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1.发明授权公开(公告)号：US12085561B2
公开(公告)日：2024-09-10
申请号：US18186283
申请日：2023-03-20
申请人： Shahrzad Forouzanfar , Iman Khakpour , Nezih Pala , Chunlei Wang
发明人： Shahrzad Forouzanfar , Iman Khakpour , Nezih Pala , Chunlei Wang
IPC分类号： G01N33/543 , G01N27/30 , G01N27/327 , G01N33/574
CPC分类号： G01N33/5438 , G01N27/308 , G01N27/3276 , G01N33/57484 , G01N2333/49
摘要： Biosensors capable of detecting certain biomarkers (e.g., platelet-derived growth factor-BB (PDGF-BB)), as well as methods of fabricating the same and methods of using the same, are provided. The biosensors can be disposable and/or label-free. Electrochemical bipolar exfoliation can be used to exfoliate, reduce, and deposit (in a single step) graphene nanosheets on a desired substrate (e.g., an electrode). Affinity aptamers can be immobilized on the graphene nanosheets disposed on the substrate.
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公开(公告)号：US20230400456A1
公开(公告)日：2023-12-14
申请号：US18186283
申请日：2023-03-20
申请人： Shahrzad Forouzanfar , Iman Khakpour , Nezih Pala , Chunlei Wang
发明人： Shahrzad Forouzanfar , Iman Khakpour , Nezih Pala , Chunlei Wang
IPC分类号： G01N33/543 , G01N27/30 , G01N27/327 , G01N33/574
CPC分类号： G01N33/5438 , G01N27/308 , G01N27/3276 , G01N33/57484 , G01N2333/49
摘要： Biosensors capable of detecting certain biomarkers (e.g., platelet-derived growth factor-BB (PDGF-BB)), as well as methods of fabricating the same and methods of using the same, are provided. The biosensors can be disposable and/or label-free. Electrochemical bipolar exfoliation can be used to exfoliate, reduce, and deposit (in a single step) graphene nanosheets on a desired substrate (e.g., an electrode). Affinity aptamers can be immobilized on the graphene nanosheets disposed on the substrate.
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公开(公告)号：US20230400454A1
公开(公告)日：2023-12-14
申请号：US17806109
申请日：2022-06-09
申请人： Shahrzad Forouzanfar , Iman Khakpour , Nezih Pala , Chunlei Wang
发明人： Shahrzad Forouzanfar , Iman Khakpour , Nezih Pala , Chunlei Wang
IPC分类号： G01N33/543 , G01N33/574 , G01N27/30 , G01N27/327
CPC分类号： G01N33/5438 , G01N33/57484 , G01N27/308 , G01N27/3276 , G01N2333/49
摘要： Biosensors capable of detecting certain biomarkers (e.g., platelet-derived growth factor-BB (PDGF-BB)), as well as methods of fabricating the same and methods of using the same, are provided. The biosensors can be disposable and/or label-free. Electrochemical bipolar exfoliation can be used to exfoliate, reduce, and deposit (in a single step) graphene nanosheets on a desired substrate (e.g., an electrode). Affinity aptamers can be immobilized on the graphene nanosheets disposed on the substrate.
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公开(公告)号：US12130286B2
公开(公告)日：2024-10-29
申请号：US17806109
申请日：2022-06-09
申请人： Shahrzad Forouzanfar , Iman Khakpour , Nezih Pala , Chunlei Wang
发明人： Shahrzad Forouzanfar , Iman Khakpour , Nezih Pala , Chunlei Wang
IPC分类号： G01N33/543 , G01N27/30 , G01N27/327 , G01N33/574
CPC分类号： G01N33/5438 , G01N27/308 , G01N27/3276 , G01N33/57484 , G01N2333/49
摘要： Biosensors capable of detecting certain biomarkers (e.g., platelet-derived growth factor-BB (PDGF-BB)), as well as methods of fabricating the same and methods of using the same, are provided. The biosensors can be disposable and/or label-free. Electrochemical bipolar exfoliation can be used to exfoliate, reduce, and deposit (in a single step) graphene nanosheets on a desired substrate (e.g., an electrode). Affinity aptamers can be immobilized on the graphene nanosheets disposed on the substrate.
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公开(公告)号：US11605507B1
公开(公告)日：2023-03-14
申请号：US17839984
申请日：2022-06-14
摘要： Microsupercapacitors (MSCs), as well as methods of fabricating the same and methods of using the same, are provided. An MSC can include interdigitated microelectrodes having reduced graphene oxide (rGO) (e.g., vertically aligned nanosheets thereof) disposed on upper surfaces of the microelectrodes. The MSC can be fabricated by preparing a micro-current collector (MCC) comprising the interdigitated microelectrodes using photolithography and then performing a bipolar electrochemistry process on the MCC to deposit rGO on the upper surfaces of the interdigitated microelectrodes (e.g., in a single-step in situ exfoliation, reduction, and deposition).
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公开(公告)号：US12092536B1
公开(公告)日：2024-09-17
申请号：US18300745
申请日：2023-04-14
CPC分类号： G01L1/18 , A61B5/00 , A61B2562/0247 , A61B2562/0261 , A61B2562/12
摘要： The subject invention is concerned with systems and methods advantageously applying finite element analysis to establish design rules for a highly sensitive piezo-resistive pressure sensor with an output that is high enough to be detectable by simple and inexpensive circuits and therefore ensure wearability. Four frequently reported micro-feature shapes in micro-patterned piezo-resistive sensors are provided, where the micro-dome and micro-pyramid yield the highest sensitivity. Investigations of different conductivity values of micro-patterned elastomers show that coating the elastomer with a conductive material (e.g., a metallic coating) leads to higher current response when compared to composited conductive elastomers. Advantageous geometric parameters and spatial configurations of micro-pyramid design of piezo-resistive sensors are provided. Results show that an enhanced sensitivity and higher current output can be achieved by a lower spatial density configuration of three micro-features per millimeter length, a smaller feature size of around 100 μm, and a 60-50 degrees pyramid angle.
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公开(公告)号：US10940639B1
公开(公告)日：2021-03-09
申请号：US16775567
申请日：2020-01-29
申请人： Omena Okpowe , Nezih Pala , Chunlei Wang
发明人： Omena Okpowe , Nezih Pala , Chunlei Wang
IPC分类号： B29C64/124 , B29C64/129 , B29C64/135 , B29C64/165 , B29C64/314 , B29C64/35 , B29C64/188 , B33Y40/20 , B33Y10/00 , B33Y80/00 , B33Y40/10
摘要： Doped glass scintillators and methods of fabricating the same are provided. Doped glass scintillators can be fabricated by a stereolithography process, and doping can be carried out before the green body composite formation so that homogeneity of the dopant is improved. The structures retain an amorphous structure through the fabrication process, and the vacuum sintering process assists with keeping the dopants in their luminescence-producing oxidation state.
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公开(公告)号：US11737507B1
公开(公告)日：2023-08-29
申请号：US18050616
申请日：2022-10-28
摘要： Sensors, actuators, energy sources, and data processing for enabling artificial intelligent (AI) integrated automated features of intelligent electronic shoes are provided. The intelligent footwear can gather information from the shoe and send the data to a user interface for monitoring the physical activities of the wearer. A smart thermal actuation system can control the internal temperature of the shoe to offer a comfortable experience to the user. Intelligent footwear can also have systems for multipurpose sensing and actuation modules, which can use energy harvested by the user locomotion or by an energy source accompanied by artificial intelligence to gather and process information for ensuring an enhanced user experience.
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公开(公告)号：US11130283B2
公开(公告)日：2021-09-28
申请号：US17163823
申请日：2021-02-01
申请人： Omena Okpowe , Nezih Pala , Chunlei Wang
发明人： Omena Okpowe , Nezih Pala , Chunlei Wang
IPC分类号： B29C64/165 , B29C64/314 , B29C64/35 , B29C64/188 , B33Y40/10 , B33Y40/20 , B33Y10/00 , B33Y80/00 , C03C3/095 , C03C3/089 , G01T1/20 , C03B19/06
摘要： Doped glass scintillators and methods of fabricating the same are provided. Doped glass scintillators can be fabricated by a stereolithography process, and doping can be carried out before the green body composite formation so that homogeneity of the dopant is improved. The structures retain an amorphous structure through the fabrication process, and the vacuum sintering process assists with keeping the dopants in their luminescence-producing oxidation state.
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公开(公告)号：US10676357B1
公开(公告)日：2020-06-09
申请号：US16361332
申请日：2019-03-22
摘要： A single-step, in situ bipolar exfoliation system, and methods for exfoliations of multi-layer bulk black phosphorous into single-layer (two-dimensional), few-layer, or even nano-platelets phosphorene are provided. The bipolar exfoliation system can include: a first driving electrode; a second driving electrode electrically connected to the first driving electrode through an external power supply; at least one bipolar electrode comprising multi-layer bulk black phosphorous; and a solvent in physical contact with the first driving electrode, the second driving electrode, and the at least one bipolar electrode. The system can be configured such that the electric conditions between the first and second driving electrodes can be used to turn one end of the at least one bipolar electrode into an anodic pole and the other end of the at least one bipolar electrode into a cathodic pole such that the multi-layer black phosphorous is exfoliated into the single-layer, few-layer, or nano-platelets phosphorene.
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