摘要:
A method for forming a porous implant suitable for a cavity from which tissue has been removed includes incorporating a gas or a pore forming agent into an alginate solution; transferring the alginate solution with the gas or the pore forming agent into a solidified body mold having a desired shape with an outer surface; removing the water from the solidified body; and subjecting the solidified body to a conversion solution to convert the outer surface to a less soluble alginate creating a composition comprising the outer surface having less soluble alginate and a core having more soluble alginate.
摘要:
A medical device includes a shaft having a distal end and a distal tip. An anchor mechanism is coupled to the distal end proximal to the distal tip. The anchor mechanism includes a rolled sheet of material and a sleeve located to surround the rolled sheet of material to maintain the rolled sheet of material in an initial rolled configuration, and is configured such that when the sleeve is retracted, the rolled sheet of material unrolls to expand radially to anchor the medical device.
摘要:
Devices and methods are provided for temporarily maintaining access to a body cavity in a targeted tissue region within a patient's body. A catheter for temporarily at least partially filing a body cavity in a targeted tissue region within a patient's body includes a shaft having a distal end, a proximal end, and a cavity filling member on a distal shaft section configured to at least partially fill the body cavity. A proximal shaft section is configured to be folded so as to be subcutaneously deployed within the patient when the cavity filling member is disposed within the body cavity so as to prevent intrusion of bacteria. An anti-bacterial material is applied to or incorporated within a surface of the shaft and the cavity filling member so as to prevent bacteria growth.
摘要:
An intracorporeal marker system includes a tissue marker pellet comprised of a polysaccharide material. The intracorporeal marker system may also include a fibrous marker of bioabsorbable fibers. In one embodiment, for example, an outer layer of bioabsorbable fibers is disposed around at least part of an inner core of bioabsorbable fibers.
摘要:
An intracorporeal marker delivery system includes a delivery device including a delivery cannula and a plunger. The delivery cannula has an inner lumen, a distal tip, and a discharge opening in communication with the inner lumen. A radiographically detectable marker having a fibrous-body and a radiographically detectable marker element coupled to the fibrous body is disposed within and pushable by the plunger through the inner lumen of the delivery cannula. An MRI detectable distal tip plug is disposed at least in part within a distal portion of the inner lumen distal to the radiographically detectable marker, and configured to partially occlude the discharge opening in the delivery cannula. An ultrasound detectable short term marker is interposed between the radiographically detectable marker and the MRI detectable distal tip plug in the inner lumen of the delivery cannula.
摘要:
A mass includes particles that exhibit an in vivo lifetime and that include a bioresorbable material and bubble cavities disposed in the particles, wherein the bubble cavities have length, width, and height dimensions at least one of which is less than or equal to about 2000 microns. The mass exhibits enhanced detectability by ultrasound energy during the lifetime; the lifetime begins upon exposure to in vivo fluids and ends between about 2 and about 20 weeks afterward; and a zero or non-zero fluid-to-solid ratio.
摘要:
A method for treating a site within a patient from which tissue has been removed includes providing at least one press-formed marker body formed of polysaccharide and a suitable binder; and placing the at least one of the press-formed marker body within the site where tissue has been removed so as to provide hemostasis therein.
摘要:
An intracorporeal marker includes a fibrous unitary marker body having bioabsorbable fibers compressed into a compressed configuration, and bound in the compressed configuration by a polymer binding agent. The intracorporeal marker may be incorporated into an intracorporeal marker delivery device having a delivery cannula which has a distal tip, an inner lumen and a discharge opening in communication with the inner lumen. The compression and binding occur prior to insertion of the fibrous unitary marker body into the inner lumen of the delivery cannula. The fibrous unitary marker body is slidably disposed within and pushable through the inner lumen of the elongated delivery cannula proximal to the discharge opening.
摘要:
A system for at least partially filling and marking a cavity within a patient includes a delivery device. A quantity of marker forming fluid is located within the delivery device. The quantity of marker forming fluid is configured to at least partially fill the cavity and form therein a bioabsorbable body after delivery into the cavity from the delivery device. A radiopaque marker, separate from the quantity of marker forming fluid and releasably attached to a portion of the delivery device, is configured to be delivered into the quantity of marker forming fluid in the cavity from the delivery device and configured to remain in the bioabsorbable body upon the formation of the bioabsorbable body in the cavity.
摘要:
The invention provides materials, devices and methods for marking biopsy sites for a limited time. The biopsy-marking materials are ultrasound-detectable bio-resorbable powders, with powder particles typically between about 20 microns and about 800 microns in maximum dimension, more preferably between about 300 microns and about 500 microns. The powders may be formed of polymeric materials containing cavities sized between about 10 microns and about 500 microns, and may also contain binding agents, anesthetic agents, hemostatic agents, and radiopaque markers. Devices for delivering the powders include tubes configured to contain the powders and to fit within a biopsy cannula, the powders being ejected by action of a syringe. Systems may include a tube containing powder, and a syringe containing sterile saline. The tube may be configured to fit within a biopsy cannula such as a Mammotome® or SenoCor 360™ cannula.