摘要:
Novel compounds belonging to the class of oxazolidinones possessing potent antimycobacterial properties especially useful in the treatment of acid fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium-intracellular complex, M. fortuitum and M. kansai. The compound and its pharmaceutically acceptable salts act as antibacterial agents. Also mentioned is a method for inhibiting growth of mycobacterial cells as well as a method of treating mycobacterial conditions such as Mycobacterium tuberculosis, drug resistant Mycobacterium tuberculosis, Mycobacterium avium-intracellular complex, M. fortuitum and M. kansai., including administering an antimycobacterially effective amount of the compound and/or pharmaceutically acceptable salts. There is also mentioned a process for the manufacture of the compound or its pharmaceutically acceptable salts.
摘要:
Novel pyrrole derivatives of formula (I) and their pharmaceutically acceptable acid addition salts having superior antimycobacterial activity against clinically sensitive as well as resistant strains of Mycobacterium tuberculosis as well as having lesser toxicity compared to known compounds. The use of the novel compounds of formula (I) for treatment of latent tuberculosis including Multi Drug Resistant Tuberculosis (MDR TB). The methods for preparation of the novel compounds, pharmaceutical compositions containing the novel compounds and method of treating MDR TB by administration of compounds of formula (I).
摘要:
Novel pyrrole derivatives of formula (I) and their pharmaceutically acceptable acid addition salts having superior antimycobacterial activity against clinically sensitive as well as resistant strains of Mycobacterium tuberculosis as well as having lesser toxicity compared to known compounds. The use of the novel compounds of formula (I) for treatment of latent tuberculosis including Multi Drug Resistant Tuberculosis (MDR TB). The methods for preparation of the novel compounds, pharmaceutical compositions containing the novel compounds and method of treating MDR TB by administration of compounds of formula (I).
摘要:
Novel pyrrole derivatives of formula (I) and their pharmaceutically acceptable acid addition salts having superior antimycobacterial activity against clinically sensitive as well as resistant strains of Mycobacterium tuberculosis as well as having lesser toxicity compared to known compounds. The use of the novel compounds of formula (I) for treatment of latent tuberculosis including Multi Drug Resistant Tuberculosis (MDR TB). The methods for preparation of the novel compounds, pharmaceutical compositions containing the novel compounds and method of treating MDR TB by administration of compounds of formula (I).
摘要:
A second link in a network is reconfigured after failure of a first link, so that multiple-link failures may be survived. After receipt of an OSPF link state advertisement (LSA) indicating use of a backup path bl after the failure of link l, new backup paths are determined for each impacted link (x,y) that has a backup path sharing one or more links with the backup path bl. The new backup paths are computed while ignoring the failed link l, the impacted link (x,y), and links common to the backup paths b(x,y) and bl. The LSA protocol is modified to accommodate information used in determining whether a link is an impacted link.
摘要:
A memory circuit includes a memory cell configured to be re-writable. A write enable circuit is configured to enable writing a signal via a pair of bit lines to the memory cell depending on a write signal. A charge supply circuit is configured to supply a charge to at least one of the pair of bit lines. A charge supply controller is configured to control the charge supply circuit to disable the supply of charge and couple the write enable circuit to at least one of the pair of bit lines after a first determined period following the reception of the write signal.
摘要:
A second link in a network is reconfigured after failure of a first link, so that multiple-link failures may be survived. After receipt of an OSPF link state advertisement (LSA) indicating use of a backup path bl after the failure of link l, new backup paths are determined for each impacted link (x,y) that has a backup path sharing one or more links with the backup path bl. The new backup paths are computed while ignoring the failed link l, the impacted link (x,y), and links common to the backup paths b(x,y) and bl. The LSA protocol is modified to accommodate information used in determining whether a link is an impacted link.
摘要:
Systems and methods are described that that dynamically configure high-speed data link lightpaths between access routers and backbone routers at geographically dispersed locations to reassign traffic when a backbone router fails or is removed from service. Embodiments reduce the quantity of backbone router ports used in dual backbone router-homed networks.
摘要:
An embodiment of the invention is a method of allocating protection path resources including obtaining a link vector for a plurality of protection paths. The link vector includes a plurality of link vector elements. A proposed link vector is determined for each of the protection paths. The proposed link vector includes a plurality of proposed link vector elements and is indicative of allocating a respective protection path to a working path. A link cost is determined based on the proposed link vector and the obtained link vector. A path cost is determined for at least two protection paths based on the past cost.
摘要:
A method of generating a set of test sequences for evaluating interoperability of a number of interconnected communication systems with respect to a desired mode of communication between a first end user and a second end user. A number of operational states that are required of the communication systems to implement the desired mode of operation between the two end users is determined, wherein each state pertains to a first operation of a first gateway system associated with the first end user and a corresponding second operation of a second gateway system associated with the second end user. The interconnected communication systems are tested by causing the systems to perform specified transitions between pairs of at least some of the operational states.