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公开(公告)号:US07708993B2
公开(公告)日:2010-05-04
申请号:US11359254
申请日:2006-02-21
IPC分类号: A61K39/395
CPC分类号: C07K14/47 , C07K14/705 , C07K16/2818 , C07K16/2827 , C07K2317/73 , C07K2319/30
摘要: Polypeptides which comprise a receptor-ligand pair involved in T-cell activation are disclosed. Nucleic acid molecules encoding the polypeptides, and vectors and host cells for expressing the polypeptides are also disclosed. The polypeptides, or agonists and antagonists thereof, are used to treat T-cell mediated disorders.
摘要翻译: 公开了包含参与T细胞活化的受体 - 配体对的多肽。 还公开了编码多肽的核酸分子,以及用于表达多肽的载体和宿主细胞。 多肽或其激动剂和拮抗剂用于治疗T细胞介导的病症。
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公开(公告)号:US08309083B2
公开(公告)日:2012-11-13
申请号:US12753819
申请日:2010-04-02
IPC分类号: A61K39/395
CPC分类号: C07K14/47 , C07K14/705 , C07K16/2818 , C07K16/2827 , C07K2317/73 , C07K2319/30
摘要: Polypeptides which comprise a receptor-ligand pair involved in T-cell activation are disclosed. Nucleic acid molecules encoding the polypeptides, and vectors and host cells for expressing the polypeptides are also disclosed. The polypeptides, or agonists and antagonists thereof, are used to treat T-cell mediated disorders.
摘要翻译: 公开了包含参与T细胞活化的受体 - 配体对的多肽。 还公开了编码多肽的核酸分子,以及用于表达多肽的载体和宿主细胞。 多肽或其激动剂和拮抗剂用于治疗T细胞介导的病症。
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公开(公告)号:US20060140944A1
公开(公告)日:2006-06-29
申请号:US11359254
申请日:2006-02-21
申请人: Steven Yoshinaga , Tak Mak , Arda Shahinian , Anna Bladt , Giorgio Senaldi
发明人: Steven Yoshinaga , Tak Mak , Arda Shahinian , Anna Bladt , Giorgio Senaldi
IPC分类号: A61K39/395 , C12Q1/68 , G01N33/567 , C07H21/04 , C12P21/04 , C07K14/705 , C07K16/28
CPC分类号: C07K14/47 , C07K14/705 , C07K16/2818 , C07K16/2827 , C07K2317/73 , C07K2319/30
摘要: Novel polypeptides which comprise a receptor-ligand pair involved in T-cell activation are disclosed. Nucleic acid molecules encoding said polypeptides, and vectors and host cells for expressing same are also disclosed. The polypeptides, or agonists and antagonists thereof, are used to treat T-cell mediated disorders.
摘要翻译: 公开了包含参与T细胞活化的受体 - 配体对的新型多肽。 还公开了编码所述多肽的核酸分子,以及用于表达其的载体和宿主细胞。 多肽或其激动剂和拮抗剂用于治疗T细胞介导的病症。
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