公开(公告)号：US20190078123A1

公开(公告)日：2019-03-14

申请号：US16185924

申请日：2018-11-09

Applicant: Stepan Company

Inventor： Vladimir Dragan

IPC: C12P7/64

Abstract: An enzymatic process for producing fatty acid triglycerides using a lipase catalyst system that includes a mixture of a supported lipase catalyst and an additive, such as silica gel. The additive is used without adsorbing any of the acyl group donor or acyl group acceptor reactants onto the additive. Use of the catalyst system decreases production reaction time, decreases the temperatures required for reaction, and allows for a single reaction vessel. The catalyst system can be used to efficiently produce medium chain triglycerides or conjugated linoleic acid triglycerides.

公开(公告)号：US11008595B2

公开(公告)日：2021-05-18

申请号：US16185924

申请日：2018-11-09

Applicant: Stepan Company

Inventor： Vladimir Dragan

IPC: C12P7/64 ,  C07B41/12 ,  C12N11/02

Abstract: An enzymatic process for producing fatty acid triglycerides using a lipase catalyst system that includes a mixture of a supported lipase catalyst and an additive, such as silica gel. The additive is used without adsorbing any of the acyl group donor or acyl group acceptor reactants onto the additive. Use of the catalyst system decreases production reaction time, decreases the temperatures required for reaction, and allows for a single reaction vessel. The catalyst system can be used to efficiently produce medium chain triglycerides or conjugated linoleic acid triglycerides.

公开(公告)号：US20170152534A1

公开(公告)日：2017-06-01

申请号：US15428339

申请日：2017-02-09

Applicant: Stepan Company

Inventor： Vladimir Dragan ,  Jenifer Heydinger Galante ,  Jos Heimerikx

IPC: C12P7/64 ,  A23L33/12 ,  A61K31/201

CPC classification number: C12P7/6427 ,  A23K20/158 ,  A23L33/12 ,  A23V2002/00 ,  A61K31/201 ,  C11C1/045 ,  C11C1/10 ,  A23V2200/304 ,  A23V2200/328 ,  A23V2200/332 ,  A23V2250/1866

Abstract: A process for preparing a conjugated linoleic acid (CLA) material that is enriched in the cis 9, trans 11 (rumenic acid) CLA isomer. The process involves subjecting a material containing at least 75 weight % CLA moieties to an enzymatic conversion, wherein the enzyme has the ability to discriminate between the cis 9, trans 11 and trans 10, cis 12 isomers. The enzyme is advantageously a lipase derived from Candida rugosa. The resulting CLA product stream is distilled to separate the free fatty acid fraction from the glyceride fraction. The recovered free fatty acid fraction contains about 55 weight % to about 70 weight % of the cis 9, trans 11 isomer (rumenic acid), and has a weight ratio of cis 9, trans 11 isomer to trans 10, cis 12 isomer of at least 3.5:1. The material enriched in rumenic acid may be used in foods, particularly infant formulas, or in food supplements or in pharmaceutical compositions.