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公开(公告)号:US20060234268A1
公开(公告)日:2006-10-19
申请号:US11379047
申请日:2006-04-17
申请人: Sungwhan An , Chiwang Yoon , Youngho Moon , Tae Oh , Dae Yoon , Myungsoon Kim
发明人: Sungwhan An , Chiwang Yoon , Youngho Moon , Tae Oh , Dae Yoon , Myungsoon Kim
CPC分类号: C12Q1/6844 , C12Q1/6853 , C12Q2531/101 , C12Q2527/107 , C12Q2525/113 , C12Q2525/173 , C12Q2525/161
摘要: The present application discloses a method for linear amplification of RNA.
摘要翻译: 本申请公开了一种用于线性扩增RNA的方法。
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公开(公告)号:US20060234254A1
公开(公告)日:2006-10-19
申请号:US11279894
申请日:2006-04-15
申请人: Sungwhan An , Chiwang Yoon , Youngho Moon , Tae Oh , Dae Yoon , Myungsoon Kim
发明人: Sungwhan An , Chiwang Yoon , Youngho Moon , Tae Oh , Dae Yoon , Myungsoon Kim
CPC分类号: C12Q1/6886 , C12Q1/6827 , C12Q2600/154 , C12Q2565/501 , C12Q2525/117
摘要: The present application discloses an epigenetic marker for colon cancer.
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公开(公告)号:US20070264659A1
公开(公告)日:2007-11-15
申请号:US11747754
申请日:2007-05-11
申请人: Sungwhan An , Chiwang Yoon , Youngho Moon , Tae Jeong Oh , Myungsoon Kim , Yeul Hong Kim
发明人: Sungwhan An , Chiwang Yoon , Youngho Moon , Tae Jeong Oh , Myungsoon Kim , Yeul Hong Kim
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6886 , C12Q2600/154
摘要: The present application discloses an epigenetic marker for lung cancer.
摘要翻译: 本申请公开了肺癌的表观遗传标记物。
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公开(公告)号:US20130071836A9
公开(公告)日:2013-03-21
申请号:US11279894
申请日:2006-04-15
申请人: Sungwhan An , Chiwang Yoon , Youngho Moon , Tae Jeong Oh , Dae Kyoung Yoon , Myungsoon Kim
发明人: Sungwhan An , Chiwang Yoon , Youngho Moon , Tae Jeong Oh , Dae Kyoung Yoon , Myungsoon Kim
CPC分类号: C12Q1/6886 , C12Q1/6827 , C12Q2600/154 , C12Q2565/501 , C12Q2525/117
摘要: The present application discloses an epigenetic marker for colon cancer.
摘要翻译: 本申请公开了一种结肠癌的表观遗传学标记物。
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公开(公告)号:US20070259368A1
公开(公告)日:2007-11-08
申请号:US11744198
申请日:2007-05-03
申请人: Sungwhan An , Chiwang Yoon , Youngho Moon , Tae Jeong Oh , Myungsoon Kim , Seung-Moo Noh
发明人: Sungwhan An , Chiwang Yoon , Youngho Moon , Tae Jeong Oh , Myungsoon Kim , Seung-Moo Noh
CPC分类号: C12Q1/6886 , C12Q2600/154
摘要: The present application discloses an epigenetic marker for gastric cancer.
摘要翻译: 本申请公开了胃癌的表观遗传标记物。
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公开(公告)号:US20060211009A1
公开(公告)日:2006-09-21
申请号:US11277033
申请日:2006-03-20
申请人: Sungwhan An , Chiwang Yoon , Tae Oh , Myungsoon Kim
发明人: Sungwhan An , Chiwang Yoon , Tae Oh , Myungsoon Kim
CPC分类号: C12Q1/6886 , C12Q2600/112 , C12Q2600/154
摘要: The present application discloses a method for discovering a methylation marker gene for the conversion of a cell comprising: (i) comparing converted and unconverted cell gene expression content to identify a gene that is present in greater abundance in the unconverted cell; (ii) treating a converted cell with a demethylating agent and comparing its gene expression content with gene expression content of an untreated converted cell to identify a gene that is present in greater abundance in the cell treated with the demethylating agent; and (iii) identifying a gene that is common to the identified genes in steps (i) and (ii), wherein the common identified gene is the methylation marker gene.
摘要翻译: 本申请公开了一种用于发现用于转化细胞的甲基化标记基因的方法,包括:(i)比较转化和未转化的细胞基因表达含量,以鉴定未转化细胞中更丰富的基因; (ii)用去甲基化剂处理转化的细胞,并将其基因表达含量与未处理的转化细胞的基因表达含量进行比较,以鉴定在用去甲基化试剂处理的细胞中更丰富的基因; 和(iii)鉴定步骤(i)和(ii)中所鉴定的基因共有的基因,其中常见的鉴定基因是甲基化标记基因。
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