公开(公告)号：US07288089B2

公开(公告)日：2007-10-30

申请号：US11151488

申请日：2005-06-13

申请人： Steven A. Yon ,  John D. Dobak, III ,  Hans W. Kramer ,  Rebecca S. Inderbitzen

发明人： Steven A. Yon ,  John D. Dobak, III ,  Hans W. Kramer ,  Rebecca S. Inderbitzen

IPC分类号： A61B18/18

CPC分类号： A61F7/12 ,  A61B18/02 ,  A61B18/08 ,  A61B2017/00243 ,  A61B2017/22002 ,  A61B2017/22051 ,  A61B2017/22054 ,  A61B2018/00023 ,  A61B2018/00041 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61F2007/126

摘要： An enhanced method and device are provided to treat atrial fibrillation or inhibit or reduce restenosis following angioplasty or stent placement. A balloon-tipped catheter is disposed in the area treated or opened through balloon angioplasty immediately following angioplasty. The balloon, which can have a dual balloon structure, may be delivered through a guiding catheter and over a guidewire already in place. A fluid such as a perfluorocarbon flows into the balloon to freeze the tissue adjacent the balloon, this cooling being associated with reduction of restenosis. A similar catheter may be used to reduce atrial fibrillation by inserting and inflating the balloon such that an exterior surface of the balloon contacts at least a partial circumference of the portion of the pulmonary vein adjacent the left atrium. In another embodiment, blood perfusion is performed simultaneously. In another embodiment, tissue contacted by the cryoablation catheter, undesired to be ablated, is protected against damage by a separate heating step.

摘要翻译： 提供增强的方法和装置以治疗房颤或抑制或减少血管成形术或支架置入后的再狭窄。 血管成形术后立即将球囊导管放置在通过球囊血管成形术处理或打开的区域中。 可以具有双气囊结构的气囊可以通过引导导管并且已经在已经就位的导丝上传送。 诸如全氟化碳的流体流入气球以冷冻邻近球囊的组织，这种冷却与再狭窄的减少有关。 类似的导管可用于通过插入和充气气囊来减少心房颤动，使得球囊的外表面接触邻近左心房的肺静脉部分的至少部分圆周。 在另一个实施方案中，同时进行血液灌注。 在另一个实施方案中，由冷冻消融导管接触的不希望消融的组织通过单独的加热步骤被保护而不被损坏。

公开(公告)号：US08043351B2

公开(公告)日：2011-10-25

申请号：US11978787

申请日：2007-10-30

申请人： Steven A. Yon ,  John D. Dobak, III ,  Hans W. Kramer ,  Rebecca S. Inderbitzen

发明人： Steven A. Yon ,  John D. Dobak, III ,  Hans W. Kramer ,  Rebecca S. Inderbitzen

IPC分类号： A61F7/12

CPC分类号： A61F7/12 ,  A61B18/02 ,  A61B18/08 ,  A61B2017/00243 ,  A61B2017/22002 ,  A61B2017/22051 ,  A61B2017/22054 ,  A61B2018/00023 ,  A61B2018/00041 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61F2007/126

摘要： An enhanced method and device are provided to treat atrial fibrillation or inhibit or reduce restenosis following angioplasty or stent placement. A balloon-tipped catheter is disposed in the area treated or opened through balloon angioplasty immediately following angioplasty. The balloon, which can have a dual balloon structure, may be delivered through a guiding catheter and over a guidewire already in place. A fluid such as a perfluorocarbon flows into the balloon to freeze the tissue adjacent the balloon, this cooling being associated with reduction of restenosis. A similar catheter may be used to reduce atrial fibrillation by inserting and inflating the balloon such that an exterior surface of the balloon contacts at least a partial circumference of the portion of the pulmonary vein adjacent the left atrium. In another embodiment, blood perfusion is performed simultaneously. In another embodiment, tissue contacted by the cryoablation catheter, undesired to be ablated, is protected against damage by a separate heating step.

摘要翻译： 提供增强的方法和装置以治疗房颤或抑制或减少血管成形术或支架置入后的再狭窄。 血管成形术后立即将球囊导管放置在通过球囊血管成形术处理或打开的区域中。 可以具有双气囊结构的气囊可以通过引导导管并且已经在已经就位的导丝上传送。 诸如全氟化碳的流体流入气球以冷冻邻近球囊的组织，这种冷却与再狭窄的减少有关。 类似的导管可用于通过插入和充气气囊来减少心房颤动，使得球囊的外表面接触邻近左心房的肺静脉部分的至少部分圆周。 在另一个实施方案中，同时进行血液灌注。 在另一个实施方案中，由冷冻消融导管接触的不希望消融的组织通过单独的加热步骤被保护而不被损坏。

公开(公告)号：US07001378B2

公开(公告)日：2006-02-21

申请号：US10110360

申请日：2002-03-01

申请人： Steven A. Yon ,  John D. Dobak, III ,  Hans W. Kramer ,  Stephen R. Cooper ,  Rebecca S. Inderbitzen

发明人： Steven A. Yon ,  John D. Dobak, III ,  Hans W. Kramer ,  Stephen R. Cooper ,  Rebecca S. Inderbitzen

IPC分类号： A61B18/18

CPC分类号： A61F7/12 ,  A61B18/02 ,  A61B18/08 ,  A61B2017/22002 ,  A61B2017/22051 ,  A61B2017/22054 ,  A61B2018/00023 ,  A61B2018/00041 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61F2007/126

摘要： An enhanced method and device are provided to treat atrial fibrillation or inhibit or reduce restenosis following angioplasty or stent placement. A balloon-tipped catheter is disposed in the area treated or opened through balloon angioplasty immediately following angioplasty. The balloon, which can have a dual balloon structure, may be delivered through a guiding catheter and over a guidewire already in place. A fluid such as a perfluorocarbon flows into the balloon to freeze the tissue adjacent the balloon, this cooling being associated with reduction of restenosis. A similar catheter may be used to reduce atrial fibrillation by inserting and inflating the balloon such that an exterior surface of the balloon contacts at least a partial circumference of the portion of the pulmonary vein adjacent the left atrium. In another embodiment, blood perfusion is performed simultaneously. In another embodiment, tissue contacted by the cryoablation catheter, undesired to be ablated, is protected against damage by a separate heating step.

公开(公告)号：US06905494B2

公开(公告)日：2005-06-14

申请号：US10086585

申请日：2002-02-28

申请人： Steven A. Yon ,  John D. Dobak, III ,  Hans W. Kramer ,  Rebecca S. Inderbitzen

发明人： Steven A. Yon ,  John D. Dobak, III ,  Hans W. Kramer ,  Rebecca S. Inderbitzen

IPC分类号： A61B17/00 ,  A61B17/22 ,  A61B18/00 ,  A61B18/02 ,  A61B18/08 ,  A61F7/12 ,  A61B18/18

CPC分类号： A61F7/12 ,  A61B18/02 ,  A61B18/08 ,  A61B2017/00243 ,  A61B2017/22002 ,  A61B2017/22051 ,  A61B2017/22054 ,  A61B2018/00023 ,  A61B2018/00041 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61F2007/126

摘要： An enhanced method and device are provided to treat atrial fibrillation or inhibit or reduce restenosis following angioplasty or stent placement. A balloon-tipped catheter is disposed in the area treated or opened through balloon angioplasty immediately following angioplasty. The balloon, which can have a dual balloon structure, may be delivered through a guiding catheter and over a guidewire already in place. A fluid such as a perfluorocarbon flows into the balloon to freeze the tissue adjacent the balloon, this cooling being associated with reduction of restenosis. A similar catheter may be used to reduce atrial fibrillation by inserting and inflating the balloon such that an exterior surface of the balloon contacts at least a partial circumference of the portion of the pulmonary vein adjacent the left atrium. In another embodiment, blood perfusion is performed simultaneously. In another embodiment, tissue contacted by the cryoablation catheter, undesired to be ablated, is protected against damage by a separate heating step.

摘要翻译： 提供增强的方法和装置以治疗房颤或抑制或减少血管成形术或支架置入后的再狭窄。 血管成形术后立即将球囊导管放置在通过球囊血管成形术处理或打开的区域中。 可以具有双气囊结构的气囊可以通过引导导管并且已经在已经就位的导丝上传送。 诸如全氟化碳的流体流入气球以冷冻邻近球囊的组织，这种冷却与再狭窄的减少有关。 类似的导管可用于通过插入和充气气囊来减少心房颤动，使得球囊的外表面接触邻近左心房的肺静脉部分的至少部分圆周。 在另一个实施方案中，同时进行血液灌注。 在另一个实施方案中，由冷冻消融导管接触的不希望消融的组织通过单独的加热步骤被保护而不被损坏。

公开(公告)号：US08663236B2

公开(公告)日：2014-03-04

申请号：US11238279

申请日：2005-09-28

申请人： Eugene G. Chen ,  Vahid C. Saadat ,  Rebecca S. Inderbitzen ,  Lee L. Swanstrom

发明人： Eugene G. Chen ,  Vahid C. Saadat ,  Rebecca S. Inderbitzen ,  Lee L. Swanstrom

IPC分类号： A61F11/00

CPC分类号： A61B17/0057 ,  A61B17/0401 ,  A61B17/0487 ,  A61B17/320016 ,  A61B17/3415 ,  A61B17/3421 ,  A61B17/3478 ,  A61B2017/00278 ,  A61B2017/00637 ,  A61B2017/00663 ,  A61B2017/0419 ,  A61B2017/0445 ,  A61B2017/0454 ,  A61B2017/0464 ,  A61B2017/0496 ,  A61B2017/22044 ,  A61B2017/3445 ,  A61B2017/3488

摘要： Transgastric abdominal access methods and apparatus are described herein. A shape-lockable elongate body can be advanced endoluminally in a flexible state into the stomach, where an opening is created through the stomach wall. The opening can be created endoluminally or by incising instruments placed through the abdominal wall. The elongate body can be transitioned to a rigid state prior to, during, or after advancement into the patient and is passed through the opening into the peritoneal cavity. A dilation balloon can be positioned simultaneously within the elongate body and within the tissue opening such that the elongate body can be advanced through the tissue opening. A flexible needle catheter can also be delivered through the elongate body or an endoscope to provide for insufflation prior to cutting or piercing through the stomach wall. Also, tissue closure devices and methods to close the opening created through the stomach wall.

摘要翻译： 腹部腹部进入方法和装置在本文中描述。 形状可锁定的细长体可以以柔性状态进入胃内，其中通过胃壁产生开口。 可以通过腹腔内或通过切开通过腹壁放置的器械来创建开口。 细长体可以在进入患者之前，期间或之后转变到刚性状态，并且通过开口进入腹膜腔。 扩张气囊可以同时地定位在细长主体内和组织开口内，使得细长主体能够穿过组织开口。 柔性针导管还可以通过细长体或内窥镜输送，以在切割或刺穿胃壁之前提供吹气。 此外，组织闭合装置和闭合通过胃壁产生的开口的方法。