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公开(公告)号：US20200239429A1
公开(公告)日：2020-07-30
申请号：US16652274
申请日：2018-11-15
发明人： Jiawang ZHU , Zhiquan SONG , Dong LONG , Lichun WANG , Jingyi WANG
IPC分类号： C07D401/04 , C07D333/56 , C07D215/14 , C07D215/227 , C07D215/38 , C07D413/04 , C07D215/36 , A61P1/16
摘要： The invention relates to an aromatic compound, pharmaceutical composition comprising the same, and a method for preparing the compound and an intermediate thereof. The invention also relates to use of the compound for the manufacture of a medicament for the prevention or treatment of a PPAR-related disease.
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公开(公告)号：US20220220075A1
公开(公告)日：2022-07-14
申请号：US17593773
申请日：2020-05-21
发明人： Shidong YI , Tianming WANG , Zhuan WU , Long LI , Chengxi YANG , Zhiquan SONG , Dong LONG , Qiang TIAN , Hongmei SONG , Tongtong XUE , Jingyi WANG
IPC分类号： C07D215/227 , A61P1/16
摘要： The present application relates to a solid form of a compound of Formula (I), a method for preparing the solid form, a pharmaceutical composition comprising the solid form, and uses of the solid form in preparing a medicament for treating or preventing peroxisome proliferator-activated receptor (PPAR)-related diseases such as nonalcoholic fatty liver disease (NAFLD).
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公开(公告)号：US20200277277A1
公开(公告)日：2020-09-03
申请号：US16879204
申请日：2020-05-20
发明人： Jiawang ZHU , Zhiquan SONG , Dong LONG , Lichun WANG , Jingyi WANG
IPC分类号： C07D401/04 , C07D215/38 , C07D333/56 , A61P1/16 , C07D215/227 , C07D215/14 , C07D413/04 , C07D215/36
摘要： The invention relates to an aromatic compound, pharmaceutical composition comprising the same, and a method for preparing the compound and an intermediate thereof. The invention also relates to use of the compound for the manufacture of a medicament for the prevention or treatment of a PPAR-related disease.
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公开(公告)号：US20200087248A1
公开(公告)日：2020-03-19
申请号：US16489474
申请日：2018-04-19
发明人： Jiawang ZHU , Zhiquan SONG , Long YANG , Rui LI , Shuai ZHANG , Lin ZHOU , Mingliang ZHAO , Zujian TANG , Wei ZHONG , Hong ZENG , Hongmei SONG , Xin ZHOU , Yuting TANG , Xiao HU , Lichun WANG , Jingyi WANG
IPC分类号： C07C235/56 , C07C231/14 , C07D217/04 , C07D277/24 , C07D209/44 , C07D211/16 , C07D239/26 , C07D235/18 , C07D277/66 , C07C211/24 , C07D309/14 , C07D213/40 , C07D319/16
摘要： The present invention relates to a fluoroallylamine derivative and use thereof. In particular, the present invention relates to a compound as shown in Formula I, a prodrug, an isomer, an isotope-labeled compound, a solvate or a pharmaceutically acceptable salt thereof, which has VAP-1/SSAO inhibitory activity, and can be used for treating a disease associated with VAP-1/SSAO overactivity.
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