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公开(公告)号：US06178356B1
公开(公告)日：2001-01-23
申请号：US09280128
申请日：1999-03-26
IPC分类号： A61N105
CPC分类号： A61N1/057 , A61N2001/0585
摘要： A body implantable lead for placement in a selected coronary vein includes a resilient retention structure for inhibiting displacement of the lead because of heart beat action, breathing or other body movement. The retention structure includes a plurality of resilient projections that are attached to the lead body and which are adapted to project at a predetermined acute angle to the axis of the lead body when unconstrained. Prior to being routed through the vascular system, the projections can be bonded to the lead body to provide a low profile with a biodegradable adhesive. Following exposure to body fluids, the adhesive dissolves, releasing the projections so that they can engage the walls of the vein in which the lead is disposed.
摘要翻译： 用于放置在所选择的冠状静脉中的身体可植入引线包括弹性保持结构，用于抑制由于心跳动作，呼吸或其他身体运动引起的位移。 保持结构包括多个弹性突起，其附接到引线主体并且适于在不受约束时以与引线主体的轴线成预定的锐角突出。 在被引导通过血管系统之前，突起可以结合到引线主体以通过可生物降解的粘合剂提供低轮廓。 在暴露于体液后，粘合剂溶解，释放突起使得它们可以与引导物置于其中的静脉的壁接合。
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公开(公告)号：US5931864A
公开(公告)日：1999-08-03
申请号：US27288
申请日：1998-02-20
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N2001/0585
摘要： A body implantable lead for placement in a selected coronary vein includes a resilient retention structure for inhibiting displacement of the lead because of heart beat action, breathing or other body movement. The retention structure includes a plurality of resilient projections that are attached to the lead body and which are adapted to project at a predetermined acute angle to the axis of the lead body when unconstrained. Prior to being routed through the vascular system, the projections can be bonded to the lead body to provide a low profile with a biodegradable adhesive. Following exposure to body fluids, the adhesive dissolves, releasing the projections so that they can engage the walls of the vein in which the lead is disposed.
摘要翻译： 用于放置在所选择的冠状静脉中的身体可植入引线包括弹性保持结构，用于抑制由于心跳动作，呼吸或其他身体运动引起的位移。 保持结构包括多个弹性突起，其附接到引线主体并且适于在不受约束时以与引线主体的轴线成预定的锐角突出。 在被引导通过血管系统之前，突起可以结合到引线主体以通过可生物降解的粘合剂提供低轮廓。 在暴露于体液后，粘合剂溶解，释放突起使得它们可以与引导物置于其中的静脉的壁接合。
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公开(公告)号：US06136021A
公开(公告)日：2000-10-24
申请号：US274621
申请日：1999-03-23
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N2001/0585
摘要： Expandable electrodes for intravascular leads permit the electrodes to be placed and retained in the vasculature of the left side of the heart. Such electrodes can be in the form of a balloon, an expandable wire coil, or other expandable shapes.
摘要翻译： 用于血管内引线的可扩展电极允许将电极放置并保留在心脏左侧的脉管系统中。 这种电极可以是气球，可膨胀线圈或其它可膨胀形状的形式。
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公开(公告)号：US06671560B2
公开(公告)日：2003-12-30
申请号：US10081436
申请日：2002-02-20
申请人： Randy W. Westlund , Bruce A. Tockman , Randall M. Peterfeso , John S. Greenland , Mary N. Hinders
发明人： Randy W. Westlund , Bruce A. Tockman , Randall M. Peterfeso , John S. Greenland , Mary N. Hinders
IPC分类号： A61N105
CPC分类号： A61N1/057 , A61B2017/22035 , A61M25/09 , A61M2025/09175 , A61N2001/0578
摘要： An improved guidewire for assisting in implantation of a cardiac lead includes three sections. The most distal zone is sufficiently floppy to prevent trauma to the vessel walls through which the guidewire and lead are inserted. An intermediate zone is generally stiffer and has a cross-section less than or equal to the cross-section of the distal zone. The third zone is stiffer yet and is joined to the intermediate zone by a shoulder. The shoulder cooperates with protrusions on the lead to transfer forces between the guidewire and lead. A removal wire having temporary locking device to lock the removal wire to the lead is employed to remove the guide catheter without moving the lead from its desired location. Lubricious coatings are also provided to reduce friction between the lead and guidewire.
摘要翻译： 用于辅助植入心脏引线的改进的导线包括三个部分。 最远端的区域是足够的软盘，以防止对引导线和引线插入的血管壁的创伤。 中间区通常较硬，横截面小于或等于远端区的横截面。 第三区域较硬，并通过肩部连接到中间区域。 肩部与导线上的突起配合，以在导丝和导线之间传递力。 使用具有临时锁定装置以将去除线锁定到引线的去除线去除引导导管而不将引线从其期望位置移动。 还提供润滑涂层以减少引线和导丝之间的摩擦。
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公开(公告)号：US06356791B1
公开(公告)日：2002-03-12
申请号：US09466266
申请日：1999-12-17
申请人： Randy W. Westlund , Randall M. Peterfeso , Mary N. Hinders , Bruce A. Tockman , John S. Greenland
发明人： Randy W. Westlund , Randall M. Peterfeso , Mary N. Hinders , Bruce A. Tockman , John S. Greenland
IPC分类号： A61N105
CPC分类号： A61N1/057 , A61B2017/22035 , A61M25/09 , A61M2025/09175 , A61N2001/0578
摘要： An improved guidewire for assisting in implantation of a cardiac lead includes three sections. The most distal zone is sufficiently floppy to prevent trauma to the vessel walls through which the guidewire and lead are inserted. An intermediate zone is generally stiffer and has a cross-section less than or equal to the cross-section of the distal zone. The third zone is stiffer yet and is joined to the intermediate zone by a shoulder. The shoulder cooperates with protrusions on the lead to transfer forces between the guidewire and lead. A removal wire having temporary locking means to lock the removal wire to the lead is employed to remove the guide catheter without moving the lead from its desired location. Lubricious coatings are also provided to reduce friction between the lead and guidewire.
摘要翻译： 用于辅助植入心脏引线的改进的导线包括三个部分。 最远端的区域是足够的软盘，以防止对引导线和引线插入的血管壁的创伤。 中间区通常较硬，横截面小于或等于远端区的横截面。 第三区域较硬，并通过肩部连接到中间区域。 肩部与导线上的突起配合，以在导丝和导线之间传递力。 采用具有将去除线锁定到引线上的临时锁定装置的移除线去除引导导管，而不将引线从其期望的位置移动。 还提供润滑涂层以减少引线和导丝之间的摩擦。
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公开(公告)号：US5951597A
公开(公告)日：1999-09-14
申请号：US59786
申请日：1998-04-14
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N2001/0585
摘要： An intravenous lead for use with a cardiac device for implantation in the coronary venous system of the heart includes a lead body that is adapted to be routed through the vascular system into the coronary sinus with the distal end portion of the lead placed in the great cardiac vein or branch vein. The lead body includes a fixation member disposed just proximal of its tip. The fixation member comprises a radially expandable polymeric matrix that incorporates an osmotic agent so that when placed in a aqueous medium it will swell. Thus, when placed in a cardiac vein, the swelling of the fixation member will anchor the lead against longitudinal displacement due to body motion, blood flow and the beating action of the heart.
摘要翻译： 用于心脏装置用于植入心脏冠状静脉系统的静脉导管包括引线体，其适于通过血管系统引导到冠状窦中，将引线的远端部分放置在大心脏中 静脉或分支静脉。 引线体包括设置在其尖端附近的固定部件。 固定构件包括可渗透的聚合物基质，其包含渗透剂，使得当放置在水性介质中时，其将溶胀。 因此，当放置在心静脉中时，固定构件的肿胀将由于身体运动，血液流动和心脏的打动作用而使引线抵抗纵向移位。
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公开(公告)号：US5803928A
公开(公告)日：1998-09-08
申请号：US788647
申请日：1997-01-24
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N2001/058 , A61N2001/0585
摘要： Intravenous cardiac leads having at least one electrode intended to be implanted within the coronary artery are disclosed. Also disclosed are structures and techniques for advancing such leads through the atrium and coronary sinus into the coronary veins overlaying the left ventricle.
摘要翻译： 公开了具有至少一个待植入冠状动脉的电极的静脉内心脏引线。 还公开了用于将这种引线通过心房和冠状窦推进到覆盖左心室的冠状静脉的结构和技术。
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公开(公告)号：US06939327B2
公开(公告)日：2005-09-06
申请号：US10140540
申请日：2002-05-07
CPC分类号： A61M25/0668
摘要： A peel-away sheath for a catheter includes at least one weakened area in a non-longitudinal pattern, such as a helical pattern, along the length of the sheath. One embodiment of a catheter sheath includes a tube having at least one pull wire integrally located within its wall. Another embodiment of a catheter sheath includes a tube having at least one integral lumen within its wall. The integral lumen may house a filling material. One embodiment of a catheter may include a first sheath which is positioned within a second sheath, with each of the first and second sheaths having at least one weakened area along its length. A reinforcing guide for a guide catheter includes a tube having a lumen with a diameter at least as large as the guide catheter diameter. The reinforcing guide includes a gap with a width which is less than the guide catheter diameter.
摘要翻译： 用于导管的剥离鞘包括至少一个沿着护套长度的非纵向图案的弱化区域，例如螺旋图案。 导管护套的一个实施例包括具有整体地位于其壁内的至少一个拉线的管。 导管护套的另一实施例包括在其壁内具有至少一个整体腔的管。 整体腔可容纳填充材料。 导管的一个实施例可以包括定位在第二护套内的第一护套，其中第一和第二护套中的每一个沿其长度具有至少一个弱化区域。 用于引导导管的加强引导件包括具有直径至少与引导导管直径一样大的内腔的管。 加强引导件包括宽度小于引导导管直径的间隙。
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公开(公告)号：US6122552A
公开(公告)日：2000-09-19
申请号：US262155
申请日：1999-03-03
申请人： Bruce A. Tockman , Randy W. Westlund , Stuart R. Chastain , Bruce M. Wilson , John A. Greenland , Jon A. Becker
发明人： Bruce A. Tockman , Randy W. Westlund , Stuart R. Chastain , Bruce M. Wilson , John A. Greenland , Jon A. Becker
CPC分类号： A61M25/10 , A61M2025/0681 , A61M2025/1052 , A61N2001/0578
摘要： An apparatus for positioning a cardiac lead in the vasculature of the heart includes a guide catheter, a sleeve and a guidewire. The guide catheter has an inflatable balloon at its distal end and a central lumen open distally to the exterior of the catheter for injection of dye or advancement of a guidewire through the guide catheter and past its distal end. The guide sleeve replaces the guide catheter once the guidewire is in position so that a lead can be advanced over the guidewire with the sleeve.
摘要翻译： 用于将心脏引线定位在心脏的脉管系统中的装置包括导向导管，套管和导丝。 引导导管在其远端处具有可充气气囊，并且中心腔向远侧方向朝向导管外部打开，用于注射染料或引导线通过引导导管并通过其远端。 一旦导丝线就位，引导套筒即可取代导向导管，以便引导件可以在套管之间在引导线上前进。
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公开(公告)号：US08313478B2
公开(公告)日：2012-11-20
申请号：US12984965
申请日：2011-01-05
IPC分类号： A61M25/01
CPC分类号： A61M25/0041 , A61M25/0105 , A61M25/0136
摘要： A catheter assembly for cannulating an ostium of a coronary sinus of a heart comprises an outer catheter member and an inner catheter member. The outer catheter member has a distal end portion including a deflectable distal end and a lumen extending through the deflectable distal end, wherein the distal end portion includes regions of varying stiffness and has a pre-formed curvature. The inner catheter member is slidably and rotatably disposed within the lumen of the outer catheter member, and has a distal end portion including a distal end, and a lumen extending through the distal end. The distal end portion of the inner catheter member has regions of varying stiffness and a pre-formed curvature. The outer and inner catheter members are configured such that relative translation and rotation of the outer and inner catheter members causes the distal end of the outer catheter member to assume a plurality of two and three dimensional shapes.
摘要翻译： 用于插入心脏冠状窦口的导管组件包括外导管构件和内导管构件。 外导管构件具有包括可偏转远端和延伸穿过可偏转远端的内腔的远端部分，其中远端部分包括具有变化刚度的区域并且具有预先形成的曲率。 内导管构件可滑动地且可旋转地设置在外导管构件的内腔内，并且具有包括远端的远端部分和延伸穿过远端的内腔。 内导管构件的远端部分具有变化的刚度和预先形成的曲率的区域。 外导管构件和内导管构件被构造成使得外导管构件和内导管构件的相对平移和旋转导致外导管构件的远端呈现多个二维和三维形状。
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