公开(公告)号：US20240385172A1

公开(公告)日：2024-11-21

申请号：US18677117

申请日：2024-05-29

Applicant: Specific Technologies, LLC

Inventor： Paul A. Rhodes ,  Soumitesh Chakravorty ,  Sung Hyun Lim

IPC: G01N33/50 ,  C12Q1/02 ,  C12Q1/04 ,  C12Q1/18 ,  C12Q3/00 ,  G01N21/01 ,  G01N21/03 ,  G01N21/78 ,  G01N21/80

Abstract: Devices, systems, and methods for strain-specific identification and assessment of susceptibility of microorganisms based on the response of sensors in a colorimetric sensor array to metabolic products of the microorganism. An exemplary method includes culturing a sample containing microorganisms in a medium and in gaseous communication with a colorimetric sensor array. Sensors in the colorimetric sensor array are exposed to volatile organic compounds produced by the microorganism. The method then includes assessing a resistance of the microorganism to at least one substance. The resistance is assessed based on a response of the sensors in the colorimetric sensor array to the volatile organic compounds produced by the microorganism.

公开(公告)号：US20180252701A1

公开(公告)日：2018-09-06

申请号：US15907695

申请日：2018-02-28

Applicant: Specific Technologies, LLC

Inventor： Paul A. Rhodes ,  Soumitesh Chakravorty ,  Sung Hyun Lim

IPC: G01N33/50 ,  G01N21/03 ,  C12Q1/02 ,  C12Q3/00

CPC classification number: G01N33/5008 ,  C12Q1/025 ,  C12Q1/04 ,  C12Q1/18 ,  C12Q3/00 ,  G01N21/03 ,  G01N21/78 ,  G01N21/80 ,  G01N2021/0118 ,  G01N2201/0446

Abstract: Devices, systems, and methods for strain-specific identification and assessment of susceptibility of microorganisms based on the response of sensors in a colorimetric sensor array to metabolic products of the microorganism. An exemplary method includes culturing a sample containing microorganisms in a medium and in gaseous communication with a colorimetric sensor array. Sensors in the colorimetric sensor array are exposed to volatile organic compounds produced by the microorganism. The method then includes assessing a resistance of the microorganism to at least one substance. The resistance is assessed based on a response of the sensors in the colorimetric sensor array to the volatile organic compounds produced by the microorganism.

公开(公告)号：US12038429B2

公开(公告)日：2024-07-16

申请号：US15907695

申请日：2018-02-28

Applicant: Specific Technologies, LLC

Inventor： Paul A. Rhodes ,  Soumitesh Chakravorty ,  Sung Hyun Lim

IPC: G01N33/50 ,  C12Q1/02 ,  C12Q1/04 ,  C12Q1/18 ,  C12Q3/00 ,  G01N21/03 ,  G01N21/78 ,  G01N21/01 ,  G01N21/80

CPC classification number: G01N33/5008 ,  C12Q1/025 ,  C12Q1/04 ,  C12Q1/18 ,  C12Q3/00 ,  G01N21/03 ,  G01N21/78 ,  G01N2021/0118 ,  G01N21/80 ,  G01N2201/0446

Abstract: Devices, systems, and methods for strain-specific identification and assessment of susceptibility of microorganisms based on the response of sensors in a colorimetric sensor array to metabolic products of the microorganism. An exemplary method includes culturing a sample containing microorganisms in a medium and in gaseous communication with a colorimetric sensor array. Sensors in the colorimetric sensor array are exposed to volatile organic compounds produced by the microorganism. The method then includes assessing a resistance of the microorganism to at least one substance. The resistance is assessed based on a response of the sensors in the colorimetric sensor array to the volatile organic compounds produced by the microorganism.