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公开(公告)号：US20090288337A1
公开(公告)日：2009-11-26
申请号：US12332305
申请日：2008-12-10
申请人： Stephen Picataggio , Robert Christopher Brown , Jessica Roxane Kristof , Gena Lee , Prachee Prakash , Stuart Alan Underwood , Kevin Watts
发明人： Stephen Picataggio , Robert Christopher Brown , Jessica Roxane Kristof , Gena Lee , Prachee Prakash , Stuart Alan Underwood , Kevin Watts
IPC分类号： C10L1/185 , C12N1/19 , C12P7/16 , C12P7/00 , C12P5/02 , C07C31/125 , C07C43/04 , C10L1/18 , C10L1/182
CPC分类号： C12P7/16 , C10L1/02 , C12N9/0006 , C12N9/0008 , C12N9/1022 , C12N9/1096 , C12N9/1205 , C12N9/1217 , C12N9/88 , C12N9/93 , C12P7/04 , Y02E50/343
摘要： This invention describes genes, metabolic pathways, microbial strains and methods to produce methyl butanol and other compounds of interest from renewable feedstocks.
摘要翻译： 本发明描述了可再生原料生产甲基丁醇和其他化合物的基因，代谢途径，微生物菌株和方法。
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公开(公告)号：US09080188B2
公开(公告)日：2015-07-14
申请号：US13305414
申请日：2011-11-28
申请人： Stephen Picataggio , Robert C. Brown , Jessica R. Kristof , Gena Roy , Prachee Prakash , Stuart A. Underwood , Kevin Watts , Kevin V. Martin
发明人： Stephen Picataggio , Robert C. Brown , Jessica R. Kristof , Gena Roy , Prachee Prakash , Stuart A. Underwood , Kevin Watts , Kevin V. Martin
IPC分类号： C12N1/00 , C12P7/00 , C12P7/64 , C12P7/16 , C12N9/00 , C12N9/02 , C12P21/06 , C07H21/04 , C10L1/02 , C12N9/04 , C12N9/10 , C12N9/12 , C12N9/88 , C12P7/04
CPC分类号： C12P7/16 , C10L1/02 , C12N9/0006 , C12N9/0008 , C12N9/1022 , C12N9/1096 , C12N9/1205 , C12N9/1217 , C12N9/88 , C12N9/93 , C12P7/04 , Y02E50/343
摘要： This invention describes genes, metabolic pathways, microbial strains and methods to produce methylbutanol and other compounds of interest from renewable feedstocks.
摘要翻译： 本发明描述了可再生原料生产甲基丁醇和其他化合物的基因，代谢途径，微生物菌株和方法。
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公开(公告)号：US20140322780A1
公开(公告)日：2014-10-30
申请号：US13305414
申请日：2011-11-28
申请人： Stephen Picataggio , Robert C. Brown , Jessica R. Kristof , Gena Roy , Prachee Prakash , Stuart A. Underwood , Kevin Watts , Kevin V. Martin
发明人： Stephen Picataggio , Robert C. Brown , Jessica R. Kristof , Gena Roy , Prachee Prakash , Stuart A. Underwood , Kevin Watts , Kevin V. Martin
CPC分类号： C12P7/16 , C10L1/02 , C12N9/0006 , C12N9/0008 , C12N9/1022 , C12N9/1096 , C12N9/1205 , C12N9/1217 , C12N9/88 , C12N9/93 , C12P7/04 , Y02E50/343
摘要： This invention describes genes, metabolic pathways, microbial strains and methods to produce methylbutanol and other compounds of interest from renewable feedstocks.
摘要翻译： 本发明描述了可再生原料生产甲基丁醇和其他化合物的基因，代谢途径，微生物菌株和方法。
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公开(公告)号：US08114641B2
公开(公告)日：2012-02-14
申请号：US12332305
申请日：2008-12-10
申请人： Stephen Picataggio , Robert C. Brown , Jessica R. Kristof , Gena Roy , Prachee Prakash , Stuart A. Underwood , Kevin Watts , Kevin V. Martin
发明人： Stephen Picataggio , Robert C. Brown , Jessica R. Kristof , Gena Roy , Prachee Prakash , Stuart A. Underwood , Kevin Watts , Kevin V. Martin
IPC分类号： C12P7/00 , C12P7/16 , C12P5/02 , C12P21/06 , C12N9/02 , C12N9/00 , C12N1/16 , C10L1/18 , C07H21/04
CPC分类号： C12P7/16 , C10L1/02 , C12N9/0006 , C12N9/0008 , C12N9/1022 , C12N9/1096 , C12N9/1205 , C12N9/1217 , C12N9/88 , C12N9/93 , C12P7/04 , Y02E50/343
摘要： This invention describes genes, metabolic pathways, microbial strains and methods to produce methyl butanol and other compounds of interest from renewable feedstocks.
摘要翻译： 本发明描述了可再生原料生产甲基丁醇和其他化合物的基因，代谢途径，微生物菌株和方法。
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5.发明申请CELL SYSTEMS AND METHODS FOR IMPROVING FATTY ACID SYNTHESIS BY EXPRESSION OF DEHYDROGENASES 有权通过表达脱氢酶改善脂肪酸合成的细胞系统和方法公开(公告)号：US20130280793A1
公开(公告)日：2013-10-24
申请号：US13453235
申请日：2012-04-23
申请人： Robert Christopher Brown , Jennifer Coppersmith , Prachee Prakash , Srividya Akella , Rekha Seshadri
发明人： Robert Christopher Brown , Jennifer Coppersmith , Prachee Prakash , Srividya Akella , Rekha Seshadri
CPC分类号： C12P7/64 , C12N9/0006 , C12Y101/01044 , C12Y101/99006 , C12Y102/01
摘要： The invention relates to methods for producing lipids such as fatty acid products in recombinant host cells engineered to express a non-native gene encoding a dehydrogenase. The recombinant microorganisms are able to proliferate at a higher rate as compared with microorganisms that do not express a non-native dehydrogenase gene, and cultures of microorganisms that are engineered for lipid production and that express a non-native dehydrogenase produce more lipid than cultures of control microorganisms that do not include a non-native dehydrogenase gene.
摘要翻译： 本发明涉及在重组宿主细胞中生产脂质如脂肪酸产物的方法，其工程化以表达编码脱氢酶的非天然基因。 与不表达非天然脱氢酶基因的微生物相比，重组微生物能够以更高的速率增殖，并且为脂质生产而工程改造并且表达非天然脱氢酶的微生物培养物产生比含有 控制不包括非天然脱氢酶基因的微生物。
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6.发明授权Cell systems and methods for improving fatty acid synthesis by expression of dehydrogenases 有权用于通过脱氢酶表达改善脂肪酸合成的细胞系统和方法公开(公告)号：US09181568B2
公开(公告)日：2015-11-10
申请号：US13453235
申请日：2012-04-23
申请人： Robert Christopher Brown , Jennifer Coppersmith , Prachee Prakash , Srividya Akella , Rekha Seshadri
发明人： Robert Christopher Brown , Jennifer Coppersmith , Prachee Prakash , Srividya Akella , Rekha Seshadri
CPC分类号： C12P7/64 , C12N9/0006 , C12Y101/01044 , C12Y101/99006 , C12Y102/01
摘要： The invention relates to methods for producing lipids such as fatty acid products in recombinant host cells engineered to express a non-native gene encoding a dehydrogenase. The recombinant microorganisms are able to proliferate at a higher rate as compared with microorganisms that do not express a non-native dehydrogenase gene, and cultures of microorganisms that are engineered for lipid production and that express a non-native dehydrogenase produce more lipid than cultures of control microorganisms that do not include a non-native dehydrogenase gene.
摘要翻译： 本发明涉及在重组宿主细胞中生产脂质如脂肪酸产物的方法，其工程化以表达编码脱氢酶的非天然基因。 与不表达非天然脱氢酶基因的微生物相比，重组微生物能够以更高的速率增殖，并且为脂质生产而工程改造并且表达非天然脱氢酶的微生物培养物产生比含有 控制不包括非天然脱氢酶基因的微生物。
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