公开(公告)号：US4805439A

公开(公告)日：1989-02-21

申请号：US094405

申请日：1987-09-08

申请人： Shigeo Kobayashi ,  Osamu Yoshida ,  Haruo Saito ,  Tsutomu Shigeta ,  Hiroshi Nara ,  Shinji Abe ,  Kiyoharu Yamamoto

发明人： Shigeo Kobayashi ,  Osamu Yoshida ,  Haruo Saito ,  Tsutomu Shigeta ,  Hiroshi Nara ,  Shinji Abe ,  Kiyoharu Yamamoto

IPC分类号： B21D5/02 ,  B21D11/22

CPC分类号： B21D5/02 ,  Y10S72/701

摘要： A work following device for controlling the movement of the free portion of a work during a press working process such as a bending press working process to prevent the free portion of the work from warping due to the inertia thereof in the final stage of the press working process and for restoring the work to its initial position after the same has been pressed. The work following device having a base plate mounted with the components, a drum case fixedly disposed on the base plate and rotatably housing a drum, an electromagnet which holds to the free portion of a work during the press working process, an electromagnet holding member, a positioning block which positions the electromagnet holding member at a predetermined seating position at the start of the work following operation, an elongate spring plate having one end fixed to the drum and the other end fixed to the electromagnet holding member, and wound on the drum, a clutch connecting the drum to and disconnecting the drum from a reduction gear which is driven by a motor, and a control unit for controlling the operation of the components in accordance with a control program.

摘要翻译： 一种工件跟随装置，用于在冲压加工过程如压弯加工过程中控制工件的自由部分的移动，以防止工件的自由部分在压力加工的最后阶段由于其惯性而翘曲 过程，并将工作恢复到初始位置，同时被压制。 工件跟随装置具有安装有部件的基板，固定地设置在基板上并可旋转地容纳滚筒的滚筒壳体，在冲压加工过程中保持到工件的自由部分的电磁体，电磁体保持部件， 定位块，其将电磁体保持构件定位在开始工作开始时的预定就座位置;细长弹簧板，其一端固定到滚筒，另一端固定到电磁体保持构件，并缠绕在滚筒上 ，将滚筒与由马达驱动的减速齿轮连接到滚筒并将其分离的离合器，以及用于根据控制程序控制部件的操作的控制单元。

公开(公告)号：US08322862B2

公开(公告)日：2012-12-04

申请号：US12848309

申请日：2010-08-02

申请人： Hiroshi Nara

发明人： Hiroshi Nara

IPC分类号： G03B21/14

CPC分类号： H04N9/3185 ,  H04N9/317 ,  H04N9/3194

摘要： A projector includes: a storing unit that stores setting data indicating a manual trapezoidal distortion correction system selected out of plural kinds of manual trapezoidal distortion correction systems; an operation unit that generates operation information; an imaging unit that picks up an image of a projection target area and generates a pickup image; an automatic trapezoidal distortion correction unit that performs automatic trapezoidal distortion correction; a projecting unit that projects, after the automatic trapezoidal distortion correction is performed, irrespectively of the manual trapezoidal distortion correction system indicated by the setting data, an adjustment instruction image for urging adjustment of a vertex position of a display planned area of the image in the projection target area; and a manual trapezoidal distortion correction unit that performs manual trapezoidal distortion correction on the basis of operation information indicating an adjustment instruction for the vertex position.

摘要翻译： 投影机包括：存储单元，存储指示从多种手动梯形失真校正系统中选择的手动梯形失真校正系统的设置数据; 生成操作信息的操作单元; 成像单元，其拾取投影对象区域的图像并生成拾取图像; 自动梯形失真校正单元，执行自动梯形失真校正; 投影单元，在执行自动梯形失真校正之后，与由设置数据指示的手动梯形失真校正系统无关地投影，用于促使在图像的显示计划区域的顶点位置的调整的调整指令图像 投影目标区域; 以及手动梯形失真校正单元，其基于指示用于顶点位置的调整指令的操作信息执行手动梯形失真校正。

公开(公告)号：US20080027050A1

公开(公告)日：2008-01-31

申请号：US11579298

申请日：2005-04-28

申请人： Jun Terauchi ,  Haruhiko Kuno ,  Hiroshi Nara ,  Hideyuki Oki ,  Kenjiro Sato

发明人： Jun Terauchi ,  Haruhiko Kuno ,  Hiroshi Nara ,  Hideyuki Oki ,  Kenjiro Sato

IPC分类号： A61K31/517 ,  A61K31/519 ,  A61K31/5377 ,  A61P19/02 ,  C07D239/90 ,  C07D401/12 ,  C07D405/14 ,  C07D409/14 ,  C07D413/12 ,  C07D487/04 ,  C07D495/04 ,  C07D498/04

CPC分类号： C07D495/04 ,  C07D217/26 ,  C07D239/90 ,  C07D401/12 ,  C07D405/12 ,  C07D405/14 ,  C07D409/14 ,  C07D413/12 ,  C07D413/14 ,  C07D471/04 ,  C07D487/04 ,  C07D491/04

摘要： The present invention provides a novel amide derivative having a matrix metalloproteinase inhibitory activity, and useful as a pharmaceutical agent, which is a compound represented by the formula (I) wherein ring A is an optionally substituted, nitrogen-containing heterocycle, ring B is an optionally substituted monocyclic homocycle or an optionally substituted monocyclic heterocycle, Z is N or NR1 (R1 is a hydrogen atom or an optionally substituted hydrocarbon group), is a single bond or a double bond, R2 is a hydrogen atom or an optionally substituted hydrocarbon group, X is an optionally substituted spacer having 1 to 6 atoms, ring C is (1) an optionally substituted homocycle or (2) an optionally substituted heterocycle other than a ring represented by (II) (X′ is S, O, SO, or CH2), and at least one of ring B and ring C has substituent(s), provided that N-{(1S,2R)-1-(3,5-difluorobenzyl)-3-[(3-ethylbenzyl)amino]-2-hydroxypropyl}-5,6-dimethyl-4-oxo-1,4-dihadrothieno[2,3-d]pyrimidine-2-carboxamide is excluded, or a salt thereof.

摘要翻译： 本发明提供一种具有基质金属蛋白酶抑制活性的新型酰胺衍生物，可用作药剂，其为式（I）表示的化合物，其中环A为任选取代的含氮杂环，环B为 任选取代的单环同位素或任选取代的单环杂环，Z是N或NR 1（R 1是氢原子或任选取代的烃基），是单键 或双键，R 2是氢原子或任选取代的烃基，X是任选取代的具有1-6个原子的间隔基，环C是（1）任选取代的杂环或（2 ）除（II）表示的环以外的任选取代的杂环（X'为S，O，SO或CH 2 2），和至少一个 环B和环C具有取代基，条件是N - {（1S，2R）-1-（3,5-二氟苄基）-3 - [（3-乙基苄基）氨基] -2-羟丙基} -5 ，6-二甲基-4-氧代-1,4-二氢噻吩并[2,3-d]嘧啶-2-甲酰胺或其盐。

公开(公告)号：USD479524S1

公开(公告)日：2003-09-09

申请号：US29169976

申请日：2002-10-29

申请人： Hiroshi Nara

设计人： Hiroshi Nara

公开(公告)号：US08328366B2

公开(公告)日：2012-12-11

申请号：US12843993

申请日：2010-07-27

申请人： Hiroshi Nara

发明人： Hiroshi Nara

IPC分类号： G03B21/14 ,  H04N3/23 ,  H04N7/12 ,  G06K9/40

CPC分类号： H04N5/2353 ,  H04N9/3185 ,  H04N9/3194

摘要： A projector includes: a projecting unit that projects a first image on a projection target area; an imaging unit that picks up a first pickup image of the projection target area during the projection of the first image and picks up a second pickup image of the projection target area during single-color image projection or during non-projection with automatic exposure; an imaging control unit that changes an exposure setting value on the basis of the first pickup image and an exposure setting value during the last imaging and causes the imaging unit to pick up an image of the projection target area during the projection of the first image at the exposure setting value after the change and regenerate the first pickup image; a first coordinate information generating unit that generates first coordinate information; and a second coordinate information generating unit that generates second coordinate information.

摘要翻译： 投影机包括：投影单元，其将第一图像投影在投影对象区域上; 成像单元，其在第一图像的投影期间拾取投影对象区域的第一拾取图像，并且在单色图像投影期间或在非自动曝光的非投影期间拾取投影对象区域的第二拾取图像; 成像控制单元，其在上次成像期间根据第一拍摄图像和曝光设定值改变曝光设定值，并且使得成像单元在第一图像的投影期间拾取投影对象区域的图像 改变之后的曝光设定值，并重新生成第一拾取图像; 产生第一坐标信息的第一坐标信息生成单元; 以及产生第二坐标信息的第二坐标信息生成单元。

公开(公告)号：US20110032492A1

公开(公告)日：2011-02-10

申请号：US12848309

申请日：2010-08-02

申请人： Hiroshi Nara

发明人： Hiroshi Nara

IPC分类号： G03B21/14

CPC分类号： H04N9/3185 ,  H04N9/317 ,  H04N9/3194

摘要： A projector includes: a storing unit that stores setting data indicating a manual trapezoidal distortion correction system selected out of plural kinds of manual trapezoidal distortion correction systems; an operation unit that generates operation information; an imaging unit that picks up an image of a projection target area and generates a pickup image; an automatic trapezoidal distortion correction unit that performs automatic trapezoidal distortion correction; a projecting unit that projects, after the automatic trapezoidal distortion correction is performed, irrespectively of the manual trapezoidal distortion correction system indicated by the setting data, an adjustment instruction image for urging adjustment of a vertex position of a display planned area of the image in the projection target area; and a manual trapezoidal distortion correction unit that performs manual trapezoidal distortion correction on the basis of operation information indicating an adjustment instruction for the vertex position.

摘要翻译： 投影机包括：存储单元，存储指示从多种手动梯形失真校正系统中选择的手动梯形失真校正系统的设置数据; 生成操作信息的操作单元; 成像单元，其拾取投影对象区域的图像并生成拾取图像; 自动梯形失真校正单元，执行自动梯形失真校正; 投影单元，在执行自动梯形失真校正之后，与设置数据所指示的手动梯形失真校正系统无关地投影，用于促使在图像的显示计划区域的顶点位置的调整的调整指示图像 投影目标区域; 以及手动梯形失真校正单元，其基于指示用于顶点位置的调整指令的操作信息执行手动梯形失真校正。

公开(公告)号：US20090013082A1

公开(公告)日：2009-01-08

申请号：US11903572

申请日：2007-09-24

申请人： Hiroshi Nara

发明人： Hiroshi Nara

IPC分类号： G06F15/16

CPC分类号： G05B15/02

摘要： A transmitting section spontaneously transmits a command including device information relating to a field device, to a field server. An updating section receives commands including device information which is spontaneously transmitted from field devices, and updates a database on the basis of the device information. Based on the device information stored in the database, a server communicating section communicates with the field devices.

摘要翻译： 发送部将自动发送包括与现场设备有关的设备信息的命令发送到现场服务器。 更新部分接收包括从现场设备自发发送的设备信息的命令，并且基于设备信息来更新数据库。 基于存储在数据库中的设备信息，服务器通信部分与现场设备通信。

公开(公告)号：US09212149B2

公开(公告)日：2015-12-15

申请号：US11579298

申请日：2005-04-28

申请人： Jun Terauchi ,  Hiroshi Nara ,  Hideyuki Oki ,  Kenjiro Sato

发明人： Jun Terauchi ,  Hiroshi Nara ,  Hideyuki Oki ,  Kenjiro Sato

IPC分类号： C07D239/90 ,  C07D487/04 ,  C07D491/04 ,  C07D495/04 ,  C07D471/04 ,  C07D217/26 ,  C07D401/12 ,  C07D405/12 ,  C07D405/14 ,  C07D409/14 ,  C07D413/14

CPC分类号： C07D495/04 ,  C07D217/26 ,  C07D239/90 ,  C07D401/12 ,  C07D405/12 ,  C07D405/14 ,  C07D409/14 ,  C07D413/12 ,  C07D413/14 ,  C07D471/04 ,  C07D487/04 ,  C07D491/04

摘要： The present invention provides a novel amide derivative having a matrix metalloproteinase inhibitory activity, and useful as a pharmaceutical agent, which is a compound represented by the formula (I) wherein ring A is an optionally substituted, nitrogen-containing heterocycle, ring B is an optionally substituted monocyclic homocycle or an optionally substituted monocyclic heterocycle, Z is N or NR1 (R1 is a hydrogen atom or an optionally substituted hydrocarbon group), is a single bond or a double bond, R2 is a hydrogen atom or an optionally substituted hydrocarbon group, X is an optionally substituted spacer having 1 to 6 atoms, ring C is (1) an optionally substituted homocycle or (2) an optionally substituted heterocycle other than a ring represented by (II) (X′ is S, O, SO, or CH2), and at least one of ring B and ring C has substituent(s), provided that N-{(1S,2R)-1-(3,5-difluorobenzyl)-3-[(3-ethylbenzyl)amino]-2-hydroxypropyl}-5,6-dimethyl-4-oxo-1,4-dihadrothieno[2,3-d]pyrimidine-2-carboxamide is excluded, or a salt thereof.

摘要翻译： 本发明提供一种具有基质金属蛋白酶抑制活性的新型酰胺衍生物，可用作药剂，其为式（I）表示的化合物，其中环A为任选取代的含氮杂环，环B为 任选取代的单环同位素或任选取代的单环杂环，Z是N或NR1（R1是氢原子或任选取代的烃基），是单键或双键，R2是氢原子或任选取代的烃基 X为任选取代的具有1-6个原子的间隔基，环C为（1）任选取代的杂环，或（2）除（II）表示的环以外的任选取代的杂环（X'为S，O，SO， 或CH 2），并且环B和环C中的至少一个具有取代基，条件是N - {（1S，2R）-1-（3,5-二氟苄基）-3 - [（3-乙基苄基）氨基 ] -2-羟丙基} -5,6-二甲基-4-氧代-1,4-二氢噻吩并[2,3-d]嘧啶 -2-甲酰胺或其盐。

公开(公告)号：US06953789B2

公开(公告)日：2005-10-11

申请号：US10757325

申请日：2004-01-13

申请人： Toshiro Yamashita ,  Hiroshi Nara ,  Masayuki Takizawa ,  Koji Yoshimura

发明人： Toshiro Yamashita ,  Hiroshi Nara ,  Masayuki Takizawa ,  Koji Yoshimura

IPC分类号： A61P19/02 ,  A61P19/10 ,  C07D207/26 ,  C07D207/273 ,  C07D207/40 ,  C07D207/416 ,  C07D209/48 ,  C07D211/76 ,  C07D211/78 ,  C07D211/88 ,  C07D401/12 ,  C07D403/12 ,  C07D405/06 ,  C07D405/12 ,  C07D409/12 ,  C07D223/10 ,  A61K31/4025 ,  A61K31/55 ,  C07D207/50

CPC分类号： C07D207/273 ,  C07D207/40 ,  C07D207/416 ,  C07D209/48 ,  C07D211/76 ,  C07D211/78 ,  C07D211/88 ,  C07D401/12 ,  C07D403/12 ,  C07D405/06 ,  C07D405/12 ,  C07D409/12

摘要： The present invention provides a compound represented by Formula: wherein ring A and ring B may be same or different and each is an optionally substituted homocyclic or heterocyclic ring and the like, each R1 may be same or different and is a hydrogen atom, an optionally substituted hydrocarbon group, an acyl group, an optionally substituted heterocyclic group or SR2, etc., X1 is a bond, an optionally substituted divalent C1-3 aliphatic hydrocarbon group or —NR3—, etc, X2 is a bond, an optionally substituted divalent C1-3 aliphatic hydrocarbon group, —NR4—, —O— or —S(O)p— (wherein p is 0, 1 or 2), each Y may be same or different and is a hydrogen atom, an optionally substituted hydrocarbon group, a halogen atom, a carboxyl group, an acyl group, an optionally substituted hydroxy group, an optionally substituted amino group, SR5, an oxo group, a thioxo group, an optionally substituted imino group, a nitro group, a cyano group, etc., each m may be same or different and is 0 or 1, n is an integer of 1 to 3, q1 is an integer of 1 to 2n+4, q2 is an integer of 0 to 2n+3, and the sum of q1 and q2 is 2n+4 or a salt thereof.

摘要翻译： 本发明提供由下式表示的化合物：其中环A和环B可以相同或不同，并且各自为任选取代的杂环或杂环等，每个R 1可以相同或不同 并且是氢原子，任选取代的烃基，酰基，任选取代的杂环基或SR 2等，X 1是一个键，任选地 取代的二价C 1-3 - 脂族烃基或-NR 3 - 等，X 2是一个键，任选取代的二价C < -SO 3 - 脂族烃基，-NR 4 - ， - O-或-S（O）p - （其中p为0,1） 或2）中，每个Y可以相同或不同，为氢原子，任选取代的烃基，卤素原子，羧基，酰基，任选取代的羟基，任选取代的氨基，SR

公开(公告)号：US06699881B2

公开(公告)日：2004-03-02

申请号：US10161289

申请日：2002-06-03

申请人： Toshiro Yamashita ,  Hiroshi Nara ,  Masayuki Takizawa ,  Koji Yoshimura

发明人： Toshiro Yamashita ,  Hiroshi Nara ,  Masayuki Takizawa ,  Koji Yoshimura

IPC分类号： C07D21198

CPC分类号： C07D207/273 ,  C07D207/40 ,  C07D207/416 ,  C07D209/48 ,  C07D211/76 ,  C07D211/78 ,  C07D211/88 ,  C07D401/12 ,  C07D403/12 ,  C07D405/06 ,  C07D405/12 ,  C07D409/12

摘要： The present invention provides a compound represented by Formula: wherein ring A and ring B may be same or different and each is an optionally substituted homocyclic or heterocyclic ring and the like, each R1 may be same or different and is a hydrogen atom, an optionally substituted hydrocarbon group, an acyl group, an optionally substituted heterocyclic group or SR2, etc., X1 is a bond, an optionally substituted divalent C1-3 aliphatic hydrocarbon group or —NR3—, etc, X2 is a bond, an optionally substituted divalent C1-3 aliphatic hydrocarbon group, —NR4—, —O— or —S(O)p— (wherein p is 0, 1 or 2), each Y may be same or different and is a hydrogen atom, an optionally substituted hydrocarbon group, a halogen atom, a carboxyl group, an acyl group, an optionally substituted hydroxy group, an optionally substituted amino group, SR5, an oxo group, a thioxo group, an optionally substituted imino group, a nitro group, a cyano group, etc., each m may be same or different and is 0 or 1, n is an integer of 1 to 3, q1 is an integer of 1 to 2n+4, q2 is an integer of 0 to 2n+3, and the sum of q1 and q2 is 2n+4 or a salt thereof.

摘要翻译： 本发明提供由下式表示的化合物：其中环A和环B可以相同或不同，并且各自为任选取代的杂环或杂环等，各R 1可以相同或不同，为氢原子 ，任选取代的烃基，酰基，任选取代的杂环基或SR 2等，X 1是键，任选取代的二价C 1-3脂族烃基或-NR 3 - 等等，X 2是键，任选取代的二价C 1-3脂族烃基，-NR 4 - ， - O-或-S（O）p - （其中p是0,1或2） 每个Y可以相同或不同，为氢原子，任选取代的烃基，卤素原子，羧基，酰基，任选取代的羟基，任选取代的氨基，SR 5， 氧代基，硫代基，任选取代的亚氨基，硝基，氰基等，各m可以相同或不同，为0o r 1，n为1〜3的整数，q1为1〜2n + 4的整数，q2为0〜2n + 3的整数，q1和q2的和为2n +4或其盐。