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公开(公告)号:US20220185799A1
公开(公告)日:2022-06-16
申请号:US17452786
申请日:2021-10-29
Applicant: Sunovion Pharmaceuticals Inc. , PGI Drug Discovery LLC
Inventor: Linghong XIE , Philip Glyn JONES , Kerry L. SPEAR , Noel Aaron POWELL , Taleen G. HANANIA , Vadim ALEXANDROV
IPC: C07D405/04 , C07D405/14 , C07D413/14 , C07D493/04 , C07D413/04
Abstract: Disclosed are compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, Ra, R1, R2, R3, R4, R6, w and n1 are defined and described herein; compositions thereof; and methods of use thereof. These compounds are useful for treating a variety of neurological and psychiatric disorders, such as those described herein.
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2.
公开(公告)号:US20200024286A1
公开(公告)日:2020-01-23
申请号:US16403734
申请日:2019-05-06
Applicant: Sunovion Pharmaceuticals Inc. , PGI Drug Discovery LLC
Inventor: Milan CHYTIL , Sharon ENGEL , Taleen G. HANANIA , Vadim ALEXANDROV , Emer LEAHY
IPC: C07D498/04 , C07D231/56 , C07D498/20 , C07D498/14 , C07D498/22
Abstract: Disclosed are compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein Ring B, A1, A2, R6, w and n1 are defined and described herein; compositions thereof; and methods of use thereof. These compounds are useful for treating a variety of neurological and psychiatric disorders, such as those described herein.
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3.
公开(公告)号:US20180057506A1
公开(公告)日:2018-03-01
申请号:US15666719
申请日:2017-08-02
Applicant: Sunovion Pharmaceuticals Inc. , PGI Drug Discovery LLC
Inventor: Milan CHYTIL , Sharon Engel , Taleen G. HANANIA , Vadim ALEXANDROV , Emer LEAHY
IPC: C07D498/04 , C07D498/22 , C07D498/14 , C07D498/20
CPC classification number: C07D498/04 , C07D231/56 , C07D498/14 , C07D498/20 , C07D498/22
Abstract: Disclosed are compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein Ring B, A1, A2, R6, w and n1 are defined and described herein; compositions thereof; and methods of use thereof. These compounds are useful for treating a variety of neurological and psychiatric disorders, such as those described herein.
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4.
公开(公告)号:US20210300942A1
公开(公告)日:2021-09-30
申请号:US17179477
申请日:2021-02-19
Applicant: Sunovion Pharmaceuticals Inc. , PGI Drug Discovery LLC
Inventor: Milan CHYTIL , Sharon ENGEL , Taleen G. HANANIA , Vadim ALEXANDROV , Emer LEAHY
IPC: C07D498/04 , C07D231/56 , C07D498/20 , C07D498/14 , C07D498/22
Abstract: Disclosed are compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein Ring B, A1, A2, R6, w and n1 are defined and described herein; compositions thereof; and methods of use thereof. These compounds are useful for treating a variety of neurological and psychiatric disorders, such as those described herein.
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公开(公告)号:US20190389845A1
公开(公告)日:2019-12-26
申请号:US16403698
申请日:2019-05-06
Applicant: Sunovion Pharmaceuticals Inc. , PGI Drug Discovery LLC
Inventor: Linghong Xie , Philip Glyn JONES , Kerry L. SPEAR , Noel Aaron POWELL , Taleen G. HANANIA , Vadim ALEXANDROV
IPC: C07D405/04 , C07D405/14 , C07D413/14 , C07D493/04 , C07D413/04
Abstract: Disclosed are compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, Ra, R1, R2, R3, R4, R6, w and n1 are defined and described herein; compositions thereof; and methods of use thereof. These compounds are useful for treating a variety of neurological and psychiatric disorders, such as those described herein.
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公开(公告)号:US20180028492A1
公开(公告)日:2018-02-01
申请号:US15663672
申请日:2017-07-28
Applicant: Sunovion Pharmaceuticals Inc.
Inventor: Noel Aaron POWELL , Taleen G. HANANIA , Vadim ALEXANDROV , Carrie A. BOWEN
IPC: A61K31/353 , A61K45/06 , C07D311/76 , C07D313/08 , A61K31/13 , C12P17/06
CPC classification number: A61K31/353 , A61K31/13 , A61K31/352 , A61K45/06 , C07D311/76 , C07D313/08 , C12P17/06
Abstract: Compounds of formula I: are disclosed, as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric diseases and disorders in a subject in need thereof are also disclosed.
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