公开(公告)号：US12031890B2

公开(公告)日：2024-07-09

申请号：US18007058

申请日：2021-07-23

申请人： Siemens Healthcare Diagnostics Inc.

发明人： Jeffrey R. Jasperse ,  Peter Paulicka ,  Paul Benson

IPC分类号： G01N1/28 ,  B01L3/00 ,  G01N29/036 ,  G01N29/34

CPC分类号： G01N1/286 ,  B01L3/502715 ,  G01N29/036 ,  G01N29/348 ,  B01L2300/0627 ,  B01L2300/0861 ,  B01L2300/12 ,  B01L2400/0436

摘要： A lysis device including a sample vessel, at least one piezo element, and a controller is disclosed. The sample vessel has a microchannel formed therein. The sample vessel has at least one port extending through a surface to the microchannel. The piezo element is attached to the surface of the sample vessel. The controller has logic to cause the controller to emit a first signal including a series of frequencies to the at least one piezo element to cause the at least one piezo element to generate ultrasonic acoustic standing waves in the sample vessel, to receive a second signal indicative of measured vibration signals from the sample vessel detected by the at least one piezo element, and to determine a resonant frequency of the sample vessel using the measured vibration signals.

公开(公告)号：US20240361211A1

公开(公告)日：2024-10-31

申请号：US18738633

申请日：2024-06-10

申请人： Siemens Healthcare Diagnostics Inc.

发明人： Jeffrey R. Jasperse ,  Peter Paulicka ,  Paul Benson

IPC分类号： G01N1/28 ,  B01L3/00 ,  G01N29/036 ,  G01N29/34

CPC分类号： G01N1/286 ,  B01L3/502715 ,  G01N29/036 ,  G01N29/348 ,  B01L2300/0627 ,  B01L2300/0861 ,  B01L2300/12 ,  B01L2400/0436

摘要： A lysis device including a sample vessel, at least one piezo element, and a controller is disclosed. The sample vessel has a microchannel formed therein. The sample vessel has at least one port extending through a surface to the microchannel. The piezo element is attached to the surface of the sample vessel. The controller has logic to cause the controller to emit a first signal including a series of frequencies to the at least one piezo element to cause the at least one piezo element to generate ultrasonic acoustic standing waves in the sample vessel, to receive a second signal indicative of measured vibration signals from the sample vessel detected by the at least one piezo element, and to determine a resonant frequency of the sample vessel using the measured vibration signals.

公开(公告)号：US20230213414A1

公开(公告)日：2023-07-06

申请号：US18007058

申请日：2021-07-23

申请人： Siemens Healthcare Diagnostics Inc.

发明人： Jeffrey R. Jasperse ,  Peter Paulicka ,  Paul Benson

IPC分类号： G01N1/28 ,  B01L3/00 ,  G01N29/34 ,  G01N29/036

CPC分类号： G01N1/286 ,  B01L3/502715 ,  G01N29/348 ,  G01N29/036 ,  B01L2300/0627 ,  B01L2300/0861 ,  B01L2400/0436 ,  B01L2300/12

摘要： A lysis device including a sample vessel, at least one piezo element, and a controller is disclosed. The sample vessel has a microchannel formed therein. The sample vessel has at least one port extending through a surface to the microchannel. The piezo element is attached to the surface of the sample vessel. The controller has logic to cause the controller to emit a first signal including a series of frequencies to the at least one piezo element to cause the at least one piezo element to generate ultrasonic acoustic standing waves in the sample vessel, to receive a second signal indicative of measured vibration signals from the sample vessel detected by the at least one piezo element, and to determine a resonant frequency of the sample vessel using the measured vibration signals.