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13 条记录 (耗时 0.025 秒)

    Cephem compounds, and antibacterial agents
    4.
    发明授权
    Cephem compounds, and antibacterial agents 失效
    CEPHEM化合物和抗菌剂

    公开(公告)号：US5244892A

    公开(公告)日：1993-09-14

    申请号：US774844

    申请日：1991-10-11

    申请人： Seigo Suzue ,  Kikoh Obi ,  Tatsuhiro Saito ,  Keiji Hirai ,  Hideyuki Fukuda

    发明人： Seigo Suzue ,  Kikoh Obi ,  Tatsuhiro Saito ,  Keiji Hirai ,  Hideyuki Fukuda

    IPC分类号： C07D501/00 ,  C07D501/36

    CPC分类号： C07D501/00 ,  Y02P20/55

    摘要： Novel cephem compounds represented by a formula [I] and pharmacologically admissible salts or capable of physiologically hydrolyzable nontoxic esters thereof are disclosed. ##STR1## [wherein R.sup.1 indicates a straight-chain or branched lower alkyl group, which may be substituted by carboxyl group which may be protected, trityl group, hydrogen atom or fluorine-substituted lower alkyl group, R.sup.2 indicates a hydrogen atom, metal atom, protective group for carboxyl group or ester residue producible hydrolyzable ester in vivo, R.sup.3, R.sup.4, R.sup.5 and R.sup.6, which may be identical or different, indicate hydrogen atoms, halogen atoms, straight-chain or branched lower alkyl groups, which may be substituted, mercapto groups, which may be substituted, lower alkylamino groups, hydroxyl groups, which may be protected, lower alkoxy groups, lower alkanoyl groups, lower alkoxycarbonyl groups, or lower alkylenedioxy groups, which may be substituted, being maybe formed with R.sup.3 and R.sup.4, R.sup.7 indicates a hydrogen atom, cyano group, halogen atom or COOR.sup.8 (R.sup.8 is hydrogen or lower alkyl group), R.sup.9 indicates an amino group, which may be protected, Z indicates N or CH, and n indicates 0 or 1].Preparation processes for them and antibacterial agents containing them as effective ingredients are also claimed.

    8-alkoxyquinolonecarboxylic acid and salts thereof
    5.
    发明授权
    8-alkoxyquinolonecarboxylic acid and salts thereof 失效
    8-烷氧基喹诺酮羧酸及其盐

    公开(公告)号：US4980470A

    公开(公告)日：1990-12-25

    申请号：US3822

    申请日：1987-01-16

    申请人： Kuniyoshi Masuzawa ,  Seigo Suzue ,  Keiji Hirai ,  Takayoshi Ishizaki

    发明人： Kuniyoshi Masuzawa ,  Seigo Suzue ,  Keiji Hirai ,  Takayoshi Ishizaki

    IPC分类号： A61K31/47 ,  A61K31/495 ,  A61P31/04 ,  C07D215/56 ,  C07D401/04

    CPC分类号： C07D215/56 ,  C07D401/04

    摘要： Quinolonecarboxylic acid derivatives of the following formula: ##STR1## wherein R indicates a hydrogen atom or lower alkyl group, R.sup.1 indicates a lower alkyl group, R.sup.2 indicates a hydrogen atom, amino group or nitro group, X indicates a halogen atom, and Z indicates a halogen atom, piperazino group, N-methylpiperazino group, 3-methylpiperazino group, 3-hydroxypyrrolidino group, or pyrrolidino group of the following formula, ##STR2## (here, n is 0 or 1, R.sup.3 indicates a hydrogen atom or lower alkyl group, R.sup.4 indicates a hydrogen atom, lower alkyl group and R.sup.5 indicates a hydrogen atom, lower alkyl group, acyl group or alkoxycarbonyl group), the hydrates and pharmaceutically acceptable salts thereof are useful as antibacterial agents.

    摘要翻译： 下式的喹诺酮羧酸衍生物：其中R表示氢原子或低级烷基，R1表示低级烷基，R2表示氢原子，氨基或硝基，X表示卤素原子，Z表示 卤素原子，哌嗪子基，N-甲基哌嗪基，3-甲基哌嗪基，3-羟基吡咯烷子基或下式的吡咯烷子基（这里，n为0或1，R 3表示氢原子或低级烷基 基团，R4表示氢原子，低级烷基，R5表示氢原子，低级烷基，酰基或烷氧基羰基），其水合物及其药学上可接受的盐可用作抗菌剂。

    Editing system, computer, timing notice apparatus, computer program, and method for acquiring timing
    8.
    发明授权
    Editing system, computer, timing notice apparatus, computer program, and method for acquiring timing 失效
    编辑系统，计算机，定时通知装置，计算机程序和用于获取定时的方法

    公开(公告)号：US08200873B2

    公开(公告)日：2012-06-12

    申请号：US10799617

    申请日：2004-03-15

    申请人： Koji Tsukimori ,  Keiji Hirai

    发明人： Koji Tsukimori ,  Keiji Hirai

    IPC分类号： G06F13/36 ,  G06F13/362 ,  G06F1/04 ,  G06F1/12 ,  G06F15/16 ,  G06F13/42 ,  H04L5/00 ,  H04L7/00

    CPC分类号： G11B27/034 ,  G11B27/10 ,  G11B2220/90

    摘要： An editing system in which a personal computer is easily configured as an editing apparatus that performs editing processing in synchronization with predetermined timing. According to the invention, a personal computer 2 transmits an acquisition command C1 to a timing notice apparatus 4 over a USB cable 3, as a result, the personal computer 2 receives a timing notice signal S2 transmitted from the timing notice apparatus 4 under frame timing over the USB cable 3. Thus, it becomes possible to notify the personal computer 2 of the frame timing as reception timing of the timing notice signal S2 by connecting the timing notice apparatus 4 to the personal computer 2 over the USB cable 3 without the need of troublesome works such as installing a PCI board in a main body of the personal computer 2, thereby realizing an editing system 1 in which the personal computer 2 is easily configured as an editing apparatus that performs editing processing in synchronization with predetermined timing.

    摘要翻译： 一种编辑系统，其中个人计算机容易地配置为与预定定时同步地进行编辑处理的编辑装置。 根据本发明，个人计算机2通过USB电缆3将获取指令C1发送到定时通知装置4，结果，个人计算机2在帧定时下接收从定时通知装置4发送的定时通知信号S2 因此，可以通过USB电缆3将定时通知装置4连接到个人计算机2，而不需要通过个人计算机2将帧定时通知为定时通知信号S2的接收定时 诸如在个人计算机2的主体中安装PCI板的麻烦的工作，从而实现一个编辑系统1，其中个人计算机2被容易地配置为与预定定时同步地进行编辑处理的编辑装置。

    Quinolonecarboxylic acid derivatives and their preparation
    9.
    发明授权
    Quinolonecarboxylic acid derivatives and their preparation 失效
    喹诺酮羧酸衍生物及其制备方法

    公开(公告)号：US4894458A

    公开(公告)日：1990-01-16

    申请号：US233363

    申请日：1988-08-18

    申请人： Kuniyoshi Masuzawa ,  Seigo Suzue ,  Keiji Hirai ,  Takayoshi Ishizaki

    发明人： Kuniyoshi Masuzawa ,  Seigo Suzue ,  Keiji Hirai ,  Takayoshi Ishizaki

    IPC分类号： A61K31/47 ,  A61K31/495 ,  A61K31/55 ,  A61P31/04 ,  C07D215/56 ,  C07D401/04

    CPC分类号： C07D215/56 ,  C07D401/04

    摘要： Quinolonecarboxylic acid derivatives of the following formula, ##STR1## wherein R indicates straight or branched lower alkyl, R.sup.1 indicates cycloalkyl having 3 to 6 carbon atoms, straight or branched lower alkyl, halogenoalkyl, alkenyl, hydroxyalkyl, lower alkylamino or substituted or non-substituted phenyl, R.sup.2 indicates hydrogen, halogen, nitro or amino, X indicates halogen, Z indicates halogen, azetidino, pyrrolidino, piperidino, morpholino, thiomorpholino, piperazino or homopiperazino of the following formula, ##STR2## (here, n is 1 or 2, R.sup.3 indicates hydrogen, lower alkyl, lower acyl, acyloxycarbonyl or benzyl, R.sup.4 and R.sup.5 indicate hydrogen, lower alkyl, aminoalkyl, hydroxyalkyl or phenyl each independently), or pyrrolidino or piperidino of the following formula, ##STR3## (here, k is 0, 1 or 2, l is 0, 1 or 2, m is 0 or 1, R.sup.6 indicates hydrogen, lower alkyl or hydroxy, R.sup.7 indicates hydrogen, lower alkyl, halogenoalkyl or hydroxyalkyl, R.sup.8 indicates hydrogen, lower alkyl, lower acyl, alkoxycarbonyl or benzyl), the hydrates and pharmaceutically acceptable acid addition or alkali salts thereof are useful as antibacterial agents.

    摘要翻译： 下式的喹诺酮羧酸衍生物，其中R表示直链或支链的低级烷基，R1表示碳原子数为3〜6的环烷基，直链或支链的低级烷基，卤代烷基，链烯基，羟基烷基，低级烷基氨基或取代或未取代的 苯基，R 2表示氢，卤素，硝基或氨基，X表示卤素，Z表示卤素，氮杂环丁烷基，吡咯烷子基，哌啶子基，吗啉代，硫代吗啉代，哌嗪基或下式的高哌嗪基：（这里，n为1或2， R3表示氢，低级烷基，低级酰基，酰氧基羰基或苄基，R4和R5表示氢，低级烷基，氨基烷基，羟基烷基或苯基各自独立地），或下式的吡咯烷子基或哌啶子基，其中， ，1或2，l为0,1或2，m为0或1，R6表示氢，低级烷基或羟基，R7表示氢，低级烷基，卤代烷基或羟烷基，R8表示氢，低级烷基，低级酰基，烷氧基 羰基或苄基），其水合物及其药学上可接受的酸加成盐或碱盐可用作抗菌剂。