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11 条记录 (耗时 0.022 秒)

    Cephalosporins
    1.
    发明授权
    Cephalosporins 失效
    头孢菌素

    公开(公告)号：US4160830A

    公开(公告)日：1979-07-10

    申请号：US842153

    申请日：1977-10-14

    申请人： Shiro Morimoto ,  Hiroaki Nomura ,  Takeshi Fugono ,  Isao Minami

    发明人： Shiro Morimoto ,  Hiroaki Nomura ,  Takeshi Fugono ,  Isao Minami

    IPC分类号： A61K31/54

    CPC分类号： C07D501/38

    摘要： A method of combating bacterial infections in humans involves the administration of an antibacterially effective amount of a compound of the formula: ##STR1## wherein R is phenyl or thienyl group, and R' is a group which constitutes together with the adjacent nitrogen atom a pyridinium group that is unsubstituted or substituted by carbamoyl, or a 4'-methyl-5'-(.beta.-hydroxyethyl)-thiazolium or a pharmaceutically acceptable salt thereof, to a patient. This method is effective particularly against Pseudomonas aeruginosa as well as against other Gram negative and positive microorganisms.

    摘要翻译： 一种抗人类细菌感染的方法包括施用抗菌有效量的下式化合物：其中R是苯基或噻吩基，R'是与相邻氮原子一起构成的一个吡啶鎓 未取代或被氨基甲酰基取代的基团，或4'-甲基-5' - （β-羟乙基） - 噻唑鎓或其药学上可接受的盐。 该方法特别针对铜绿假单胞菌以及其他革兰氏阴性和阳性微生物有效。

    7-(.alpha.-Sulfoacylamido)cephalosporins
    2.
    发明授权
    7-(.alpha.-Sulfoacylamido)cephalosporins 失效
    7 - （{60-磺酰基氨基）头孢菌素

    公开(公告)号：US4065619A

    公开(公告)日：1977-12-27

    申请号：US719704

    申请日：1976-09-02

    申请人： Shiro Morimoto ,  Hiroaki Nomura ,  Takeshi Fugono ,  Isao Minami

    发明人： Shiro Morimoto ,  Hiroaki Nomura ,  Takeshi Fugono ,  Isao Minami

    IPC分类号： A61K31/545 ,  C07D501/38 ,  C07D501/44 ,  C07D501/46

    CPC分类号： C07D501/38

    摘要： Novel cephalosporins of the formula, ##STR1## wherein R is a hydrogen atom or an alkyl, aryl or thienyl group, and R' is a group which constitutes together with the adjacent nitrogen atom a 5- or 6-membered ring containing 1 or 2 nitrogen atoms, which are effective particularly against Pseudomonas aeruginosa as well as against other Gram negative and positive microorganisms, for example, N-[7-(.alpha.-sulfophenylacetamido)ceph-3-em-3-ylmethyl] pyridinium 4-carboxylate, N-[7-(.alpha.-sulfo-3'-thienylacetamido)ceph-3-em-3-ylmethyl] pyridinium-4-carboxylate, and their pharmaceutically acceptable salts thereof. Sodium salt of the former is prepared by, e.g. reacting sodium 7-(.alpha.-sulfophenylacetamido) cephalosporanate with pyridine in water.

    摘要翻译： 新颖的下式头孢菌素其中R是氢原子或烷基，芳基或噻吩基，R'是与相邻氮原子一起构成含有1或2的5-或6-元环的基团 氮原子，其特别对绿脓假单胞菌以及其他革兰氏阴性和阳性微生物有效，例如N- [7-（α-磺基苯基乙酰氨基）头孢-3-烯-3-基甲基]吡啶鎓4-羧酸盐，N - [7-（α-磺基-3'-噻吩基乙酰胺基）头孢-3-烯-3-基甲基]吡啶鎓-4-羧酸盐及其药学上可接受的盐。 前者的钠盐通过例如 使7-（α-磺基苯基乙酰氨基）头孢菌素钠与吡啶在水中反应。

    Method of producing 5-fluorouracil derivatives
    5.
    发明授权
    Method of producing 5-fluorouracil derivatives 失效
    生产5-氟尿嘧啶衍生物的方法

    公开(公告)号：US4249006A

    公开(公告)日：1981-02-03

    申请号：US744929

    申请日：1976-11-24

    申请人： Isao Minami ,  Yoshio Yoshioka ,  Hiroaki Nomura

    发明人： Isao Minami ,  Yoshio Yoshioka ,  Hiroaki Nomura

    IPC分类号： C07D405/14 ,  C07D405/04

    CPC分类号： C07D405/14

    摘要： A new and industrially useful method of producing 1(or 1,3-bis)-(tetrahydro-2-furyl)-5-fluorouracil or a mixture thereof by reacting 5-fluorouracil with 2,3-dihydrofuran at elevated temperature in a closed vessel. Depending upon reaction conditions, each of the above 5-fluorouracil derivatives or a mixture of them is produced.1,3-Bis-(tetrahydro-2-furyl)-5-fluorouracil thus formed can be converted to 1-(tetrahydro-2-furyl)-5-fluorouracil by solvolysis under non-acidic conditions.

    摘要翻译： 一种新的和工业上有用的方法，通过在高温下将5-氟尿嘧啶与2,3-二氢呋喃在封闭的环境中反应生产1（或1,3-双） - （四氢-2-呋喃基）-5-氟尿嘧啶或其混合物 船只。 根据反应条件，制备上述5-氟尿嘧啶衍生物或它们的混合物。 如此形成的1,3-双 - （四氢-2-呋喃基）-5-氟尿嘧啶可以在非酸性条件下通过溶剂分解转化成1-（四氢-2-呋喃基）-5-氟尿嘧啶。

    Glycosyl derivatives and use thereof
    6.
    发明授权
    Glycosyl derivatives and use thereof 失效
    糖基衍生物及其用途

    公开(公告)号：US5037969A

    公开(公告)日：1991-08-06

    申请号：US532179

    申请日：1990-06-04

    申请人： Isao Minami ,  Hayao Ueno ,  Masahiko Fujino

    发明人： Isao Minami ,  Hayao Ueno ,  Masahiko Fujino

    IPC分类号： C07H15/08 ,  C07K1/107 ,  C08G65/26 ,  C08G65/32 ,  C08G65/329

    CPC分类号： C07H15/08 ,  C07K1/1077 ,  C08G65/2606 ,  C08G65/32 ,  C08G65/329

    摘要： The invention provides a compound of the formula (I): R--O--CH.sub.2 CH.sub.2 O.sub.m CH.sub.2).sub.n --Z wherein R is a glycosyl group, m is an optional positive integer, n is an integer from 1 to 3 and Z is --CHO, --CH.sub.2 OH or --COOH.The compound of the formula (I'): R--O--CH.sub.2 CH.sub.2 O.sub.m CH.sub.2).sub.n --CHO wherein R, m and n are as defined above and the formula (I"'): R--OCH.sub.2 CH.sub.2 O.sub.m CH.sub.2).sub.n --COOH wherein R, m and n are as defined above is useful as a chemically modifying agent for protein.The compound of the formula (I"): R--O--CH.sub.2 CH.sub.2 O.sub.m CH.sub.2).sub.n --CH.sub.2 OH wherein R, m and n are as defined above is useful as a protein fractionating agent.

    摘要翻译： 本发明提供式（I）化合物：RO-CH2CH2OmCH2）nZ其中R为糖基，m为任选的正整数，n为1至3的整数，Z为-CHO，-CH 2 OH或-COOH 。 式（I'）化合物：RO-CH2CH2OmCH2）n-CHO其中R，m和n如上所定义，和式（I“'）：R-OCH 2 CH 2 OCH 2 OCH 2）n -COOH其中R，m和n 如上所定义，可用作蛋白质的化学改性剂。 式（I“）化合物：R-O-CH 2 CH 2 OCH 2 OCH 2）n -CH 2 OH其中R，m和n如上定义，可用作蛋白质分馏剂。

    Method of removing nicotine in smoking and a smoking filter to be used therefor
    7.
    发明授权
    Method of removing nicotine in smoking and a smoking filter to be used therefor 失效
    吸烟中除去尼古丁的方法和用于吸烟的吸烟过滤器

    公开(公告)号：US3943940A

    公开(公告)日：1976-03-16

    申请号：US506192

    申请日：1974-09-13

    申请人： Isao Minami

    发明人： Isao Minami

    IPC分类号： A24D3/06 ,  A24D3/16 ,  A24B15/02 ,  A24B15/027 ,  A24B15/04

    CPC分类号： A24D3/16 ,  A24D3/061

    摘要： This invention relates to a method of removing nicotine in smoking and a smoking filter to be used therefore. The method according to the present invention comprising the impregnation of smoking filter with an aqueous solution of potassium permanganate and chlorine just before smoking and thereby to change, by the smoking filter through which smoke passes, poisonous nicotine contained in the smoke produced from burning of tobacco into nutritious vitamin which is a factor of vitamin B complex.

    摘要翻译： 本发明涉及一种在吸烟中除去尼古丁的方法和一种吸烟过滤器。 根据本发明的方法包括在抽烟之前用高锰酸钾和氯的水溶液浸渍吸烟过滤器，从而通过烟雾通过的吸烟过滤器，由烟草燃烧产生的烟雾中含有的有毒尼古丁 成为维生素B复合物的营养维生素。

    FOOT STRAP FOR PICKING UP A GOLF BALL
    8.
    发明申请
    FOOT STRAP FOR PICKING UP A GOLF BALL 审中-公开
    用于拾取高​​尔夫球的脚链

    公开(公告)号：US20160184677A1

    公开(公告)日：2016-06-30

    申请号：US14583724

    申请日：2014-12-28

    申请人： Isao Minami

    发明人： Isao Minami

    IPC分类号： A63B57/00

    CPC分类号： A63B47/02 ,  A63B57/20 ,  A63B2209/10

    摘要： A foot strap is provided for use for picking up a golf ball from ground and placing it on a tee. The foot strap comprises a belt including a fastening unit for fastening two end portions of the belt, and a socket attached to the belt and having an inner surface configured to fit around part of the golf ball for receiving and holding the golf bait with support of a golf club.

    摘要翻译： 提供一个脚带，用于从地面拾起高尔夫球并将其放置在三通上。 脚带包括带，该带包括用于紧固带的两个端部的紧固单元和附接到带的插座，并且具有被配置成围绕高尔夫球的一部分配合的内表面，用于接收和保持高尔夫诱饵， 一个高尔夫俱乐部

    Automatic book binding machine for cut-sheets
    9.
    发明授权
    Automatic book binding machine for cut-sheets 失效
    自动装订机用于切纸

    公开(公告)号：US5601389A

    公开(公告)日：1997-02-11

    申请号：US391127

    申请日：1995-02-21

    申请人： Isao Minami

    发明人： Isao Minami

    IPC分类号： B42C19/02 ,  B65H37/02 ,  B42C13/00

    CPC分类号： B42C19/02 ,  B65H37/02 ,  B65H2511/512 ,  B65H2511/514

    摘要： An automatic book binding machine for cut-sheets includes a main body, a belt conveyor mounted on the main body and a feeder mounted on the main body and adapted to feed cut-sheets. A front cover of the cut-sheets has an identification mark for identifying one book from other books. A detection sensor is mounted on the belt conveyor for detecting one end of the cut-sheets. A nozzle mounted on the belt conveyor is controlled by the detection sensor to automatically apply a linear band of glue along one edge of the cut-sheets. A first mark sensor is mounted on the belt conveyor to sense a detectable mark on one of the cut-sheets and control the nozzle to stop applying glue to the cut-sheet. A second mark sensor is mounted on the belt conveyor to sense the detectable mark and control the nozzle to resume application of glue to the cut-sheet. A pressing plate is mounted on the main body for stacking up for storage the cut-sheets onto which the linear band of glue has been applied, aligning the sides of each cut-sheet, and pressing the glue-applied areas of the cut-sheets for each book from the top of the front cover in cooperation with the first and second mark sensors.

    摘要翻译： 一种用于切割片的自动书签装订机包括主体，安装在主体上的皮带传送器和安装在主体上并适于馈送切纸的进纸器。 切纸的前盖具有用于从其他书中识别一本书的识别标记。 检测传感器安装在带式输送机上，用于检测切纸的一端。 安装在带式输送机上的喷嘴由检测传感器控制，以沿切割片的一个边缘自动施加线性胶带。 第一标记传感器安装在带式输送机上以感测其中一个切割片上的可检测标记，并控制喷嘴以停止向切割片施加胶水。 第二标记传感器安装在带式输送机上以感测可检测标记并控制喷嘴以恢复对切割片施加胶水。 压板安装在主体上用于堆叠以存放已经施加有线性胶带的切割片，对准每个切割片的侧面，并且按压切割片的涂胶区域 与第一和第二标记传感器配合，从前盖顶部的每本书。