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公开(公告)号：US4560413A
公开(公告)日：1985-12-24
申请号：US612299
申请日：1984-05-21
申请人： Shigehide Takagi , Norio Yokota , Syohei Sato , Toshihiro Nishi
发明人： Shigehide Takagi , Norio Yokota , Syohei Sato , Toshihiro Nishi
CPC分类号： C04B7/3453 , C04B28/02 , Y02P40/148
摘要： A hardened cement material having enhanced flexural strength, heat resistance, and water resistance prepared from a cement composition comprising 100 parts by weight of a hydraulic cement material containing .gamma.-dicalcium silicate (.gamma.-C.sub.2 S) preferably in an amount of 1% by weight or more and 1 to 20 parts by weight of a water-dispersible polymeric material, and mixed with 5 to 25 parts by weight of water, by a molding procedure and by a heat-hardening procedure at a temperature of from 40.degree. C. to 180.degree. C. while controlling the relative humidity to 20% to 70% and/or applying a pressure of 5 to 15 atmospheres.
摘要翻译： 一种具有增强的抗弯强度，耐热性和耐水性的硬化水泥材料，其由水泥组合物制备，该水泥组合物包含100重量份含有γ-硅酸二钙 更多和1至20重量份的水分散性聚合物材料，并通过模制步骤和通过加热硬化程序在40℃至180℃的温度下与5至25重量份的水混合 同时将相对湿度控制在20％至70％和/或施加5至15个大气压的压力。
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公开(公告)号：US5211661A
公开(公告)日：1993-05-18
申请号：US570997
申请日：1990-08-22
申请人： Kiyoshi Shinjou , Shigehide Takagi
发明人： Kiyoshi Shinjou , Shigehide Takagi
CPC分类号： A61F2/28 , A61L27/34 , A61F2002/30093 , A61F2002/30968 , A61F2210/0019 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00203
摘要： An artificial living body composite material comprising an artificial bone portion formed to a desired shape and size, and an inclusion membrane comprising an organic polymer material as a main constituent; optionally the artificial bone portion being composed of a base member and a coating layer.
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3.发明授权Ceramic device providing an environment for the promotion and formation of new bone 失效陶瓷器件为促进和形成新骨骼提供了一个环境
公开(公告)号：US5531794A
公开(公告)日：1996-07-02
申请号：US305440
申请日：1994-09-13
申请人： Shigehide Takagi , Kuniomi Ito , Tsuneo Hidaka
发明人： Shigehide Takagi , Kuniomi Ito , Tsuneo Hidaka
CPC分类号： A61F2/28 , A61L27/12 , A61L27/56 , A61F2002/30011 , A61F2002/30224 , A61F2002/30261 , A61F2002/30785 , A61F2002/30968 , A61F2230/0069 , A61F2230/0082 , A61F2250/0023 , A61F2310/00293
摘要： A ceramic device providing an environment for the promotion and formation of new bone. The ceramic device is made of a sinter of calcium phosphate compound, containing a plurality of perfect spherical pores whose diameter ranges from 10-450 .mu.m to provide a suitable environment for the formation of new bone. A plurality of micro pores is included whose diameter ranges from 0.01-0.5 .mu.m which surrounds the perfect spherical pores to interconnect the perfect spherical pores with an outer surface of the ceramic device with the micro pores interconnecting with each other.
摘要翻译： 陶瓷器件为促进和形成新骨骼提供了环境。 陶瓷装置由磷酸钙化合物的烧结体制成，含有多个直径范围为10-450μm的完美球形孔，为新骨形成提供了合适的环境。 包括多个微孔，其直径范围为0.01-0.5μm，其围绕完美的球形孔，以使完美的球形孔与陶瓷装置的外表面互相互相连接。
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公开(公告)号：US4654314A
公开(公告)日：1987-03-31
申请号：US628600
申请日：1984-07-06
申请人： Shigehide Takagi , Shigeru Yamauchi
发明人： Shigehide Takagi , Shigeru Yamauchi
CPC分类号： A61L27/12 , A61L27/56 , C04B38/065 , C04B38/106 , A61F2310/00293 , A61L2400/18 , C04B2111/00836 , C04B2111/00844
摘要： A porous ceramic material composed of a sintered porous body of a calcium phosphate compound is described. A multiplicity of capillary void paths having a diameter of 1 to 30 .mu.m and a multiplicity of pores having a diameter of 1 to 600 .mu.m are formed in the sintered porous body. At least part of the pores are connected to the exterior space of the sintered porous body through at least a part of the capillary voids. The porous ceramic material is valuable as a medical material, e.g., a substitute or prosthesis for bone or dental root, and also an electronic material and a genetic engineering material.When the porous ceramic material is embedded in a bone defect of human or animals, osteolytic cells, osteoblasts, erythrocytes and body fluid are selectively allowed to intrude through the porous ceramic material while almost no intrusion of osteoclasts and collagen fibers is allowed. Accordingly, the porous ceramic material can be utilized for inducing new-born bone, controlling resorption of bone with age, remedying bone defects.
摘要翻译： 描述了由磷酸钙化合物的烧结多孔体组成的多孔陶瓷材料。 在烧结多孔体中形成直径为1〜30μm的多个毛细管空隙路径和多个直径为1〜600μm的孔。 孔的至少一部分通过毛细孔隙的至少一部分连接到烧结多孔体的外部空间。 多孔陶瓷材料作为医疗材料是有价值的，例如用于骨或牙根的替代物或假体，以及电子材料和遗传工程材料。 当多孔陶瓷材料嵌入人或动物的骨缺损中时，选择性地允许溶骨细胞，成骨细胞，红细胞和体液侵入多孔陶瓷材料，同时几乎不允许破骨细胞和胶原纤维的侵入。 因此，多孔陶瓷材料可用于诱导新生骨，控制骨龄随着年龄的吸收，修复骨缺损。
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公开(公告)号：US5141510A
公开(公告)日：1992-08-25
申请号：US460054
申请日：1990-02-14
CPC分类号： A61F2/28 , A61L27/12 , A61F2002/30785 , A61F2002/30968 , A61F2310/00293
摘要： There is provided a structure of artificial bone for use in implanting or grafting bone comprising; a sintered body of calcium phosphate compounds; and hollowed minute tubes in said sintered body, having very small diameter, and extending along with a direction of Haversian canal extension of live organism, so as to produce two dimensional close-packed structure in said body, in form of cubic or hexagonal arrangement. The arrangement has in the sintered body of calcium phosphate compounds; hollowed minute tubes having a diameter of 0.1 to 2.0 mm, and the major portions thereof extending along with a direction of the Haversian canal extension, and producing a two dimensional close packed arrangement in said body against the face vertical to said direction, and being arranged with a separation, distance of 1.0 to 5.0 mm. The structure has preferably really spherical pores having diameter of 50 to 600 micrometer, and the porosity thereof being 0.5 to 40 percent.
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6.发明授权Sintered alumina article with high flexural strength and process for producing same 失效具有高弯曲强度的烧结氧化铝制品及其制造方法
公开(公告)号：US4996177A
公开(公告)日：1991-02-26
申请号：US222976
申请日：1988-07-22
申请人： Shigehide Takagi , Hideo Yano , Takashi Oku , Keijiro Shigeru , Yoshifumi Kuboto , Tsutomu Shishikura
发明人： Shigehide Takagi , Hideo Yano , Takashi Oku , Keijiro Shigeru , Yoshifumi Kuboto , Tsutomu Shishikura
IPC分类号： C04B35/10 , C04B35/111
CPC分类号： C04B35/111 , Y10T428/24132
摘要： A sintered alumina article having an excellent flexural strength comprises numerous sintered plate crystalline corundum particles each having cleavage surface planes and accumulated on and bonded to each other in a manner such that the cleavage surface planes of the accumulated plate crystalline particles are substantially in parallel to each other and can be produced by forming the plate crystalline corundum particles into a predetermined shape so that the plate crystalline particles are accumulated in the above-mentioned manner; and by sintering the resultant precursory article at 1500.degree. C. or more under the ambient atmospheric pressure.
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公开(公告)号：US4963145A
公开(公告)日：1990-10-16
申请号：US325098
申请日：1989-03-20
申请人： Shigehide Takagi , Shigeru Yamauchi
发明人： Shigehide Takagi , Shigeru Yamauchi
CPC分类号： A61L27/12 , A61L27/56 , C04B38/065 , C04B38/106 , A61F2310/00293 , A61L2400/18 , C04B2111/00836 , C04B2111/00844
摘要： A porous ceramic material composed of a sintered porous body of a calcium phosphate compound is described. A multiplicity of capillary void paths having a diameter of 1 to 30 .mu.m and a multiplicity of pores having a diameter of 1 to 600 .mu.m are formed in the sintered porous body. At least part of the pores are connected to the exterior space of the sintered porous body through at least a part of the capillary voids. The porous ceramic material is valuable as a medical material, e.g., a substitute or prosthesis for bone or dental root, and also an electronic material and a genetic engineering material.When the porous ceramic material is embedded in a bone defect of human or animals, osteolytic cells, osteoblasts, erythrocytes and body fluid are selectively allowed to intrude through the porous ceramic material while almost no intrusion of osteoclasts and collagen fibers is allowed. Accordingly, the porous ceramic material can be utilized for inducing new-born bone, controlling resorption of bone with age, remedying bone defects.
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