公开(公告)号：US09993441B2

公开(公告)日：2018-06-12

申请号：US14669571

申请日：2015-03-26

Applicant: SurModics, Inc.

Inventor： Joseph Schmidt McGonigle ,  Aleksey V. Kurdyumov ,  Jeffrey J. Missling ,  Nathan A. Lockwood ,  Kevin W. Burton ,  Beth A. Petersen

IPC: A61F2/00 ,  A61K9/70 ,  A61K31/573 ,  A61K9/00 ,  A61K47/34 ,  A61L29/06 ,  A61L29/14 ,  A61L29/16 ,  A61L31/04 ,  A61F2/07 ,  A61F2/82 ,  A61L31/10

CPC classification number: A61K9/7007 ,  A61F2/07 ,  A61F2/82 ,  A61K9/0024 ,  A61K31/573 ,  A61K47/34 ,  A61L29/06 ,  A61L29/14 ,  A61L29/16 ,  A61L31/04 ,  A61L31/10 ,  A61L2300/404 ,  A61L2300/406 ,  C08L67/04

Abstract: A biocompatible polymeric controlled release matrix barrier structure for delivery of one or more bioactive agents from an implantable medical device is described. In an embodiment, a biocompatible polymeric controlled release matrix barrier structure is included. The biocompatible polymeric controlled release matrix can include a body structure formed of a compliant material comprising one or more compliant biocompatible polymers and one or more bioactive agents. The body structure can define a central aperture through which a subcutaneous element of an implantable medical device passes. Other embodiments are included herein.

公开(公告)号：US20160082110A1

公开(公告)日：2016-03-24

申请号：US14955528

申请日：2015-12-01

Applicant: SurModics, Inc.

Inventor： Kevin W. Burton ,  Howard Bowman ,  Danielle Biggs ,  Peter Markland

IPC: A61K47/34 ,  A61M5/19 ,  A61K9/00

CPC classification number: A61K47/34 ,  A61K9/0019 ,  A61K31/56 ,  A61L27/34 ,  A61L27/54 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/622 ,  A61M5/19 ,  A61N1/375 ,  A61N1/3968 ,  C08L67/04

Abstract: Described herein are terpolymer compositions, kits comprising the compositions, implant devices comprising the compositions, and methods of making and using same, including point of use methods.

Abstract translation: 本文描述的是三元共聚物组合物，包含该组合物的试剂盒，包含该组合物的植入装置及其制备和使用方法，包括使用方法。

公开(公告)号：US20150196497A1

公开(公告)日：2015-07-16

申请号：US14669571

申请日：2015-03-26

Applicant: SurModics, Inc.

Inventor： Joseph Schmidt McGonigle ,  Aleksey V. Kurdyumov ,  Jeffrey J. Missling ,  Nathan A. Lockwood ,  Kevin W. Burton ,  Beth A. Petersen

IPC: A61K9/70 ,  A61K31/573

CPC classification number: A61K9/7007 ,  A61F2/07 ,  A61F2/82 ,  A61K9/0024 ,  A61K31/573 ,  A61K47/34 ,  A61L29/06 ,  A61L29/14 ,  A61L29/16 ,  A61L31/04 ,  A61L31/10 ,  A61L2300/404 ,  A61L2300/406 ,  C08L67/04

Abstract: A biocompatible polymeric controlled release matrix barrier structure for delivery of one or more bioactive agents from an implantable medical device is described. In an embodiment, a biocompatible polymeric controlled release matrix barrier structure is included. The biocompatible polymeric controlled release matrix can include a body structure formed of a compliant material comprising one or more compliant biocompatible polymers and one or more bioactive agents. The body structure can define a central aperture through which a subcutaneous element of an implantable medical device passes. Other embodiments are included herein.

Abstract translation: 描述了用于从可植入医疗装置递送一种或多种生物活性剂的生物相容性聚合物控制释放基质屏障结构。 在一个实施方案中，包括生物相容性聚合物控制释放基质屏障结构。 生物相容性聚合物控制释放基质可以包括由包含一种或多种顺应性生物相容性聚合物和一种或多种生物活性剂的柔顺材料形成的体结构。 身体结构可以限定可植入医疗装置的皮下元件通过的中心孔。 本文还包括其它实施例。