公开(公告)号：US5763631A

公开(公告)日：1998-06-09

申请号：US667133

申请日：1996-06-20

申请人： Sung Chun Kim ,  Nakyen Choy ,  Chang Sun Lee ,  Ho I. Choi ,  Jong Sung Koh ,  Heungsik Yoon ,  Chi Hyo Park ,  Sang Soo Kim ,  Young Chan Son

发明人： Sung Chun Kim ,  Nakyen Choy ,  Chang Sun Lee ,  Ho I. Choi ,  Jong Sung Koh ,  Heungsik Yoon ,  Chi Hyo Park ,  Sang Soo Kim ,  Young Chan Son

IPC分类号： A61K31/335 ,  A61K31/00 ,  A61K31/336 ,  A61K38/00 ,  A61P31/00 ,  A61P31/12 ,  A61P31/18 ,  C07C213/02 ,  C07C217/08 ,  C07C269/04 ,  C07C271/20 ,  C07C271/22 ,  C07D301/02 ,  C07D303/36 ,  C07D303/38 ,  C07D303/40 ,  C07D303/46 ,  C07D405/12 ,  C07D405/14 ,  C07D493/08 ,  C07K5/02 ,  C07K5/06 ,  C07K5/065 ,  C07K5/078 ,  C07K7/02 ,  C07D303/08 ,  C07D215/38 ,  C07D235/04 ,  C07D413/00

CPC分类号： C07D303/38 ,  C07C217/08 ,  C07C271/20 ,  C07C271/22 ,  C07D303/36 ,  C07D303/46 ,  C07D405/12 ,  C07D405/14 ,  C07D493/08 ,  C07K5/0207 ,  C07K5/06026 ,  C07K5/06078 ,  C07K5/06139 ,  C07K7/02 ,  A61K38/00 ,  C07C2101/14

摘要： Cis-epoxide compounds of formula (I-3) and pharmaceutically acceptable salts, hydrates and solvates thereof: ##STR1## wherein: R.sup.1 is a cycloalkyl, or arly-substituted lower alkyl group; K and J are independently a group having the formula of ##STR2## wherein R.sup.18 is a lower alkyl group optionally substituted with an aryl radical; X is O, NH, or N--CH.sub.3 ; and R.sup.19 is an aromatic hetercyclic sysstem containing a nitrogen atom in its ring, or a lower alkyl group optionally substituted with an aryl radical, or a hydrogen; G is an amino acid which is linked to K-- and ##STR3## by peptide bonds in formula (I-3); Q is an amino acid which is linked to by peptide bonds in formula (I-3), or a group having the formula of wherein R.sup.20 is a lower alkyl group optionally substituted with an aromatic radical; and Y is CH.sub.2, O or NH; and r is 0 or 1, except that Q is a group having the formula of r is 0.

摘要翻译： 式（I-3）的顺式环氧化合物及其药学上可接受的盐，水合物和溶剂化物：其中：R1是环烷基或芳取代的低级烷基; K和J独立地是具有下式的基团：其中R18是任选被芳基取代的低级烷基; X是O，NH或N-CH 3; R19是在其环中含有氮原子的芳族杂环体系，或任选被芳基取代的低级烷基或氢; G是通过式（I-3）中的肽键与K-和连接的氨基酸; Q是通过式（I-3）中的肽键连接的氨基酸或具有下式的基团：其中R 20是任选被芳族基团取代的低级烷基; 并且Y是CH 2，O或NH; 并且r为0或1，除了Q是具有式r的基团为0。

公开(公告)号：US5744621A

公开(公告)日：1998-04-28

申请号：US667888

申请日：1996-06-20

申请人： Sung Chun Kim ,  Nakyen Choy ,  Chang Sun Lee ,  Young Chan Son ,  Ho Il Choi ,  Jong Sung Koh ,  Heungsik Yoon ,  Chi Hyo Park ,  Sang Soo Kim

发明人： Sung Chun Kim ,  Nakyen Choy ,  Chang Sun Lee ,  Young Chan Son ,  Ho Il Choi ,  Jong Sung Koh ,  Heungsik Yoon ,  Chi Hyo Park ,  Sang Soo Kim

IPC分类号： A61K31/335 ,  A61K31/00 ,  A61K31/336 ,  A61K38/00 ,  A61P31/00 ,  A61P31/12 ,  A61P31/18 ,  C07C213/02 ,  C07C217/08 ,  C07C269/04 ,  C07C271/20 ,  C07C271/22 ,  C07D301/02 ,  C07D303/36 ,  C07D303/38 ,  C07D303/40 ,  C07D303/46 ,  C07D405/12 ,  C07D405/14 ,  C07D493/08 ,  C07K5/02 ,  C07K5/06 ,  C07K5/065 ,  C07K5/078 ,  C07K7/02 ,  C07D303/08 ,  C07D215/38 ,  C07D265/30

CPC分类号： C07D303/38 ,  C07C217/08 ,  C07C271/20 ,  C07C271/22 ,  C07D303/36 ,  C07D303/46 ,  C07D405/12 ,  C07D405/14 ,  C07D493/08 ,  C07K5/0207 ,  C07K5/06026 ,  C07K5/06078 ,  C07K5/06139 ,  C07K7/02 ,  A61K38/00 ,  C07C2101/14

摘要： Cis-epoxide compounds of formula (I-1) and pharmaceutically acceptable salts, hydrates and solvates thereof: ##STR1## wherein: R.sup.1 is a cycloalkyl, or aryl-substituted lower alkyl group; A is a functionalized acyl group of the formula ##STR2## wherein R.sup.2 is a C.sub.1-4 alkyl, or amide-substituted C.sub.1-2 alkyl group; R.sup.3 is a C.sub.1-4 alkoxy, aryloxyalkyl or arylalkoxy, or a nitrogen-containing aromatic radical, or a lower alkoxy group substituted with a nitrogen-containing aromatic radical, or a radical having the formula of ##STR3## wherein R.sup.4 is a hydrogen or a methyl group and R.sup.5 is an alkyl group substituted with a nitrogen-containing aromatic radical; and m is 0 or 1; and B is a functionalized amino group of the formula ##STR4## wherein R.sup.8 and R.sup.9 are independently a C.sub.1-4 alkyl group optionally substituted with an aromatic radical, or an aromatic group.

摘要翻译： 式（I-1）的顺式环氧化合物及其药学上可接受的盐，水合物和溶剂合物：其中：R1是环烷基或芳基取代的低级烷基; A是下式的官能化酰基：其中R 2是C 1-4烷基或酰胺取代的C 1-2烷基; R 3是C 1-4烷氧基，芳氧基烷基或芳基烷氧基或含氮芳族基团，或被含氮芳族基团取代的低级烷氧基或具有下式的基团：其中R 4是氢或 甲基，R 5为被含氮芳族基团取代的烷基; m为0或1; 并且B是式“IMAGE”的官能化氨基，其中R 8和R 9独立地是任选被芳族基团或芳族基团取代的C 1-4烷基。

公开(公告)号：US5696134A

公开(公告)日：1997-12-09

申请号：US473877

申请日：1995-06-07

申请人： Heungsik Yoon ,  Nakyen Choy ,  Sung Chun Kim ,  Ho Il Choi ,  Young Chan Son ,  Chi Hyo Park ,  Kwang-Yul Moon ,  Wonhee Jung ,  Chung Ryeol Kim ,  Chang Sun Lee ,  Jong Sung Koh ,  Sang Soo Kim

发明人： Heungsik Yoon ,  Nakyen Choy ,  Sung Chun Kim ,  Ho Il Choi ,  Young Chan Son ,  Chi Hyo Park ,  Kwang-Yul Moon ,  Wonhee Jung ,  Chung Ryeol Kim ,  Chang Sun Lee ,  Jong Sung Koh ,  Sang Soo Kim

IPC分类号： A61K38/00 ,  C07K5/02 ,  A61K31/44 ,  A61K31/47

CPC分类号： C07K5/0207 ,  A61K38/00

摘要： Novel cis-epoxide compounds of formula (I) are useful for treating or preventing diseases caused by HIV infection: ##STR1## wherein A, B, R.sub.1 to R.sub.4 and n have the same meanings as defined in the specification. The novel HIV protease inhibitor of the formula (I) has a specific structure to form a stable bonding with the enzyme active site, which entails a highly enhanced irreversible inhibition against HIV protease.

摘要翻译： 式（I）的新型顺式环氧化合物可用于治疗或预防由HIV感染引起的疾病：其中A，B，R 1至R 4和n具有与说明书中所定义相同的含义。 式（I）的新型HIV蛋白酶抑制剂具有与酶活性位点形成稳定结合的特定结构，这对HIV蛋白酶具有高度的不可逆抑制作用。

公开(公告)号：US5773468A

公开(公告)日：1998-06-30

申请号：US572402

申请日：1995-12-14

申请人： Sung Chun Kim ,  Young Chan Son ,  Ho Il Choi ,  Heungsik Yoon ,  Chi Hyo Park ,  Nakyen Choy ,  Chang Sun Lee ,  Jong Sung Koh ,  Kwang Yul Moon ,  Won Hee Jung ,  Chung Ryeol Kim

发明人： Sung Chun Kim ,  Young Chan Son ,  Ho Il Choi ,  Heungsik Yoon ,  Chi Hyo Park ,  Nakyen Choy ,  Chang Sun Lee ,  Jong Sung Koh ,  Kwang Yul Moon ,  Won Hee Jung ,  Chung Ryeol Kim

IPC分类号： A61K38/00 ,  C07D303/46 ,  A01N43/20 ,  A01N31/34

CPC分类号： C07D303/46 ,  A61K38/00

摘要： The present invention relates to a novel compound of formula (I) and pharmaceutically acceptable salts, hydrates and solvates thereof which is an irreversible HIV protease inhibitor; a process for the preparation thereof; and a pharmaceutical composition containing the compound as an active ingredient which is useful for treating or preventing diseases caused by HIV infection. ##STR1##

摘要翻译： 本发明涉及新的式（I）化合物及其药学上可接受的盐，水合物和溶剂化物，其是不可逆的HIV蛋白酶抑制剂; 其制备方法; 以及含有该化合物作为活性成分的药物组合物，其可用于治疗或预防由HIV感染引起的疾病。 （一）

公开(公告)号：US20060112724A1

公开(公告)日：2006-06-01

申请号：US11034779

申请日：2005-01-14

申请人： Seung Yong Chang ,  Yoon Been Lee ,  Sung Chun Kim ,  Se Dong Chang

发明人： Seung Yong Chang ,  Yoon Been Lee ,  Sung Chun Kim ,  Se Dong Chang

IPC分类号： F25B43/02

CPC分类号： F25B43/02 ,  B01D19/0057 ,  F25B2400/02 ,  F25B2500/01

摘要： Disclosed herein are an oil separator and a cooling-cycle apparatus using the oil separator. To a casing of the separator is connected an inflow tube to supply gaseous refrigerant and oil into the casing for allowing them flowing in a swirl pattern, thereby being separated from each other in a cyclone separation manner. Such a separation manner results in an improved oil separation efficiency.

摘要翻译： 本文公开了使用油分离器的油分离器和冷却循环装置。 分离器的壳体连接有流入管，以将气态制冷剂和油供应到壳体中，以使它们以旋转图案流动，从而以旋风分离方式彼此分离。 这种分离方式导致油分离效率的改善。

公开(公告)号：US06973796B2

公开(公告)日：2005-12-13

申请号：US10641143

申请日：2003-08-15

申请人： Jong Han Park ,  Young Min Park ,  Chang Seon Lee ,  Sung Oh Choi ,  Sung Chun Kim

发明人： Jong Han Park ,  Young Min Park ,  Chang Seon Lee ,  Sung Oh Choi ,  Sung Chun Kim

IPC分类号： F24F11/02 ,  F25B13/00 ,  F25B29/00 ,  F25B41/04 ,  F25B41/00 ,  F25B49/00

CPC分类号： F25B13/00 ,  F25B2313/007 ,  F25B2313/0231 ,  F25B2313/0315 ,  F25B2400/23

摘要： Disclosed is a multi-air conditioner including: an outdoor unit having a compressor, an outdoor heat exchanger, and an outdoor fan for ventilating the outdoor heat exchanger; a plurality of indoor units each having an electronic expansion valve and an indoor heat exchanger; a distributor for selectively guiding a refrigerant of the outdoor unit into the plurality of indoor units according to an operation condition; a four-way valve for selectively switching a flow direction of the refrigerant flowing through the outdoor heat exchanger; a selective expansion unit for selectively expanding the refrigerant according to the flow direction of the refrigerant; a gas-liquid separator for separating a vapor-phase refrigerant and a liquid-phase refrigerant, from the refrigerant flowing from the outdoor heat exchanger; and a connection tube part having a first connection tube for connecting the four-way valve with a distributor, a second connection tube for connecting an upper portion of the gas-liquid separator with the distributor thereby guiding a vapor-phase refrigerant, and a third connection tube for connecting a lower portion of the gas-liquid separator with the distributor thereby guiding a liquid-phase refrigerant.

摘要翻译： 本发明公开了一种多空调机，具备：室外机，具有压缩机，室外热交换器和室外热交换器的室外风扇; 多个室内机，各具有电子膨胀阀和室内热交换器; 分配器，用于根据操作条件选择性地将室外机的制冷剂引导到多个室内机中; 用于选择性地切换流过室外热交换器的制冷剂的流动方向的四通阀; 选择性膨胀单元，用于根据制冷剂的流动方向选择性地膨胀制冷剂; 用于从室外热交换器流出的制冷剂分离气相制冷剂和液相制冷剂的气液分离器; 以及连接管部，其具有用于将四通阀与分配器连接的第一连接管，用于将气液分离器的上部与分配器连接的第二连接管，从而引导气相制冷剂，以及第三连接管 连接管，用于将气液分离器的下部与分配器连接，从而引导液相制冷剂。

公开(公告)号：US06767184B2

公开(公告)日：2004-07-27

申请号：US10096588

申请日：2002-03-14

申请人： Sung Chun Kim ,  Young Min Park ,  Jong Han Park ,  Jun Sei Lee ,  Sung Oh Choi

发明人： Sung Chun Kim ,  Young Min Park ,  Jong Han Park ,  Jun Sei Lee ,  Sung Oh Choi

IPC分类号： F04D2942

CPC分类号： F04D29/422 ,  F04D29/4226

摘要： A blower having a turbo fan is installed in a scroll housing with a cutoff. The cutoff has an inclination angle of approximately 50 to 80°, so that it is possible to draw in an increased amount of air while reducing the flow resistance of air. Accordingly, blowing efficiency is improved while simultaneously reducing the generation of noise and vibration.

摘要翻译： 具有涡轮风扇的鼓风机安装在具有切断装置的涡旋壳体中。 截止具有大约50至80°的倾斜角度，使得可以在降低空气的流动阻力的同时吸入增加的空气量。 因此，提高吹风效率，同时减少噪音和振动的产生。

公开(公告)号：US06478538B2

公开(公告)日：2002-11-12

申请号：US09799606

申请日：2001-03-07

申请人： Sung Chun Kim

发明人： Sung Chun Kim

IPC分类号： F04D2940

CPC分类号： F04D29/4226

摘要： Turbo fan housing in a window type air conditioner including a flow guide including an inlet plate having a bell mouth for guiding room air, a base plate opposite to the inlet plate having an indoor fan mounted thereto for drawing the room air, and a separation wall between the inlet plate and the base plate to surround the turbo fan, an outlet formed by extension of the base plate and the separation wall from an opening formed on one side of the flow guide, and a cutoff formed on an inside of the separation wall connecting the outlet and the flow guide, wherein the indoor fan is a turbo fan, and a flow passage in the flow guide is formed to cause sharp flow direction changes, for converting a portion of dynamic pressure of the room air into a static pressure in the flow direction changes.

公开(公告)号：US07716941B2

公开(公告)日：2010-05-18

申请号：US11678974

申请日：2007-02-26

申请人： Jong Han Park ,  Young Min Park ,  Chang Seon Lee ,  Sung Oh Choi ,  Sung Chun Kim ,  Seung Yong Chang ,  Seok Ho Yoon ,  Baik Young Chung

发明人： Jong Han Park ,  Young Min Park ,  Chang Seon Lee ,  Sung Oh Choi ,  Sung Chun Kim ,  Seung Yong Chang ,  Seok Ho Yoon ,  Baik Young Chung

IPC分类号： F25B47/00

CPC分类号： F25B47/022 ,  F24F11/42 ,  F25B13/00 ,  F25B2313/007 ,  F25B2313/0231 ,  F25B2313/02331 ,  F25B2313/02334 ,  F25B2313/02532 ,  F25B2313/02542

摘要： Multi-type air conditioner comprising an outdoor unit installed in an outdoor, comprising a compressor, a refrigerant flow controlling part connected to a discharge end of the compressor for guiding the refrigerant proper to operation conditions selectively, an outdoor heat exchanger connected to the refrigerant flow controlling part, a defrosting device at a side of the outdoor heat exchanger, and a piping system connected between the parts, a plurality of indoor units each installed in a room and having an indoor heat exchanger and an electronic expansion valve having one end connected to one end of the indoor heat exchanger, and a distributor between the outdoor unit and the indoor units for selectively guiding refrigerant from the outdoor unit to the plurality of indoor units proper to operation conditions, and guiding the refrigerant passed through the indoor units to the outdoor unit again.

摘要翻译： 一种多室型空调机，包括安装在室外的室外机，包括压缩机，制冷剂流量控制部分，连接到压缩机的排出端，用于选择性地引导适合于运行状态的制冷剂，连接到制冷剂流的室外热交换器 室外热交换器一侧的除霜装置和连接在所述部件之间的管道系统，多个室内单元，每个室内单元安装在室内并具有室内热交换器和电子膨胀阀，所述电子膨胀阀的一端连接到 室内热交换器的一端和室外机与室内机之间的分配器，用于将制冷剂从室外机选择性地引导到适合于运行条件的多个室内机，并将通过室内机的制冷剂引导到室外 单位。

公开(公告)号：US07185502B2

公开(公告)日：2007-03-06

申请号：US10729013

申请日：2003-12-08

申请人： Jong Han Park ,  Young Min Park ,  Chang Seon Lee ,  Sung Oh Choi ,  Sung Chun Kim ,  Seung Yong Chang ,  Seok Ho Yoon ,  Baik Young Chung

发明人： Jong Han Park ,  Young Min Park ,  Chang Seon Lee ,  Sung Oh Choi ,  Sung Chun Kim ,  Seung Yong Chang ,  Seok Ho Yoon ,  Baik Young Chung

IPC分类号： F25D21/06 ,  F25B13/00 ,  F25B29/00 ,  F25B43/00

CPC分类号： F25B43/006 ,  F25B13/00 ,  F25B47/006 ,  F25B2313/023 ,  F25B2400/01

摘要： Air conditioner, and method for controlling an operation of the same, the air conditioner including a sheath heater in the accumulator for heating the refrigerant in room heating for delaying deposition of frost on the outdoor heat exchanger. The sheath heater includes a coil formed heat generating part, and two electrodes connected to the heat generating part for supplying power. The method including the step of varying the heat generating rate of the sheath heater with an exterior temperature or a capacity of the indoor unit, thereby delaying deposition of frost on the outdoor heat exchanger.

摘要翻译： 空调器及其操作方法，所述空调机包括在所述蓄热器中的护套加热器，用于在室内加热用于在室外热交换器上延迟霜冻的室内制冷剂。 鞘加热器包括线圈形成的发热部分，以及连接到用于供电的发热部分的两个电极。 该方法包括以外部温度或室内单元的容量改变护套加热器的发热速率的步骤，从而延迟霜冻在室外热交换器上。