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1.发明申请Antimicrobial, Radiopaque, Microfiber-Reinforced, Polymeric Methacrylate Bone Cement 有权抗菌，不透射线，超细纤维增强聚合甲基丙烯酸酯骨水泥公开(公告)号：US20100152319A1
公开(公告)日：2010-06-17
申请号：US12223211
申请日：2007-02-06
IPC分类号： A61F2/28
CPC分类号： A61K9/5026
摘要： An methacrylate bone cement is toughened and rendered radiopaque by reinforcing with electrospun microfibers including a radiopacifier and antimicrobial agents to provide a bone cement for use in repairing bone or other hard tissues.
摘要翻译： 通过用包括放射性增透剂和抗微生物剂在内的电纺丝微纤维进行增强，使甲基丙烯酸酯骨水泥硬化并变得不透射线，以提供用于修复骨或其它硬组织的骨粘固剂。
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公开(公告)号：US08507614B2
公开(公告)日：2013-08-13
申请号：US12322841
申请日：2009-02-07
IPC分类号： C08G63/91
CPC分类号： A61B17/72 , A61B17/7258 , A61B17/866 , A61B2017/00004 , A61B2017/00557 , A61L31/06 , A61L31/148 , C08L67/04 , C08L2666/18
摘要： Absorbable, multiphasic, crystalline, solid blend compositions having at least two first order thermal transitions, are formed of a segmented l-lactide copolymer as the principal or major component and at least one additional crystalline thermoplastic absorbable polyester having glycolide-based sequences, a fraction of which participated in ester-ester interchange reactions with lactide-based sequences to produce crystalline materials with modulated properties for use in producing orthopedic and tissue-repair devices.
摘要翻译： 具有至少两个一级热转变的可吸收的，多相的，结晶的，固体共混物组合物由分段的l-丙交酯共聚物作为主要或主要组分形成，以及至少一种另外的结晶热塑性可吸收聚酯，其具有基于乙交酯的序列， 其中参与与基于丙交酯的序列的酯 - 酯交换反应以产生具有用于生产矫形和组织修复装置的调制性质的结晶材料。
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3.发明授权Antimicrobial, radiopaque, microfiber-reinforced, polymeric methacrylate bone cement 有权抗菌，不透射线，超细纤维增强，聚合甲基丙烯酸酯骨水泥公开(公告)号：US07981945B2
公开(公告)日：2011-07-19
申请号：US12223211
申请日：2007-02-06
IPC分类号： A61F2/00
CPC分类号： A61K9/5026
摘要： An methacrylate bone cement is toughened and rendered radiopaque by reinforcing with electrospun microfibers including a radiopacifier and antimicrobial agents to provide a bone cement for use in repairing bone or other hard tissues.
摘要翻译： 通过用包括放射性增透剂和抗微生物剂在内的电纺丝微纤维进行增强，使甲基丙烯酸酯骨水泥硬化并变得不透射线，以提供用于修复骨或其它硬组织的骨粘固剂。
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公开(公告)号：US20090204116A1
公开(公告)日：2009-08-13
申请号：US12322841
申请日：2009-02-07
CPC分类号： A61B17/72 , A61B17/7258 , A61B17/866 , A61B2017/00004 , A61B2017/00557 , A61L31/06 , A61L31/148 , C08L67/04 , C08L2666/18
摘要： Absorbable, multiphasic, crystalline, solid blend compositions having at least two first order thermal transitions, are formed of a segmented l-lactide copolymer as the principal or major component and at least one additional crystalline thermoplastic absorbable polyester having glycolide-based sequences, a fraction of which participated in ester-ester interchange reactions with lactide-based sequences to produce crystalline materials with modulated properties for use in producing orthopedic and tissue-repair devices.
摘要翻译： 具有至少两个一级热转变的可吸收的，多相的，结晶的，固体共混物组合物由分段的l-丙交酯共聚物作为主要或主要组分形成，以及至少一种另外的结晶热塑性可吸收聚酯，其具有基于乙交酯的序列， 其中参与与基于丙交酯的序列的酯 - 酯交换反应以产生具有用于生产矫形和组织修复装置的调制性质的结晶材料。
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公开(公告)号：US20130272997A1
公开(公告)日：2013-10-17
申请号：US13445855
申请日：2012-04-12
IPC分类号： A61K31/765 , A61K31/65 , A61K31/7036 , A61K38/14 , A61K31/407 , A61P29/00 , A61P31/04 , A61P37/06 , A61P37/04 , A61P23/00 , A61P17/02 , A61P35/00 , A61P7/04 , A61K47/34 , A61P19/08 , A61K33/42 , A61P31/00 , A61K38/39 , C08G64/18 , A61K31/7056
CPC分类号： A61K31/765 , A61K31/166 , A61K31/407 , A61K31/65 , A61K31/7036 , A61K31/7048 , A61K31/7056 , A61K33/42 , A61K38/14 , A61K38/39 , A61K45/06 , A61L24/0015 , A61L24/0042 , A61L24/046 , A61L2300/404 , A61L2400/04 , C08G63/64 , C08G64/18 , C08L67/04
摘要： A biocompatible, polymeric composition is disclosed. The composition comprises a base polymer comprising (i) a prepolymer comprising para-dioxanone (PDO) and trimethylene carbonate (TMC); and (ii) an end-graft polymer chain comprising a polylactone. Also disclosed are a method for treating bleeding from bone or bony structures using the composition, a method for filling a void or correct a defect in a bone using the composition, and a method for producing the biocompatible, polymeric composition of the present application.
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6.发明授权公开(公告)号：US08858980B2
公开(公告)日：2014-10-14
申请号：US13445855
申请日：2012-04-12
CPC分类号： A61K31/765 , A61K31/166 , A61K31/407 , A61K31/65 , A61K31/7036 , A61K31/7048 , A61K31/7056 , A61K33/42 , A61K38/14 , A61K38/39 , A61K45/06 , A61L24/0015 , A61L24/0042 , A61L24/046 , A61L2300/404 , A61L2400/04 , C08G63/64 , C08G64/18 , C08L67/04
摘要： A biocompatible, polymeric composition is disclosed. The composition comprises a base polymer comprising (i) a prepolymer comprising para-dioxanone (PDO) and trimethylene carbonate (TMC); and (ii) an end-graft polymer chain comprising a polylactone. Also disclosed are a method for treating bleeding from bone or bony structures using the composition, a method for filling a void or correct a defect in a bone using the composition, and a method for producing the biocompatible, polymeric composition of the present application.
摘要翻译： 公开了生物相容的聚合物组合物。 该组合物包含基础聚合物，其包含（i）包含对二恶烷酮（PDO）和三亚甲基碳酸酯（TMC）的预聚物; 和（ii）包含聚内酯的端基接枝聚合物链。 还公开了使用该组合物治疗骨或骨结构出血的方法，使用该组合物填充空隙或校正骨中缺陷的方法，以及本申请的生物相容性聚合物组合物的制备方法。
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