-
公开(公告)号:US20050136061A1
公开(公告)日:2005-06-23
申请号:US11018102
申请日:2004-12-21
申请人: Susan Dillon , Alfred Del Vecchio , Chichi Huang , Karyn O'Neil , Robert Sarisky
发明人: Susan Dillon , Alfred Del Vecchio , Chichi Huang , Karyn O'Neil , Robert Sarisky
CPC分类号: C07K14/005 , C07K16/00 , C07K2317/52 , C07K2317/56 , C07K2319/00 , C07K2319/035 , C07K2319/31 , C07K2319/74 , C12N2740/16122 , C12N2740/16222
摘要: HIV gp4l mimetibody polypeptides and encoding polynucleotides are disclosed. Methods of utilizing the polypeptides to reduce or inhibit HIV fusion with a cell membrane and entry into target cells are also disclosed.
摘要翻译: 公开了HIV gp4l模拟体多肽和编码多核苷酸。 还公开了利用多肽来减少或抑制与细胞膜的HIV融合并进入靶细胞的方法。
-
公开(公告)号:US20130280263A1
公开(公告)日:2013-10-24
申请号:US13798494
申请日:2013-03-13
申请人: Mark Cunningham , Yiqing Feng , Katharine Heeringa , Jinquan Luo , Robert Rauchenberger , Mark Rutz , Lani San Mateo , Robert Sarisky , Raymond Sweet , Fang Teng , Alexey Teplyakov , Sheng-Jiun Wu
发明人: Mark Cunningham , Yiqing Feng , Katharine Heeringa , Jinquan Luo , Robert Rauchenberger , Mark Rutz , Lani San Mateo , Robert Sarisky , Raymond Sweet , Fang Teng , Alexey Teplyakov , Sheng-Jiun Wu
IPC分类号: C07K16/28
CPC分类号: C07K16/2896 , A61K39/39533 , A61K39/3955 , A61K2039/505 , C07H21/04 , C07K14/705 , C07K16/18 , C07K16/28 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2317/94 , C12N5/10 , C12N5/12 , C12N15/117 , C12N15/63 , C12N2310/17 , A61K39/00 , A61K2300/00
摘要: Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
-
公开(公告)号:US20110008352A1
公开(公告)日:2011-01-13
申请号:US12770147
申请日:2010-04-29
申请人: Mark Cunningham , Yiqing Feng , Katharine Heeringa , Jinquan Luo , Robert Rauchenberger , Mark Rutz , Lani San Mateo , Robert Sarisky , Raymond Sweet , Fang Teng , Alexey Teplyakov , Sheng-Jiun Wu
发明人: Mark Cunningham , Yiqing Feng , Katharine Heeringa , Jinquan Luo , Robert Rauchenberger , Mark Rutz , Lani San Mateo , Robert Sarisky , Raymond Sweet , Fang Teng , Alexey Teplyakov , Sheng-Jiun Wu
IPC分类号: A61K39/395 , C07K16/28 , A61P29/00 , A61P19/02 , A61P37/02 , A61P11/06 , A61P11/00 , A61P31/12 , A61P31/16 , A61P1/04 , A61P3/10 , A61P3/00
CPC分类号: C07K16/2896 , A61K39/39533 , A61K39/3955 , A61K2039/505 , C07H21/04 , C07K14/705 , C07K16/18 , C07K16/28 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2317/94 , C12N5/10 , C12N5/12 , C12N15/117 , C12N15/63 , C12N2310/17 , A61K39/00 , A61K2300/00
摘要: Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
摘要翻译: 公开了Toll样受体3(TLR3)抗体拮抗剂,编码TLR3抗体拮抗剂或其片段的多核苷酸,以及制备和使用前述物质的方法。
-
公开(公告)号:US20140212426A1
公开(公告)日:2014-07-31
申请号:US13751718
申请日:2013-01-28
申请人: Mark Cunningham , Yiqing Feng , Katharine Heeringa , Jinquan Luo , Robert Rauchenberger , Mark Rutz , Lani San Mateo , Robert Sarisky , Vedrana Stojanovic-Susulic , Raymond Sweet , Fang Teng , Alexey Teplyakov , Sheng-Jiun Wu
发明人: Mark Cunningham , Yiqing Feng , Katharine Heeringa , Jinquan Luo , Robert Rauchenberger , Mark Rutz , Lani San Mateo , Robert Sarisky , Vedrana Stojanovic-Susulic , Raymond Sweet , Fang Teng , Alexey Teplyakov , Sheng-Jiun Wu
IPC分类号: C07K16/28
CPC分类号: C07K16/2896 , A61K39/39533 , A61K39/3955 , A61K2039/505 , C07H21/04 , C07K14/705 , C07K16/18 , C07K16/28 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2317/94 , C12N5/10 , C12N5/12 , C12N15/117 , C12N15/63 , C12N2310/17 , A61K39/00 , A61K2300/00
摘要: Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
摘要翻译: 公开了Toll样受体3(TLR3)抗体拮抗剂,编码TLR3抗体拮抗剂或其片段的多核苷酸,以及制备和使用前述物质的方法。
-
5.Toll-Like Receptor 3 Antagonists for the Treatment of Metabolic and Cardiovascular Diseases 审中-公开
标题翻译: Toll样受体3治疗代谢和心血管疾病的拮抗剂公开(公告)号:US20130090457A1
公开(公告)日:2013-04-11
申请号:US13628434
申请日:2012-09-27
申请人: Mark Cunningham , Yiqing Feng , Katharine Heeringa , Jinquan Luo , Robert Rauchenberger , Mark Rutz , Lani San Mateo , Robert Sarisky , Vedrana Stojanovic-Susulic , Raymond Sweet , Fang Teng , Alexey Teplyakov , Linda Wu , Sheng-Jiun Wu , Eilyn Lacy
发明人: Mark Cunningham , Yiqing Feng , Katharine Heeringa , Jinquan Luo , Robert Rauchenberger , Mark Rutz , Lani San Mateo , Robert Sarisky , Vedrana Stojanovic-Susulic , Raymond Sweet , Fang Teng , Alexey Teplyakov , Linda Wu , Sheng-Jiun Wu , Eilyn Lacy
IPC分类号: C07K16/28
CPC分类号: C07K16/2896 , A61K2039/505 , C07K16/28 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要: Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
摘要翻译: 公开了Toll样受体3(TLR3)抗体拮抗剂,编码TLR3抗体拮抗剂或其片段的多核苷酸,以及制备和使用前述物质的方法。
-
公开(公告)号:US20070098716A1
公开(公告)日:2007-05-03
申请号:US11553633
申请日:2006-10-27
申请人: Karen Duffy , Chong Huang , Roberta Lamb , Mouhamadou Mbow , Robert Sarisky , Lani San Mateo
发明人: Karen Duffy , Chong Huang , Roberta Lamb , Mouhamadou Mbow , Robert Sarisky , Lani San Mateo
IPC分类号: A61K39/395 , C07H21/04 , C12P21/06 , C12N5/06 , C07K16/28
CPC分类号: C07K16/2896 , A61K2039/505 , C07K2317/56 , C07K2317/567 , C07K2317/75
摘要: Toll Like Receptor 3 (TLR3) modulators, such as antibodies, polynucleotides encoding TLR3 antibodies or fragments thereof, and methods of making and using the foregoing are disclosed.
摘要翻译: 公开了Toll样受体3(TLR3)调节剂,例如抗体,编码TLR3抗体的多核苷酸或其片段,以及制备和使用前述物质的方法。
-
7.Toll-Like Receptor 3 Antagonists for the Treatment of Metabolic and Cardiovascular Diseases 审中-公开
标题翻译: Toll样受体3治疗代谢和心血管疾病的拮抗剂公开(公告)号:US20140017250A1
公开(公告)日:2014-01-16
申请号:US13887797
申请日:2013-05-06
申请人: Mark Cunningham , Yiqing Feng , Katharine Heeringa , Jinquan Luo , Robert Rauchenberger , Mark Rutz , Lani San Mateo , Robert Sarisky , Vedrana Stojanovic-Susulic , Raymond Sweet , Fang Teng , Alexey Teplyakov , Linda Wu , Sheng-Jiun Wu , Eilyn Lacy
发明人: Mark Cunningham , Yiqing Feng , Katharine Heeringa , Jinquan Luo , Robert Rauchenberger , Mark Rutz , Lani San Mateo , Robert Sarisky , Vedrana Stojanovic-Susulic , Raymond Sweet , Fang Teng , Alexey Teplyakov , Linda Wu , Sheng-Jiun Wu , Eilyn Lacy
IPC分类号: C07K16/28
CPC分类号: C07K16/2896 , C07K16/28 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/76
摘要: Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
摘要翻译: 公开了Toll样受体3(TLR3)抗体拮抗剂,编码TLR3抗体拮抗剂或其片段的多核苷酸,以及制备和使用前述物质的方法。
-
公开(公告)号:US20070203064A1
公开(公告)日:2007-08-30
申请号:US11554253
申请日:2006-10-30
申请人: Karen Duffy , Mark Cunningham , M. Mbow , Robert Sarisky
发明人: Karen Duffy , Mark Cunningham , M. Mbow , Robert Sarisky
IPC分类号: A61K38/17 , A61K48/00 , C07K14/705
CPC分类号: C07K14/705 , A61K38/00 , A61K48/00
摘要: TLR3 glycosylation site muteins, nucleic acids encoding the muteins, and methods of modulating TLR3 activity in a cell are disclosed.
摘要翻译: 公开了TLR3糖基化位点突变蛋白,编码突变蛋白的核酸和调节细胞中TLR3活性的方法。
-
公开(公告)号:US20060115475A1
公开(公告)日:2006-06-01
申请号:US11291140
申请日:2005-11-30
申请人: Jill Carton , Shizhong Chen , Mark Cunningham , Anuk Das , Karen Duffy , Jill Giles-Komar , Theresa Goletz , David Knight , Roberta Lamb , Mouhamadou Mbow , Kristen Picha , Gopalan Raghunathan , Lani San Mateo , Robert Sarisky , Vedrana Stojanovic-Susulic , Nicole Stowell , Raymond Sweet , Shanrong Zhao
发明人: Jill Carton , Shizhong Chen , Mark Cunningham , Anuk Das , Karen Duffy , Jill Giles-Komar , Theresa Goletz , David Knight , Roberta Lamb , Mouhamadou Mbow , Kristen Picha , Gopalan Raghunathan , Lani San Mateo , Robert Sarisky , Vedrana Stojanovic-Susulic , Nicole Stowell , Raymond Sweet , Shanrong Zhao
IPC分类号: A61K39/395 , C07K16/28
CPC分类号: C07K16/2896 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92
摘要: Toll Like Receptor 3 (TLR3) antagonists, polynucleotides encoding TLR3 antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
摘要翻译: Toll样受体3(TLR3)拮抗剂,编码TLR3拮抗剂或其片段的多核苷酸,以及制备和使用前述物质的方法。
-
10.Method of treating asthma or reducing inflammatory cell lung inflammation by administering toll-like receptor 3 antibodies 有权
标题翻译: 通过施用toll样受体3抗体治疗哮喘或减少炎性细胞肺炎症的方法公开(公告)号:US09238693B2
公开(公告)日:2016-01-19
申请号:US13798494
申请日:2013-03-13
申请人: Mark Cunningham , Yiqing Feng , Katharine Heeringa , Jinquan Luo , Robert Rauchenberger , Mark Rutz , Lani San Mateo , Robert Sarisky , Raymond Sweet , Fang Teng , Alexey Teplyakov , Sheng-Jiun Wu
发明人: Mark Cunningham , Yiqing Feng , Katharine Heeringa , Jinquan Luo , Robert Rauchenberger , Mark Rutz , Lani San Mateo , Robert Sarisky , Raymond Sweet , Fang Teng , Alexey Teplyakov , Sheng-Jiun Wu
IPC分类号: A61K39/00 , A61K39/395 , C07K16/28 , C07H21/04 , C12N15/117 , C07K16/00 , C07K16/18 , C07K14/435 , C07K14/705 , C07K14/71 , C12N5/10 , C12N5/12 , C12N15/63
CPC分类号: C07K16/2896 , A61K39/39533 , A61K39/3955 , A61K2039/505 , C07H21/04 , C07K14/705 , C07K16/18 , C07K16/28 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2317/94 , C12N5/10 , C12N5/12 , C12N15/117 , C12N15/63 , C12N2310/17 , A61K39/00 , A61K2300/00
摘要: Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
摘要翻译: 公开了Toll样受体3(TLR3)抗体拮抗剂,编码TLR3抗体拮抗剂或其片段的多核苷酸,以及制备和使用前述物质的方法。
-
-
-
-
-
-
-
-
-