公开(公告)号：USPP16747P3

公开(公告)日：2006-07-04

申请号：US10840289

申请日：2004-05-07

申请人： Suman P. S. Khanuja ,  Sushil Kumar ,  Ajit K. Shasany ,  Sunita Dhawan ,  Mahendra P. Darokar ,  Arun K. Tripathy ,  Sarita Satapathy ,  Tiruppadiripuliyur R. S. Kumar ,  Vivek K. Gupta ,  Arvind K. Tripathi ,  Soumya Awasthi ,  Veena Prajapati ,  Ali A. Naqvi ,  Krishna K. Agrawal ,  Janak R. Bahl ,  Anil K. Singh ,  Ateeque Ahmed ,  Ravi P. Bansal ,  Alok Krishna ,  Dharmendra Saikia

发明人： Suman P. S. Khanuja ,  Sushil Kumar ,  Ajit K. Shasany ,  Sunita Dhawan ,  Mahendra P. Darokar ,  Arun K. Tripathy ,  Sarita Satapathy ,  Tiruppadiripuliyur R. S. Kumar ,  Vivek K. Gupta ,  Arvind K. Tripathi ,  Soumya Awasthi ,  Veena Prajapati ,  Ali A. Naqvi ,  Krishna K. Agrawal ,  Janak R. Bahl ,  Anil K. Singh ,  Ateeque Ahmed ,  Ravi P. Bansal ,  Alok Krishna ,  Dharmendra Saikia

IPC分类号： A01H5/00

CPC分类号： A01H5/12

摘要： The present invention relates to the development of a novel multiutility vigorously growing robust mint plant ‘Ganga’ of Mentha spicata L. var. viridis producing essential oil exhibiting anti-insect and anti-microbial activities and useful for agrochemical and pharmaceutical purposes.

摘要翻译： 本发明涉及一种新型多功能强力生长强壮薄荷植物“芒果”的发展。 具有抗昆虫和抗微生物活性的生物精油，用于农业化学和制药目的。

公开(公告)号：US20050044600P1

公开(公告)日：2005-02-24

申请号：US10840289

申请日：2004-05-07

申请人： Suman Khanuja ,  Sushil Kumar ,  Ajit Shasany ,  Sunita Dhawan ,  Mahendra Darokar ,  Arun Tripathy ,  Sarita Satapathy ,  Tiruppadiripuliyur Kumar ,  Vivek Gupta ,  Arvind Tripathi ,  Soumya Awasthi ,  Veena Prajapati ,  Ali Naqvi ,  Krishna Agrawal ,  Janak Bahl ,  Anil Singh ,  Ateeque Ahmed ,  Ravi Bansal ,  Alok Krishna ,  Dharmendra Saikia

发明人： Suman Khanuja ,  Sushil Kumar ,  Ajit Shasany ,  Sunita Dhawan ,  Mahendra Darokar ,  Arun Tripathy ,  Sarita Satapathy ,  Tiruppadiripuliyur Kumar ,  Vivek Gupta ,  Arvind Tripathi ,  Soumya Awasthi ,  Veena Prajapati ,  Ali Naqvi ,  Krishna Agrawal ,  Janak Bahl ,  Anil Singh ,  Ateeque Ahmed ,  Ravi Bansal ,  Alok Krishna ,  Dharmendra Saikia

IPC分类号： A01H5/12 ,  A01H5/00 ,  A23L1/28 ,  A23L2/02 ,  A23P1/00

CPC分类号： A01H5/12

摘要： The present invention relates to the development of a novel multiutility vigorously growing robust mint plant ‘Ganga’ of Mentha spicata L. var. viridis producing essential oil exhibiting anti-insect and anti-microbial activities and useful for agrochemical and pharmaceutical purposes.

摘要翻译： 本发明涉及一种新型多功能强力生长强壮薄荷植物“芒果”的发展。 具有抗昆虫和抗微生物活性的生物精油，用于农业化学和制药目的。

公开(公告)号：US06514541B2

公开(公告)日：2003-02-04

申请号：US09536124

申请日：2000-03-28

申请人： Suman Preet Singh Khanuja ,  Suchi Srivastava ,  Ajit Kumar Shasney ,  Mahendra Pandurang Darokar ,  Tiruppadiripuliyur Ranganathan Santha Kumar ,  Krishna Kumar Agarwal ,  Ateeque Ahmed ,  Nirmal Kumar Patra ,  Prachi Sinha ,  Sunita Dhawan ,  Dharmendra Saikia ,  Sushil Kumar

发明人： Suman Preet Singh Khanuja ,  Suchi Srivastava ,  Ajit Kumar Shasney ,  Mahendra Pandurang Darokar ,  Tiruppadiripuliyur Ranganathan Santha Kumar ,  Krishna Kumar Agarwal ,  Ateeque Ahmed ,  Nirmal Kumar Patra ,  Prachi Sinha ,  Sunita Dhawan ,  Dharmendra Saikia ,  Sushil Kumar

IPC分类号： A61K3578

CPC分类号： A61K36/23 ,  A61K36/534 ,  Y10S514/924 ,  A61K2300/00

摘要： A formulation useful in the treatment of drug resistant bacterial infections comprising an effective amount of thymol obtained from the plant Trachyspermum ammi, mint oil containing an appropriate amount of monoterpenes obtained from a hybrid of Mentha spicata and Mentha arvensis, and conventional additives. A method for producing the formulation by mixing the above ingredients and a method for the treatment of drug resistance in a patient by administration of a therapeutically effective amount of the formulation.

摘要翻译： 一种可用于治疗耐药性细菌感染的制剂，其包含从植物Trachyspermum ammi获得的有效量的百里酚，含有从Mentha spicata和Mentha arvensis的杂种获得的适量的单萜和常规添加剂的薄荷油。 通过施用治疗有效量的制剂，通过混合上述成分和用于治疗患者耐药性的方法来制备制剂的方法。

公开(公告)号：US07262004B1

公开(公告)日：2007-08-28

申请号：US09487405

申请日：2000-01-18

申请人： Suman Preet Singh Khanuja ,  Ajit Kumar Shasany ,  Sunita Dhawan ,  Mahendra Pandurang Darokar ,  Sarita Satapathy ,  Tiruppadiripuliyur Ranganathan Santha Kumar ,  Dharmendra Saikia ,  Nirmal Kumar Patra ,  Janak Raj Bahl ,  Arun Kumar Tripathy ,  Sushil Kumar

发明人： Suman Preet Singh Khanuja ,  Ajit Kumar Shasany ,  Sunita Dhawan ,  Mahendra Pandurang Darokar ,  Sarita Satapathy ,  Tiruppadiripuliyur Ranganathan Santha Kumar ,  Dharmendra Saikia ,  Nirmal Kumar Patra ,  Janak Raj Bahl ,  Arun Kumar Tripathy ,  Sushil Kumar

IPC分类号： C12Q1/68

CPC分类号： A01H1/06 ,  A01H1/04 ,  A01H4/005 ,  A01H4/008 ,  A01H5/12

摘要： An in vitro screening method for identifying insect tolerant genotypes or clones is described. The method comprises growing plantlets in an in vitro system, screening the plantlets for molecular variation of somaclones using RAPD analysis in vitro, selecting the somaclones having molecular variation, exposing the somaclones to insect larvae or nymphs and identifying the surviving somaclones.

摘要翻译： 描述了用于鉴定耐受性基因型或克隆的体外筛选方法。 该方法包括在体外系统中种植小植株，在体外使用RAPD分析来筛选小鼠的分子变异的小植株，选择具有分子变异性的体细胞，将宿体菌暴露于昆虫幼虫或若虫并鉴定存活的体细胞。

公开(公告)号：USPP14538P2

公开(公告)日：2004-02-17

申请号：US09482645

申请日：2000-01-18

申请人： Suman Preet Singh Khanuja ,  Ajit Kumar Shasany ,  Sunita Dhawan ,  Mahendra Pandurang Darokar ,  Sarita Satapathy ,  Tiruppadiripuliyur Ranganathan Santha Kumar ,  Dharmendra Saikia ,  Nirmal Kumar Patra ,  Janak Raj Bahl ,  Arun Kumar Tripathy ,  Sushil Kumar

发明人： Suman Preet Singh Khanuja ,  Ajit Kumar Shasany ,  Sunita Dhawan ,  Mahendra Pandurang Darokar ,  Sarita Satapathy ,  Tiruppadiripuliyur Ranganathan Santha Kumar ,  Dharmendra Saikia ,  Nirmal Kumar Patra ,  Janak Raj Bahl ,  Arun Kumar Tripathy ,  Sushil Kumar

IPC分类号： A01H500

CPC分类号： A01H5/02

摘要： The present invention relates to a novel, insect tolerant, high yielding essential oil and menthol yielding mint plant named ‘Sambhav’, which is a cultivar of Mentha arvensis L.. The mint plant of the present invention has been developed as a result of planned experiments which devised a procedure for early selection of somaclonal variants at the in vitro stage of the variety of Mentha arvensis.

摘要翻译： 本发明涉及一种新颖的耐昆虫高产精油和薄荷醇，产生名为“Sambhav”的薄荷植物，它是薄荷茶的品种。本发明的薄荷植物是由计划的结果而开发的 在Mentha arvensis的体外阶段设计了用于早期选择体细胞克隆变体的程序的实验。

公开(公告)号：US06824795B2

公开(公告)日：2004-11-30

申请号：US10322731

申请日：2002-12-19

申请人： Suman Preet Singh Khanuja ,  Suchi Srivastava ,  Ajit Kumar Shasney ,  Mahendra Pandurang Darokar ,  Tiruppadiripuliyur Ranganathan Santha Kumar ,  Krishna Kumar Agarwal ,  Ateeque Ahmed ,  Nirmal Kumar Patra ,  Prachi Sinha ,  Sunita Dhawan ,  Dharmendra Saikia ,  Sushil Kumar

发明人： Suman Preet Singh Khanuja ,  Suchi Srivastava ,  Ajit Kumar Shasney ,  Mahendra Pandurang Darokar ,  Tiruppadiripuliyur Ranganathan Santha Kumar ,  Krishna Kumar Agarwal ,  Ateeque Ahmed ,  Nirmal Kumar Patra ,  Prachi Sinha ,  Sunita Dhawan ,  Dharmendra Saikia ,  Sushil Kumar

IPC分类号： A61K3578

CPC分类号： A61K36/23 ,  A61K36/534 ,  A61K2300/00

摘要： A formulation useful in the treatment of drug resistant bacterial infections comprising an effective amount of thymol obtained from the plant Trachyspermum ammi, mint oil containing an appropriate amount of monoterpenes obtained from a hybrid of Mentha spicata and Mentha arvensis, and conventional additives. A method for producing the formulation by mixing the above ingredients and a method for the treatment of drug resistance in a patient by administration of a therapeutically effective amount of the formulation.

摘要翻译： 一种可用于治疗耐药性细菌感染的制剂，其包含从植物Trachyspermum ammi获得的有效量的百里酚，含有从Mentha spicata和Mentha arvensis的杂种获得的适量的单萜和常规添加剂的薄荷油。 通过施用治疗有效量的制剂，通过混合上述成分和用于治疗患者耐药性的方法来制备制剂的方法。

公开(公告)号：US06423541B1

公开(公告)日：2002-07-23

申请号：US09531768

申请日：2000-03-21

申请人： Suman Preet Singh Khanuja ,  Ajit Kumar Shasany ,  Sunita Dhawan ,  Mahendra Pandurang Darokar ,  Tiruppadiripuliyur Ranganathan Santha Kumar ,  Dharmendra Saikia ,  Arif Ali Naqui ,  Sushil Kumar

发明人： Suman Preet Singh Khanuja ,  Ajit Kumar Shasany ,  Sunita Dhawan ,  Mahendra Pandurang Darokar ,  Tiruppadiripuliyur Ranganathan Santha Kumar ,  Dharmendra Saikia ,  Arif Ali Naqui ,  Sushil Kumar

IPC分类号： C12N500

CPC分类号： A01H1/04 ,  A01H5/12

摘要： The invention provides a rapid in vitro method for selection of menthol rich mint genotypes from a large population of independent clones, said method comprising the steps of (i) raising a heterogeneous population of Mentha arvensis clones in vitro or by vegetative methods, (ii) transferring the plantlets/shoots to a basal medium, containing cytotoxic compounds in an amount sufficient to cause toxic effect in more than 95% of the clones, (iii) selecting surviving clones, their hardening in the glasshouse, transfer to field, reconfirmation of menthol tolerance through repeated in vitro assays, and (iv) multiplying selected clones and confirming genetic uniformity through RAPD analysis.

摘要翻译： 本发明提供了一种用于从大量独立克隆中选择富含薄荷醇的薄荷基因型的快速体外方法，所述方法包括以下步骤：（i）在体外或通过营养方法提高薄荷亚种克隆的异质群体，（ii） 将小植株/芽转移到基础培养基中，其含有足以在超过95％的克隆中引起毒性作用的细胞毒性化合物，（iii）选择存活的克隆，其在温室中的硬化，转移到野外，再次确认薄荷醇 通过重复体外测定的耐受性，以及（iv）通过RAPD分析来扩增选定的克隆并证实遗传均一性。

公开(公告)号：US06420174B1

公开(公告)日：2002-07-16

申请号：US09536379

申请日：2000-03-28

申请人： Suman Preet Singh Khanuja ,  Ajit Kumar Shasany ,  Sunita Dhawan ,  Mahendra Pandurang Darokar ,  Tiruppadiripuliyur Ranganathan Santha Kumar ,  Dharmendra Saikia ,  Sushil Kumar

发明人： Suman Preet Singh Khanuja ,  Ajit Kumar Shasany ,  Sunita Dhawan ,  Mahendra Pandurang Darokar ,  Tiruppadiripuliyur Ranganathan Santha Kumar ,  Dharmendra Saikia ,  Sushil Kumar

IPC分类号： C12N500

CPC分类号： A01H4/005 ,  A01H4/008 ,  C12N5/04

摘要： The present invention is related to a method of producing organogenetic tissues from a plant of the genus Mentha, said method comprising the steps of culturing an explant from a plant of genus Mentha on an initiation medium in the presence of 400 to 600 lux light at a temperature of 23-27° C., with 16 hours of photoperiod, to obtain calli, transferring the calli to a basal medium comprising minerals and vitamins to ensure development of shoots, and culturing the shoots in a medium substantially free of growth hormones and containing menthol in a concentration of about 80 &mgr;g ml−1 to ensure root formation.

摘要翻译： 本发明涉及一种从薄荷属植物生产有机发育组织的方法，所述方法包括以下步骤：在400至600勒克斯光的存在下，在起始培养基上培养来自芒特属植物的外植体， 温度为23-27℃，光周期为16小时，以获得愈伤组织，将愈伤组织转移到包含矿物质和维生素的基础培养基中，以确保芽的发育，并在基本上不含生长激素的培养基中培养芽，并含有 浓缩约80毫升ml-1的薄荷醇以确保根形成。

公开(公告)号：US06252114B1

公开(公告)日：2001-06-26

申请号：US09535121

申请日：2000-03-24

申请人： Sunil Kumar Chattopadhyay ,  Koneni Venkata Sashidhara ,  Vinayak Tripathi ,  Arun Kumar Tripathi ,  Veena Prajapati ,  Sushil Kumar

发明人： Sunil Kumar Chattopadhyay ,  Koneni Venkata Sashidhara ,  Vinayak Tripathi ,  Arun Kumar Tripathi ,  Veena Prajapati ,  Sushil Kumar

IPC分类号： C07C20700

CPC分类号： C07C43/225 ,  C07C217/62

摘要： The invention provides a process for the preparation of 4-(p-methoxyphenyl)-2-aminobutane represented by structural formula (1) as shown herein below: [C11H17ON=4-(p-methoxy phenyl)-2-amino butane] said process comprising the steps of, (a) isolating a phenolic compound 4-hydroxyphenyl)-butan-2-ol from the leaves of Taxus wallichiana by known methods, (b) treating the phenolic compound in aqueous mineral acid to obtain a phenolic halide derivative, (c) converting the phenolic halide derivative into its methyl ether by treating it with a methating agent, (d) reacting the methyl ether halide with azide to obtain an azido derivative, and (e) hydrogenating the azido compound to obtain 4-(p-methoxyphenyl)-2-aminobutane.

摘要翻译： 本发明提供了制备由结构式（1）表示的4-（对甲氧基苯基）-2-氨基丁烷的方法，如下所示：[C 11 H 17 ON = 4-（对甲氧基苯基）-2-氨基丁烷]所述 方法包括以下步骤：（a）通过已知方法从紫杉属的叶子中分离酚类化合物4-羟基苯基 - 丁-2-醇，（b）在无机酸水溶液中处理酚类化合物以获得酚卤化物衍生物 （c）通过用甲基化剂处理酚卤化物衍生物转化成甲基醚，（d）使甲基醚卤化物与叠氮化物反应得到叠氮基衍生物，和（e）氢化叠氮化合物得到4-（ 对甲氧基苯基）-2-氨基丁烷。

公开(公告)号：US06441205B1

公开(公告)日：2002-08-27

申请号：US09574543

申请日：2000-05-19

申请人： Sunil Kumar Chattopadhyay ,  Koneni Venkata Sashidhara ,  Vinayak Tripathi ,  Arun Kumar Tripathi ,  Veena Prajapati ,  Sushil Kumar

发明人： Sunil Kumar Chattopadhyay ,  Koneni Venkata Sashidhara ,  Vinayak Tripathi ,  Arun Kumar Tripathi ,  Veena Prajapati ,  Sushil Kumar

IPC分类号： C07C24706

CPC分类号： C07C217/62 ,  A01N33/10

摘要： The invention provides a novel compound 4-(p-methoxy-phenyl)-2-aminobutane exhibiting growth inhibition and antifeedant activity and represented by the structural formula. C11H17ON=4-(p-methoxy phenyl)-2-amino butane and an insecticidal composition comprising an effective amount of the novel compound and appropriate adjuvant.

摘要翻译： 本发明提供一种新的化合物4-（对甲氧基 - 苯基）-2-氨基丁烷，其具有生长抑制作用和拒食活性，由结构式C 11 H 17 ON = 4-（对甲氧基苯基）-2-氨基丁烷和杀虫组合物 包含有效量的新化合物和适当的佐剂。