer, skin irritation can be reduced.

    摘要翻译： 通过设置具有第一主表面和第二主表面并且含有药物和要成为基底的聚合物的非液体药物储存层2，设置在药物储存层2的第一主表面侧的药物渗透层4， 药物的透过率低于药物贮存层2，并且形成为覆盖药物储存层的侧面的抗弯曲性为10〜80mm的第一背衬3，因此可以降低皮肤刺激性。

    TRANSDERMAL PREPARATION
    2.
    发明申请
    TRANSDERMAL PREPARATION 有权
    变态准备

    公开(公告)号：US20120029446A1

    公开(公告)日：2012-02-02

    申请号：US13201999

    申请日：2010-02-09

    申请人： Satoshi Amano ,  Tomohiro Shinoda ,  Natsumi Kase ,  Keita Mori

    发明人： Satoshi Amano ,  Tomohiro Shinoda ,  Natsumi Kase ,  Keita Mori

    IPC分类号： A61M35/00

    CPC分类号： A61K9/7084 ,  A61K31/138

    摘要： By providing a non-liquid drug reservoir layer 2 having first and second principal surfaces and containing a drug and a polymer that is to be a base, a drug permeation layer 4 disposed at the first principal surface side of the drug reservoir layer 2 and being lower in permeability of the drug than the drug reservoir layer 2, and a first backing 3 with a bending resistance of 10 to 80 mm that is formed so as to cover a side surface of the drug reservoir layer, skin irritation can be reduced.

    摘要翻译： 通过设置具有第一主表面和第二主表面并且含有药物和要成为基底的聚合物的非液体药物储存层2，设置在药物储存层2的第一主表面侧的药物渗透层4， 药物的透过率低于药物贮存层2，并且形成为覆盖药物储存层的侧面的抗弯曲性为10〜80mm的第一背衬3，因此可以降低皮肤刺激性。

    Transdermal Preparation
    3.
    发明申请
    Transdermal Preparation 有权
    透皮制剂

    公开(公告)号：US20120058175A1

    公开(公告)日：2012-03-08

    申请号：US13318370

    申请日：2010-04-30

    申请人： Satoshi Amano ,  Tomohiro Shinoda ,  Natsumi Kase

    发明人： Satoshi Amano ,  Tomohiro Shinoda ,  Natsumi Kase

    IPC分类号： A61K9/70 ,  A61P25/28 ,  A61K31/15 ,  A61P9/12 ,  A61K9/00 ,  A61K31/138

    CPC分类号： A61K45/06 ,  A61K9/7084 ,  A61K31/138 ,  A61K31/15 ,  A61K2300/00

    摘要： Provided is a transdermal preparation, which is capable of long-term (1-day to 7-day) release of a basic drug from a preparation, continuously and at a consistent concentration; shows little reduction over time in the drug content, even if multiple drugs are contained in the preparation; and is produced by a simple process. The transdermal preparation comprises a substrate, and an adhesive layer containing a basic drug and a water-soluble polymer.

    摘要翻译： 提供一种透皮制剂，其能够以连续和一致的浓度从制剂中长期（1至7天）释放碱性药物; 即使制剂中含有多种药物，药物含量随时间推移几乎没有减少; 并通过简单的过程生产。 透皮制剂包括底物和含有碱性药物和水溶性聚合物的粘合剂层。

    Transdermal preparation
    4.
    发明授权
    Transdermal preparation 有权
    透皮制剂

    公开(公告)号：US08512742B2

    公开(公告)日：2013-08-20

    申请号：US13318370

    申请日：2010-04-30

    申请人： Satoshi Amano ,  Tomohiro Shinoda ,  Natsumi Kase

    发明人： Satoshi Amano ,  Tomohiro Shinoda ,  Natsumi Kase

    IPC分类号： A61K9/70

    CPC分类号： A61K45/06 ,  A61K9/7084 ,  A61K31/138 ,  A61K31/15 ,  A61K2300/00

    摘要： Provided is a transdermal preparation, which is capable of long-term (1-day to 7-day) release of a basic drug from a preparation, continuously and at a consistent concentration; shows little reduction over time in the drug content, even if multiple drugs are contained in the preparation; and is produced by a simple process. The transdermal preparation comprises a substrate, and an adhesive layer containing a basic drug and a water-soluble polymer.

    摘要翻译： 提供一种透皮制剂，其能够以连续和一致的浓度从制剂中长期（1至7天）释放碱性药物; 即使制剂中含有多种药物，药物含量随时间推移几乎没有减少; 并通过简单的过程生产。 透皮制剂包括底物和含有碱性药物和水溶性聚合物的粘合剂层。

    Transdermal preparation
    5.
    发明授权
    Transdermal preparation 有权

    公开(公告)号：US08475835B2

    公开(公告)日：2013-07-02

    申请号：US13318370

    申请日：2010-04-30

    申请人： Satoshi Amano ,  Tomohiro Shinoda ,  Natsumi Kase

    发明人： Satoshi Amano ,  Tomohiro Shinoda ,  Natsumi Kase

    IPC分类号： A61K9/70

    摘要： Provided is a transdermal preparation, which is capable of long-term (1-day to 7-day) release of a basic drug from a preparation, continuously and at a consistent concentration; shows little reduction over time in the drug content, even if multiple drugs are contained in the preparation; and is produced by a simple process. The transdermal preparation comprises a substrate, and an adhesive layer containing a basic drug and a water-soluble polymer.

    Transdermal absorption preparation
    6.
    发明授权
    Transdermal absorption preparation 有权
    透皮吸收制剂

    公开(公告)号：US08524273B2

    公开(公告)日：2013-09-03

    申请号：US12224586

    申请日：2007-02-27

    申请人： Satoshi Amano ,  Sachiko Honma ,  Tetsuro Tateishi ,  Natsumi Kase

    发明人： Satoshi Amano ,  Sachiko Honma ,  Tetsuro Tateishi ,  Natsumi Kase

    IPC分类号： A61K47/32 ,  A61K9/70 ,  A61K9/14 ,  A61K31/135 ,  A61F13/02

    CPC分类号： A61K9/7084 ,  A61K31/138 ,  A61K31/165

    摘要： A transdermal absorption preparation having a support and a pressure-sensitive adhesive layer consisting of multiple layers, wherein the pressure-sensitive adhesive layer comprises a drug-retaining layer containing a drug and an acrylic pressure-sensitive adhesive and a skin adhesion layer containing a styrene-isoprene-styrene block copolymer. This preparation can continuously release bisoprolol at a constant concentration. Moreover, it can be easily produced.

    摘要翻译： 一种具有支持体和由多层构成的压敏粘合剂层的透皮吸收制剂，其中所述压敏粘合剂层包含含药物的药物保持层和丙烯酸类压敏粘合剂以及含有苯乙烯的皮肤粘附层 - 异戊二烯 - 苯乙烯嵌段共聚物。 该制剂可以以恒定的浓度连续释放比索洛尔。 此外，它可以容易地生产。

    Transdermal Absorption Preparation
    7.
    发明申请
    Transdermal Absorption Preparation 有权
    经皮吸收制剂

    公开(公告)号：US20090068252A1

    公开(公告)日：2009-03-12

    申请号：US12224586

    申请日：2007-02-27

    申请人： Satoshi Amano ,  Sachiko Honma ,  Tetsuro Tateishi ,  Natsumi Kase

    发明人： Satoshi Amano ,  Sachiko Honma ,  Tetsuro Tateishi ,  Natsumi Kase

    IPC分类号： A61K9/70 ,  A61K47/32 ,  A61K31/138 ,  A61K31/166

    CPC分类号： A61K9/7084 ,  A61K31/138 ,  A61K31/165

    摘要： A transdermal absorption preparation having a support and a pressure-sensitive adhesive layer consisting of multiple layers, wherein the pressure-sensitive adhesive layer comprises a drug-retaining layer containing a drug and an acrylic pressure-sensitive adhesive and a skin adhesion layer containing a styrene-isoprene-styrene block copolymer. This preparation can continuously release bisoprolol at a constant concentration. Moreover, it can be easily produced.

    摘要翻译： 一种具有支持体和由多层构成的压敏粘合剂层的透皮吸收制剂，其中所述压敏粘合剂层包含含药物的药物保持层和丙烯酸类压敏粘合剂以及含有苯乙烯的皮肤粘附层 - 异戊二烯 - 苯乙烯嵌段共聚物。 该制剂可以以恒定的浓度连续释放比索洛尔。 此外，它可以容易地生产。

    Agent For Growing Fibroblasts
    10.
    发明申请
    Agent For Growing Fibroblasts 审中-公开
    用于生长成纤维细胞的药剂

    公开(公告)号：US20100316664A1

    公开(公告)日：2010-12-16

    申请号：US12867771

    申请日：2009-03-30

    申请人： Masato Iino ,  Satoshi Amano

    发明人： Masato Iino ,  Satoshi Amano

    IPC分类号： A61K8/99 ,  A61Q19/08 ,  A61Q19/00 ,  C12N5/077

    CPC分类号： A61Q19/08 ,  A61K8/97 ,  A61K8/99

    摘要： An agent for growing fibroblasts contains a yeast extract and a safflower extract as effective constituents. A method of growing fibroblasts comprises using a yeast extract and a safflower extract. An anti-aging agent for skin contains a yeast extract and a safflower extract as effective constituents.

    摘要翻译： 生长成纤维细胞的药剂含有酵母提取物和红花提取物作为有效成分。 培养成纤维细胞的方法包括使用酵母提取物和红花提取物。 皮肤抗衰老剂含有酵母提取物和红花提取物作为有效成分。