Retriggerable multivibrator
    1.
    发明授权
    Retriggerable multivibrator 失效
    可再触发多谐振荡器

    公开(公告)号:US4994687A

    公开(公告)日:1991-02-19

    申请号:US277112

    申请日:1988-11-29

    IPC分类号: H03K3/02 H03K3/033

    CPC分类号: H03K3/033

    摘要: A retriggerable multivibrator is disclosed which comprises a first delay circuit connected for delaying an input signal a predetermined time, a second delay circuit connected to receive an output of the first delay circuit and having a enable or disable function, a flip-flop circuit connected to be set or reset in accordance with an input signal and output signal from the second delay circuit, and a control circuit for detecting a subsequent input signal within a predetermined delay time to enable or disable the second delay circuit.

    Voltage controlled oscillator
    3.
    发明授权
    Voltage controlled oscillator 失效
    压控振荡器

    公开(公告)号:US4859970A

    公开(公告)日:1989-08-22

    申请号:US277108

    申请日:1988-11-29

    CPC分类号: H03L7/081 H03L7/0891

    摘要: A voltage controlled oscillator comprises a phase locked loop section and a voltage controlled oscillator section. The phase locked loop section is coupled with an input signal at a reference frequency and a reference potential, and performs a signal feedback control so as to obtain a constant delay time of a first variable delay circuit contained in the phase locked loop section. The voltage controlled oscillator section controls a delay time of a second variable delay circuit in a ring oscillator by a control input voltage and an output voltage of a low-pass filter contained in the phase locked loop section, and produces a signal oscillating at a frequency as determined by the delay time. In the voltage controlled oscillator thus arranged, the output frequency is determined by controlling a delay time of the second variable delay circuit in the voltage controlled oscillator section. Since the delay time is accurately controlled by the phase locked loop section, the obtained output frequency is stable against the variance of the process parameters. Since the delay time is varied by the reference frequency of the input signal, the output frequency may be set at a desired frequency, and hence a frequency band of the oscillation frequencies may also be set appropriately.

    Indoline compound and process for producing the same
    4.
    发明授权
    Indoline compound and process for producing the same 有权
    二氢吲哚化合物及其制备方法

    公开(公告)号:US07834193B2

    公开(公告)日:2010-11-16

    申请号:US11787312

    申请日:2007-04-16

    IPC分类号: C07D209/12 C07D209/14

    CPC分类号: C07D209/08

    摘要: The present invention provides an industrial method production of silodosin, which is useful for a therapeutic agent for dysuria associated with benign prostatic hyperplasia. The production of silodosine is characterized by mixing 3-{7-cyano-5-[(2R)-2-({2-[2-(2,2,2-trifluoroethoxy)-phenoxy]ethyl}amino]propyl]-2,3-dihydro-1H-indol-1-yl}-propyl benzoate and oxalic acid to yield the oxalate, subsequently hydrolyzing the oxalate salt to yield 1-(3-hydroxypropyl)-5-[(2R)-2-({2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl}amino]propyl]-2,3-dihydro-1H-indole-7-carbonitrile and hydrolyzing the same, and manufacturing intermediates used therefore.

    摘要翻译: 本发明提供了可用于与良性前列腺增生相关的排尿困难的治疗剂的西洛德辛的工业方法生产。 酪氨酸的产生的特征在于将3- {7-氰基-5 - [(2R)-2 - ({2- [2-(2,2,2-三氟乙氧基) - 苯氧基]乙基}氨基]丙基] 2,3-二氢-1H-吲哚-1-基} - 丙基苯甲酸酯和草酸,得到草酸盐,随后水解草酸盐,得到1-(3-羟基丙基)-5 - [(2R)-2-( {2- [2-(2,2,2-三氟乙氧基)苯氧基]乙基}氨基]丙基] -2,3-二氢-1H-吲哚-7-甲腈并水解,由此制造中间体。

    Indoline compound and process for producting the same
    5.
    发明申请
    Indoline compound and process for producting the same 有权
    二氢吲哚化合物及其制备方法

    公开(公告)号:US20070197627A1

    公开(公告)日:2007-08-23

    申请号:US11787312

    申请日:2007-04-16

    IPC分类号: C07D209/14 A61K31/405

    CPC分类号: C07D209/08

    摘要: The present invention provides an industrial method production of silodosin, which is useful for a therapeutic agent for dysuria associated with benign prostatic hyperplasia. The production of silodosine is characterized by mixing 3-{7-cyano-5-[(2R)-2-({(2-[2-(2,2,2-trifluoroethoxy)-phenoxy]ethyl}amino]propyl]-2,3-dihydro-1H-indol-1-yl}-propyl benzoate and oxalic acid to yield the oxalate, subsequently hydrolyzing the oxalate salt to yield 1-(3-hydroxypropyl)-5-[(2R)-2-({2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl}amino]propyl]-2,3-dihydro-1H-indole-7-carbonitrile and hydrolyzing the same, and manufacturing intermediates used therefore.

    摘要翻译: 本发明提供了可用于与良性前列腺增生相关的排尿困难的治疗剂的西洛德辛的工业方法生产。 酪氨酸的产生的特征在于将3- {7-氰基-5 - [(2R)-2 - ({(2- [2-(2,2,2-三氟乙氧基) - 苯氧基]乙基}氨基]丙基] -2,3-二氢-1H-吲哚-1-基} - 丙基苯甲酸酯和草酸,得到草酸盐,随后水解草酸盐,得到1-(3-羟基丙基)-5 - [(2R)-2- ({2- [2-(2,2,2-三氟乙氧基)苯氧基]乙基}氨基]丙基] -2,3-二氢-1H-吲哚-7-甲腈并水解,由此制造中间体。