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1.发明授权公开(公告)号：US09163226B2
公开(公告)日：2015-10-20
申请号：US13422260
申请日：2012-03-16
申请人： Susanne Wieland , Petra Siegert , Astrid Spitz , Karl-Heinz Maurer , Timothy O'Connell , Inken Prueser , Marc-Steffen Schiedel , Thomas Eiting , Dorota Sendor-Mueller , Thorsten Bastigkeit , Konstantin Benda , Sven Mueller
发明人： Susanne Wieland , Petra Siegert , Astrid Spitz , Karl-Heinz Maurer , Timothy O'Connell , Inken Prueser , Marc-Steffen Schiedel , Thomas Eiting , Dorota Sendor-Mueller , Thorsten Bastigkeit , Konstantin Benda , Sven Mueller
IPC分类号： C12Q1/37 , C12N9/50 , D06M16/00 , C11D3/00 , C11D9/50 , C07H21/04 , C12N9/54 , C11D3/36 , C11D7/36 , C11D3/386
CPC分类号： C12N9/54 , C11D3/361 , C11D3/38618 , C11D7/36
摘要： Phosphonate-containing liquid washing or cleaning agent exhibiting advantageous proteolytic activity and improved storage stability comprising a protease having an amino acid sequence which is at least 80% identical to the amino acid sequence stated in SEQ ID NO. 1 and which comprises in position 99 in the numbering according to SEQ ID NO. 1 the amino acid glutamic acid (E) or aspartic acid (D) or the amino acid asparagine (N) or glutamine (Q) or the amino acid alanine (A) or glycine (G) or serine (S).
摘要翻译： 含有膦酸盐的液体洗涤剂或洗涤剂显示出有利的蛋白水解活性和改善的储存稳定性，其包含具有与SEQ ID NO：1所示氨基酸序列至少80％相同的氨基酸序列的蛋白酶。 1，并且其包含在根据SEQ ID NO：1的编号中的位置99。 氨基酸谷氨酸（E）或天冬氨酸（D）或氨基酸天冬酰胺（N）或谷氨酰胺（Q）或氨基酸丙氨酸（A）或甘氨酸（G）或丝氨酸（S）。
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公开(公告)号：US20130005637A1
公开(公告)日：2013-01-03
申请号：US13583602
申请日：2011-03-10
申请人： Petra Siegert , Ulrich Schwaneberg , Ronny Martinez , Marion Merkel , Astrid Spitz , Susanne Wieland , Hendrik Hellmuth , Karl-Heinz Maurer
发明人： Petra Siegert , Ulrich Schwaneberg , Ronny Martinez , Marion Merkel , Astrid Spitz , Susanne Wieland , Hendrik Hellmuth , Karl-Heinz Maurer
CPC分类号： C12N9/54 , C11D3/386 , C11D3/38681
摘要： Proteases encompassing an amino acid sequence that is at least 70% identical to the amino acid sequence indicated in SEQ ID NO. 1 over its entire length, and exhibit the amino acid substitution I21V in the count in accordance with SEQ ID NO. 1, resp. agents that encompass such proteases, display very good cleaning performance on protease-sensitive stains.
摘要翻译： 包含与SEQ ID NO：1所示的氨基酸序列至少70％相同的氨基酸序列的蛋白酶。 1，并且按照SEQ ID NO：1显示计数中的氨基酸取代度I21V。 1，或 包含这种蛋白酶的试剂在蛋白酶敏感染色剂上表现出非常好的清洁性能。
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公开(公告)号：US09365844B2
公开(公告)日：2016-06-14
申请号：US13583602
申请日：2011-03-10
申请人： Petra Siegert , Ulrich Schwaneberg , Ronny Martinez , Marion Merkel , Astrid Spitz , Susanne Wieland , Hendrik Hellmuth , Karl-Heinz Maurer
发明人： Petra Siegert , Ulrich Schwaneberg , Ronny Martinez , Marion Merkel , Astrid Spitz , Susanne Wieland , Hendrik Hellmuth , Karl-Heinz Maurer
CPC分类号： C12N9/54 , C11D3/386 , C11D3/38681
摘要： Proteases encompassing an amino acid sequence that is at least 70% identical to the amino acid sequence indicated in SEQ ID NO. 1 over its entire length, and exhibit the amino acid substitution I21V in the count in accordance with SEQ ID NO. 1, agents that encompass such proteases, display very good cleaning performance on protease-sensitive stains.
摘要翻译： 包含与SEQ ID NO：1所示的氨基酸序列至少70％相同的氨基酸序列的蛋白酶。 1，并且按照SEQ ID NO：1显示计数中的氨基酸取代度I21V。 1，包含这种蛋白酶的试剂在蛋白酶敏感性污渍上表现出非常好的清洁性能。
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公开(公告)号：US07510859B2
公开(公告)日：2009-03-31
申请号：US11156062
申请日：2005-06-17
IPC分类号： C12N9/16 , C12N15/55 , C12N15/74 , C12N15/75 , A61Q5/10 , A61Q11/02 , C11D3/386 , C11D3/395 , C12P7/02 , C12N9/54 , C12N15/70 , A61K8/38 , A61Q5/08
CPC分类号： C11D3/38636 , C12N9/54
摘要： The invention relates to novel perhydrolases, derived from the protease Carlsberg by amino acid exchange in positions 11, 15, 21, 38, 50, 54, 58, 77, 83, 89, 93, 96, 107, 117, 120, 134, 135, 136, 140, 147, 150, 154, 155, 160, 161, 171, 179, 180, 181, 194, 205, 208, 213, 216, 217, 238, 239, 251, 253, 257, and/or 261. The invention further relates to methods for production of said novel perhydrolases, products comprising said novel perhydrolases, particularly bodycare, haircare, shampoo, hair-dyeing, hair-bleaching, oral-care, dental-dare, dental-prosthesis-care, cosmetic, therapeutic (textile) washing, cleaning, rinsing, handwash, washing-up and dish-washing products, and corresponding applications of said novel perhydrolases.
摘要翻译： 本发明涉及新的过水解酶，其通过在11,15,21,38,50,54,58,77,83,89,93,96,107,117， 135,136,140,147,150,154,155,160,161,171,179,180,181,194,205,208,213,216,217,238,239,251,253,257和/或其中的/ 本发明还涉及生产所述新型过水解酶的方法，包含所述新型过水解酶的产品，特别是身体护理，护发，洗发剂，染发剂，脱毛剂，口腔护理剂，牙科用品，牙科假体护理 ，化妆品，治疗（纺织品）洗涤，清洁，漂洗，洗手和洗碗产品，以及所述新型过水解酶的相应应用。
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公开(公告)号：US20050281773A1
公开(公告)日：2005-12-22
申请号：US11156062
申请日：2005-06-17
CPC分类号： C11D3/38636 , C12N9/54
摘要： The invention relates to novel perhydrolases, derived from the protease Carlsberg by amino acid exchange in positions 11, 15, 21, 38, 50, 54, 58, 77, 83, 89, 93, 96, 107, 117, 120, 134, 135, 136, 140, 147, 150, 154, 155, 160, 161, 171, 179, 180, 181, 194, 205, 208, 213, 216, 217, 238, 239, 251, 253, 257, and/or 261. The invention further relates to methods for production of said novel perhydrolases, products comprising said novel perhydrolases, particularly bodycare, haircare, shampoo, hair-dyeing, hair-bleaching, oral-care, dental-dare, dental-prosthesis-care, cosmetic, therapeutic (textile) washing, cleaning, rinsing, handwash, washing-up and dish-washing products, and corresponding applications of said novel perhydrolases.
摘要翻译： 本发明涉及新的过水解酶，其通过在11,15,21,38,50,54,58,77,83,89,93,96,107,117， 135,136,140,147,150,154,155,160,161,171,179,180,181,194,205,208,213,216,217,238,239,251,253,257和/或其中的/ 本发明还涉及生产所述新型过水解酶的方法，包含所述新型过水解酶的产品，特别是身体护理，护发，洗发剂，染发剂，脱毛剂，口腔护理剂，牙科用品，牙科假体护理 ，化妆品，治疗（纺织品）洗涤，清洁，漂洗，洗手和洗碗产品，以及所述新型过水解酶的相应应用。
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6.发明申请Novel Alkaline Protease from Bacillus Gibsonii and Washing and Cleaning Agents containing said Novel Alkaline Protease 审中-公开来自芽孢杆菌的新型碱性蛋白酶和含有所述新型碱性蛋白酶的洗涤和清洁剂公开(公告)号：US20090275493A1
公开(公告)日：2009-11-05
申请号：US12502459
申请日：2009-07-14
申请人： Petra Siegert , Susanne Wieland , Julia Engelskirchen , Marion Merkel , Karl-Heinz Maurer , Cornelius Bessler
发明人： Petra Siegert , Susanne Wieland , Julia Engelskirchen , Marion Merkel , Karl-Heinz Maurer , Cornelius Bessler
摘要： A novel subtilisin-type alkaline protease from Bacillus gibsonii and to sufficiently related proteins and the derivatives thereof. Also, washing and cleaning agents comprising the novel subtilisin-type alkaline protease, sufficiently related proteins and the derivatives thereof, corresponding washing and cleaning methods and their use in washing and cleaning agents, and other possible technical uses.
摘要翻译： 来自芽孢杆菌的新型枯草杆菌蛋白酶型碱性蛋白酶和足够相关的蛋白质及其衍生物。 此外，包含新的枯草杆菌蛋白酶型碱性蛋白酶，足够相关的蛋白质及其衍生物的洗涤和清洁剂，相应的洗涤和清洁方法及其在洗涤和清洁剂中的用途以及其它可能的技术用途。
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7.发明申请SUBTILISIN FROM BACILLUS PUMILUS AND DETERGENT AND CLEANING AGENTS CONTAINING SAID NOVEL SUBTILISIN 审中-公开来自BACILLUS PUMILUS和洗涤剂和含有新型分散素的清洁剂的分散体公开(公告)号：US20090170745A1
公开(公告)日：2009-07-02
申请号：US12268702
申请日：2008-11-11
IPC分类号： C11D7/42 , C12N15/57 , C12N15/75 , C12N9/54 , C12S11/00 , C12S9/00 , C12N15/77 , C12N15/70 , C12N1/21
CPC分类号： C12N9/54 , A61K38/00 , C11D3/386 , C12Y304/21062 , Y02A50/473
摘要： A novel subtilisin-type alkaline protease from Bacillus pumilus and sufficiently related proteins and derivatives thereof. Also washing and cleaning agents comprising the novel subtilisin-type alkaline protease, sufficiently related proteins and derivatives thereof, corresponding washing and cleaning methods, and washing and cleaning agents and other possible technical uses.
摘要翻译： 来自短小芽孢杆菌的新型枯草杆菌蛋白酶型碱性蛋白酶和足够相关的蛋白质及其衍生物。 还有洗涤和清洁剂，其包含新的枯草杆菌蛋白酶型碱性蛋白酶，足够相关的蛋白质及其衍生物，相应的洗涤和清洁方法，以及洗涤和清洁剂以及其它可能的技术用途。
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公开(公告)号：US20100234267A1
公开(公告)日：2010-09-16
申请号：US12685215
申请日：2010-01-11
申请人： Petra Siegert , Susanne Wieland , Karl-Heinz Maurer , Cornelius Bessler , Doris Ribitsch , Sonja Heumann , Georg Gübitz , Wolfgang Karl , Peter Remler , Helmut Schwab , Gabriele Berg , Jochen Gerlach
发明人： Petra Siegert , Susanne Wieland , Karl-Heinz Maurer , Cornelius Bessler , Doris Ribitsch , Sonja Heumann , Georg Gübitz , Wolfgang Karl , Peter Remler , Helmut Schwab , Gabriele Berg , Jochen Gerlach
摘要： The present invention relates to agent compositions, in particular washing and cleaning agents, that contain a protease from a bacterial strain of the species Stenotrophomonas maltophilia, and to said proteases themselves. The invention further relates to cleaning methods in which said agents are used, and to uses of said agents. The invention further relates to the manufacture and use of these proteases themselves.
摘要翻译： 本发明涉及含有来自嗜麦芽寡养单胞菌属细菌菌株的蛋白酶和所述蛋白酶本身的药剂组合物，特别是洗涤和清洁剂。 本发明还涉及其中使用所述试剂的清洁方法以及所述试剂的用途。 本发明还涉及这些蛋白酶本身的制造和使用。
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9.发明申请STORAGE-STABLE LIQUID WASHING OR CLEANING AGENT CONTAINING PROTEASE AND AMYLASE 审中-公开储存稳定的液体清洗剂或清洁剂，含有蛋白酶和淀粉酶公开(公告)号：US20140018282A1
公开(公告)日：2014-01-16
申请号：US13993898
申请日：2011-12-13
IPC分类号： C11D3/386
摘要： According to the invention, storage stability in terms of amylolytic activity is to be improved in a liquid washing or cleaning agent which comprises a protease and amylase. This is achieved by the use of a protease which comprises an amino acid sequence which is at least 80% identical to the amino acid sequence specified in SEQ ID NO. 1 and which has the amino acid glutamic acid (E) or aspartic acid (D) or the amino acid asparagine (N) or glutamine (Q) or the amino acid alanine (A) or glycine (G) or serine (S) at position 99 in the count according to SEQ ID NO. 1.
摘要翻译： 根据本发明，在包含蛋白酶和淀粉酶的液体洗涤剂或清洁剂中，淀粉分解活性的储存稳定性得到改善。 这通过使用蛋白酶来实现，所述蛋白酶包含与SEQ ID NO：1中规定的氨基酸序列至少80％相同的氨基酸序列。 1，其具有氨基酸谷氨酸（E）或天冬氨酸（D）或氨基酸天冬酰胺（N）或谷氨酰胺（Q）或氨基酸丙氨酸（A）或甘氨酸（G）或丝氨酸（S） 根据SEQ ID NO。 1。
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公开(公告)号：US20100196991A1
公开(公告)日：2010-08-05
申请号：US12760581
申请日：2010-04-15
CPC分类号： C12N9/52 , C11D3/38609 , C12N9/58 , C12Y304/21062
摘要： The present invention relates to a method for obtaining novel protein variants by circular permutation, and to the novel protein variants obtained by said method.
摘要翻译： 本发明涉及通过循环排列获得新型蛋白质变体的方法，以及通过所述方法获得的新型蛋白质变体。
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