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公开(公告)号:US07977071B2
公开(公告)日:2011-07-12
申请号:US11628475
申请日:2005-06-02
申请人: Stewart Nuttal , Victor Streltsov , Katherine Merne Griffiths , Jennifer Ann Carmichael , Peter Hudson , Robert Alexander Irving , Joseph Noozhumurry Varghese , Miles Mackay Barraclough , David Peter Simmons , Kylie Anne Henderson
发明人: Stewart Nuttal , Victor Streltsov , Katherine Merne Griffiths , Jennifer Ann Carmichael , Peter Hudson , Robert Alexander Irving , Joseph Noozhumurry Varghese , Miles Mackay Barraclough , David Peter Simmons , Kylie Anne Henderson
CPC分类号: C07K16/464 , C07K14/461 , C07K16/00 , C07K2299/00 , C07K2317/20 , C07K2317/24 , C07K2317/56 , C07K2317/565
摘要: The present invention relates to immunoglobulin new antigen receptors (IgNARs) from fish and uses thereof. In particular, the present invention relates to modified IgNAR variable domains and to domains from members of the immunoglobulin superfamily that have been modified to include structural features derived from IgNAR variable domains.
摘要翻译: 本发明涉及来自鱼的免疫球蛋白新抗原受体(IgNAR)及其用途。 特别地,本发明涉及修饰的IgNAR可变结构域和来自免疫球蛋白超家族成员的结构域,其已被修饰以包括来自IgNAR可变结构域的结构特征。
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公开(公告)号:US20090148438A1
公开(公告)日:2009-06-11
申请号:US11628475
申请日:2005-06-02
申请人: Stewart Nuttal , Victor Streltsov , Katherine Merne Griffiths , Jennifer Ann Carmichael , Peter Hudson , Robert Alexander Irving , Joseph Noozhumurry Varghese , Miles MacKay Barraclough , David Peter Simmons , Kylie Anne Henderson
发明人: Stewart Nuttal , Victor Streltsov , Katherine Merne Griffiths , Jennifer Ann Carmichael , Peter Hudson , Robert Alexander Irving , Joseph Noozhumurry Varghese , Miles MacKay Barraclough , David Peter Simmons , Kylie Anne Henderson
IPC分类号: A61K39/395 , C07K16/18 , C40B40/08
CPC分类号: C07K16/464 , C07K14/461 , C07K16/00 , C07K2299/00 , C07K2317/20 , C07K2317/24 , C07K2317/56 , C07K2317/565
摘要: The present invention relates to immunoglobulin new antigen receptors (IgNARs) from fish and uses thereof. In particular, the present invention relates to modified IgNAR variable domains and to domains from members of the immunoglobulin superfamily that have been modified to include structural features derived from IgNAR variable domains.
摘要翻译: 本发明涉及来自鱼的免疫球蛋白新抗原受体(IgNAR)及其用途。 特别地,本发明涉及修饰的IgNAR可变结构域和来自免疫球蛋白超家族成员的结构域,其已被修饰以包括来自IgNAR可变结构域的结构特征。
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公开(公告)号:US20120003214A1
公开(公告)日:2012-01-05
申请号:US13157205
申请日:2011-06-09
申请人: Stewart Nuttall , Victor Streltsov , Katherine Merne Griffiths , Jennifer Ann Carmichael , Peter Hudson , Robert Alexander Irving , Joseph Noozhumurry Varghese , Miles Mackay Barraclough , David Peter Simmons , Kylie Anne Henderson
发明人: Stewart Nuttall , Victor Streltsov , Katherine Merne Griffiths , Jennifer Ann Carmichael , Peter Hudson , Robert Alexander Irving , Joseph Noozhumurry Varghese , Miles Mackay Barraclough , David Peter Simmons , Kylie Anne Henderson
IPC分类号: A61K39/395 , C40B40/08 , C07K16/00
CPC分类号: C07K16/464 , C07K14/461 , C07K16/00 , C07K2299/00 , C07K2317/20 , C07K2317/24 , C07K2317/56 , C07K2317/565
摘要: The present invention relates to immunoglobulin new antigen receptors (IgNARs) from fish and uses thereof. In particular, the present invention relates to modified IgNAR variable domains and to domains from members of the immunoglobulin superfamily that have been modified to include structural features derived from IgNAR variable domains.
摘要翻译: 本发明涉及来自鱼的免疫球蛋白新抗原受体(IgNAR)及其用途。 特别地,本发明涉及修饰的IgNAR可变结构域和来自免疫球蛋白超家族成员的结构域,其已被修饰以包括来自IgNAR可变结构域的结构特征。
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