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1.发明授权
公开(公告)号：US5478924A
公开(公告)日：1995-12-26
申请号：US197146
申请日：1994-02-16
申请人： Steven M. Cramer , James A. Moore , Amitava Kundu , Yufei Li , Guhan Jayaraman
发明人： Steven M. Cramer , James A. Moore , Amitava Kundu , Yufei Li , Guhan Jayaraman
IPC分类号： C07C217/08 , B01D15/42 , C07C215/40 , C07K1/18 , G01N30/02 , C07K1/14 , C07C211/62 , C07K1/16
CPC分类号： B01D15/422 , C07C215/40 , C07K1/18 , G01N30/02
摘要： A method for the purification of proteins by displacement chromatography on ion exchange media using low molecular weight displacers is disclosed. Several classes of low molecular weight, charged species are exemplified, including aminoacids, peptides, antibiotics and dendrimeric polymers. Novel compounds useful as displacers are dendrimers of formula ##STR1## wherein R.sup.1 is lower alkyl, n is 2 to 6, and X is a common counter anion and similar dendritic polymers based thereon.
摘要翻译： 公开了一种使用低分子量置换器在离子交换介质上通过置换色谱法纯化蛋白质的方法。 例举了几类低分子量带电物质，包括氨基酸，肽，抗生素和树枝状聚合物。 可用作置换剂的新型化合物是式“IMAGE”的树枝状大分子，其中R 1是低级烷基，n是2-6，X是常见的抗衡阴离子和类似的树枝状聚合物。
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2.发明授权Displacement chromatography of proteins using low molecular weight anionic displacers 失效使用低分子量阴离子置换剂的蛋白质置换色谱法
公开(公告)号：US5606033A
公开(公告)日：1997-02-25
申请号：US545457
申请日：1995-10-19
申请人： Steven M. Cramer , James A. Moore , Amitava Kundu , Yufei Li , Guhan Jayaraman
发明人： Steven M. Cramer , James A. Moore , Amitava Kundu , Yufei Li , Guhan Jayaraman
IPC分类号： C07C217/08 , B01D15/42 , C07C215/40 , C07K1/18 , G01N30/02 , C07K1/14 , C07K1/16
CPC分类号： B01D15/422 , C07C215/40 , C07K1/18 , G01N30/02
摘要： A method for the purification of proteins by displacement chromatography on ion exchange media using low molecular weight displacers is disclosed. Several classes of low molecular weight anionic species are exemplified, including aromatic rings having sulfonic acid or carboxylic acid moieties attached thereon, sulfated sugar derivatives, anionic antibiotics, and dendrimeric polymers. Novel compounds useful as displacers are dendrimers of formula ##STR1## wherein R.sup.1 is lower alkyl, n is 2 to 6 and similar dendritic polymers based thereon.
摘要翻译： 公开了一种使用低分子量置换器在离子交换介质上通过置换色谱法纯化蛋白质的方法。 例举了几类低分子量阴离子物质，包括其上连接有磺酸或羧酸部分的芳香环，硫酸化糖衍生物，阴离子抗生素和树枝状聚合物。 用作置换剂的新型化合物是基于其的式和类似树枝状聚合物的树枝状大分子。
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公开(公告)号：US08788471B2
公开(公告)日：2014-07-22
申请号：US13483778
申请日：2012-05-30
IPC分类号： G06F17/30
CPC分类号： G06F17/30371 , G06F17/30008 , G06F17/303
摘要： A method for identifying matching transactions between two log files where each transaction includes one or more statements. Each log file record records the execution of a statement and includes a transaction identifier. Each record in turn in one log file is compared to an advancing window of records in the other log file. A first table contains associations of statements to transactions and transactions to statements for records in the window. If a match is found between a record in the one file and a record in the window, information associating partial transactions in the one file to potential transactions of the records in the window is added to a second table. If an end-of-transaction record is read from the one file, a best match is found between the ended transaction and the potential transactions based on information in the first and second tables.
摘要翻译： 一种用于识别两个日志文件之间的匹配事务的方法，其中每个事务包括一个或多个语句。 每个日志文件记录记录语句的执行并包括事务标识符。 将一个日志文件中的每个记录依次与其他日志文件中的前进记录窗口进行比较。 第一个表包含与事务和事务的语句关联到窗口中的记录的语句。 如果在一个文件中的记录和窗口中的记录之间找到匹配，则将一个文件中的部分事务与窗口中的记录的潜在事务关联的信息被添加到第二个表。 如果从一个文件读取结束交易记录，则基于第一和第二表中的信息，在结束的交易和潜在交易之间找到最佳匹配。
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公开(公告)号：US20130325826A1
公开(公告)日：2013-12-05
申请号：US13483778
申请日：2012-05-30
IPC分类号： G06F17/30
CPC分类号： G06F17/30371 , G06F17/30008 , G06F17/303
摘要： A method for identifying matching transactions between two log files where each transaction includes one or more statements. Each log file record records the execution of a statement and includes a transaction identifier. Each record in turn in one log file is compared to an advancing window of records in the other log file. A first table contains associations of statements to transactions and transactions to statements for records in the window. If a match is found between a record in the one file and a record in the window, information associating partial transactions in the one file to potential transactions of the records in the window is added to a second table. If an end-of-transaction record is read from the one file, a best match is found between the ended transaction and the potential transactions based on information in the first and second tables.
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公开(公告)号：US20130325829A1
公开(公告)日：2013-12-05
申请号：US13906374
申请日：2013-05-31
IPC分类号： G06F17/30
CPC分类号： G06F17/30371 , G06F17/30008 , G06F17/303
摘要： A method for identifying matching transactions between two log files where each transaction includes one or more statements. Each log file record records the execution of a statement and includes a transaction identifier. Each record in turn in one log file is compared to an advancing window of records in the other log file. A first table contains associations of statements to transactions and transactions to statements for records in the window. If a match is found between a record in the one file and a record in the window, information associating partial transactions in the one file to potential transactions of the records in the window is added to a second table. If an end-of-transaction record is read from the one file, a best match is found between the ended transaction and the potential transactions based on information in the first and second tables.
摘要翻译： 一种用于识别两个日志文件之间的匹配事务的方法，其中每个事务包括一个或多个语句。 每个日志文件记录记录语句的执行并包括事务标识符。 将一个日志文件中的每个记录依次与其他日志文件中的前进记录窗口进行比较。 第一个表包含与事务和事务的语句关联到窗口中的记录语句。 如果在一个文件中的记录和窗口中的记录之间找到匹配，则将一个文件中的部分事务与窗口中的记录的潜在事务关联的信息被添加到第二个表。 如果从一个文件读取结束交易记录，则基于第一和第二表中的信息，在结束的交易和潜在交易之间找到最佳匹配。
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