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    Biodegradable and resorbable surgical material and process for preparation of the same
    1.
    发明授权
    Biodegradable and resorbable surgical material and process for preparation of the same 失效
    可生物降解和可吸收的手术材料及其制备方法

    公开(公告)号：US5227412A

    公开(公告)日：1993-07-13

    申请号：US944019

    申请日：1992-09-14

    申请人： Suong-Hyu Hyon ,  Yoshito Ikada ,  Yasuo Shikinami ,  Kaoru Tsuta ,  Hidekazu Boutani

    发明人： Suong-Hyu Hyon ,  Yoshito Ikada ,  Yasuo Shikinami ,  Kaoru Tsuta ,  Hidekazu Boutani

    IPC分类号： A61L31/06 ,  A61L31/14

    CPC分类号： A61L31/148 ,  A61L31/06 ,  A61L31/14

    摘要： Biodegradable and resorbable surgical materials of molded articles of poly(lactic acid) or copolymers of lactic acid and glycolic acid, characterized in that the articles are molecular-orientated, and having a bending strength of 1.6.times.10.sup.33 to 2.5.times.10.sup.3 kg/cm.sup.2, a bending modulus of 5.5.times.10.sup.2 to 24.0.times.10.sup.2 kg/cm.sup.2, a crystallinity, determined by density measurement, of 10 to 60%, and a viscosity average molecular weight measured after melt processing of not less than 200,000, and in that at least 80% of initial strength of the articles is maintained after dipping in a saline at 37.degree. C. for three months.

    摘要翻译： 聚（乳酸）或乳酸和乙醇酸共聚物的可生物降解和可再吸收的外科材料，其特征在于制品是分子取向的，并且具有1.6×1033至2.5×10 3 kg / cm 2的弯曲强度， 5.5×102〜24.0×102kg / cm2的模量，通过密度测定确定的结晶度为10〜60％，熔融加工后测定的粘均分子量为20万以上，初始值为80％以上 在37℃的盐水中浸渍3个月后，保持制品的强度。

    Cosmetic path using method thereof, and cosmetic path package
    4.
    发明申请
    Cosmetic path using method thereof, and cosmetic path package 审中-公开
    化妆品路径及其美容路径包装

    公开(公告)号：US20070098770A1

    公开(公告)日：2007-05-03

    申请号：US10559465

    申请日：2004-06-03

    申请人： Yasuo Shikinami ,  Kaoru Tsuta ,  Kazuhiro Yasukawa ,  Kenshi Okazaki ,  Hiroshi Morii

    发明人： Yasuo Shikinami ,  Kaoru Tsuta ,  Kazuhiro Yasukawa ,  Kenshi Okazaki ,  Hiroshi Morii

    IPC分类号： A61K9/70

    CPC分类号： A61K8/676 ,  A61K8/0208 ,  A61K8/87 ,  A61Q19/00

    摘要： The present invention provides a cosmetic patch which can contain therein either one of a water soluble vitamin and a fat soluble vitamin, particularly when the vitamin is vitamin C, can contain and retain vitamin C stably while avoiding its deterioration due to oxidation or hydrolysis and not causing deterioration of the gel, and is equipped with a desired level of adhesive force; a using method of a cosmetic patch capable of effectively transferring vitamin C into the skin from the cosmetic patch; and a cosmetic patch package for storing the cosmetic patch therein. The present invention relates to a cosmetic patch obtained by incorporating a vitamin in an adhesive polyurethane gel which has hydrophilic alkylene oxide segments and hydrophobic alkylene oxide segments and has most or all of these segments in liquid form at normal temperature.

    摘要翻译： 本发明提供一种化妆品贴片，其中可以含有水溶性维生素和脂溶性维生素之一，特别是当维生素是维生素C时，可以稳定地含有并保持维生素C，同时避免其由于氧化或水解引起的变质，而不是 导致凝胶变质，并具有期望的粘合力水平; 一种化妆品贴片的使用方法，其能够从化妆品贴片有效地将维生素C转移到皮肤中; 以及用于在其中存储化妆品贴片的化妆品贴片包装。 本发明涉及通过将维生素掺入粘着性聚氨酯凝胶而得到的化妆品贴剂，该粘合剂聚氨酯凝胶具有亲水性环氧烷链段和疏水性烯化氧链段，并且这些链段中的大部分或全部在常温下为液态。

    GEL FOR ULTRASONIC PHANTOM
    5.
    发明申请
    GEL FOR ULTRASONIC PHANTOM 审中-公开
    超声波凝胶

    公开(公告)号：US20090286216A1

    公开(公告)日：2009-11-19

    申请号：US12095148

    申请日：2006-11-22

    申请人： Yasuo Shikinami ,  Kaoru Tsuta

    发明人： Yasuo Shikinami ,  Kaoru Tsuta

    IPC分类号： G09B23/28

    CPC分类号： A61B8/00 ,  A61B8/587 ,  G09B23/285

    摘要： A gel for an ultrasonic phantom is provided which has satisfactory ultrasonic characteristics, does not fluctuate in ultrasonic characteristics over long, and is free from germ multiplication, alteration, putrefaction, etc.The gel is a gel for ultrasonic phantoms which comprises: a segmented polyurethane gel having alkylene oxide segments which are mostly or wholly liquid at ordinary temperature; and a nonvolatile organic gel-swelling medium not participating in a urethane-forming reaction, the medium being contained in the segmented polyurethane gel. Due to the nonvolatile organic gel-swelling medium, the liquid segments and the like are kept in an extended state and the distance between the segments is increased. The gel hence has satisfactory ultrasonic characteristics concerning ultrasonic attenuation rate, propagation velocity, etc. The gel does not change in swelling-medium content with time and hence retains the satisfactory ultrasonic characteristics over long. Furthermore, the gel is free from germ multiplication, alteration, putrefaction, etc. because of the organic gel-swelling medium contained therein.

    摘要翻译： 提供了一种超声波体模凝胶，其超声波特性令人满意，超声波特性长时间不波动，无细菌增殖，改变，腐败等。凝胶是超声波模型的凝胶，包括：分段聚氨酯 凝胶具有在常温下大部分或全部为液体的环氧烷段; 和不参与氨基甲酸酯形成反应的非挥发性有机凝胶溶胀介质，所述介质包含在所述分段聚氨酯凝胶中。 由于非挥发性有机凝胶溶胀介质，液体段等保持在延伸状态，并且段之间的距离增加。 因此，凝胶具有超声波衰减率，传播速度等的令人满意的超声波特性。凝胶在溶胀介质含量随时间不变化，因此长时间保持令人满意的超声波特性。 此外，由于其中含有有机凝胶溶胀介质，凝胶不含细菌繁殖，改变，腐败等。

    Artificial-Intervertebral-Disk Insertion Jigs, Jig Set, And Artificial Intervertebral Disk
    6.
    发明申请
    Artificial-Intervertebral-Disk Insertion Jigs, Jig Set, And Artificial Intervertebral Disk 审中-公开
    人造椎间盘插入夹具，夹具和人造椎间盘

    公开(公告)号：US20080103596A1

    公开(公告)日：2008-05-01

    申请号：US11661444

    申请日：2004-12-28

    申请人： Yasuo Shikinami ,  Kaoru Tsuta ,  Yasuhiro Kawabe

    发明人： Yasuo Shikinami ,  Kaoru Tsuta ,  Yasuhiro Kawabe

    IPC分类号： A61F2/44

    CPC分类号： A61L27/00 ,  A61F2/442 ,  A61F2/4611 ,  A61F2002/30062 ,  A61F2002/30131 ,  A61F2002/30133 ,  A61F2002/30387 ,  A61F2002/304 ,  A61F2002/30461 ,  A61F2002/30471 ,  A61F2002/30563 ,  A61F2002/30594 ,  A61F2002/30617 ,  A61F2002/3068 ,  A61F2002/30785 ,  A61F2002/30795 ,  A61F2002/30841 ,  A61F2002/448 ,  A61F2002/4495 ,  A61F2002/4627 ,  A61F2210/0004 ,  A61F2220/0025 ,  A61F2220/0075 ,  A61F2220/0091 ,  A61F2230/0013 ,  A61F2230/0015 ,  A61F2250/0068 ,  A61F2250/0097 ,  A61F2310/00179

    摘要： Subjects are to provide a stand-alone artificial intervertebral disk which has flexible, nearly ideal, mechanical deformation properties and durability and is capable of being bonded and fixed to vertebral bodies at a high force and to provide an artificial-intervertebral-disk insertion jig with which the artificial intervertebral disk can be easily inserted and disposed between vertebrae without fail.The artificial intervertebral disk has a constitution comprising: a core material comprising a structure which is either a multiaxis three-dimensional woven structure or knit structure made of organic fibers arranged along three or more axes or a structure comprising a combination of the woven structure and the knit structure; and plates superposed respectively on the upper and lower sides of the core material, the plates being made of a biodegradable and bioabsorbable polymer containing bioactive bioceramic particles. Preferably, the plates have many perforations formed therein or the plates are ones in which the perforations are filled with a biodegradable and bioabsorbable material having bone conductivity and/or bone inductivity and having a high degradation rate. The insertion jig has a constitution comprising an upper jig and a lower jig, as a pair of jigs, which have been fitted to each other so as not to separate from each other in vertical directions and as to be capable of sliding against each other in back-and-forth directions, the upper jig and the lower jig having an upper holding part and a lower holding part which serve to hold an artificial intervertebral disk and have been formed as front parts of the upper jig and lower jig.

    摘要翻译： 受试者提供一种独立的人造椎间盘，其具有柔性，几乎理想的机械变形性能和耐久性，并且能够以高力粘合并固定在椎体上，并提供人造椎间盘插入夹具 其中人造椎间盘可以容易地插入和放置在椎骨之间，而不会失败。 人造椎间盘具有以下结构：芯材，其包含结构体，所述结构体是多轴立体编织结构或由沿三轴以上排列的有机纤维制成的针织结构，或包含所述织造结构和 针织结构; 和分别叠置在芯材的上侧和下侧的板，该板由包含生物活性生物陶瓷颗粒的可生物降解和生物可吸收的聚合物制成。 优选地，板在其中形成许多穿孔，或者板是其中穿孔填充有具有骨导电性和/或骨电感并且具有高降解速率的可生物降解和生物可吸收材料的板。 插入夹具具有上部夹具和下部夹具的构造，作为一对夹具，它们彼此嵌合，以便在垂直方向上彼此不分离并且能够相互滑动 上夹具和下夹具具有用于保持人造椎间盘的上保持部和下保持部，并且已经形成为上夹具和下夹具的前部。