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公开(公告)号：US20070020381A1
公开(公告)日：2007-01-25
申请号：US11527893
申请日：2006-09-26
申请人： Syed Hossainy , Gordon Stewart , Mark Williams , Jeff Royal , Paul Consigny , Dorie Happ , Kurt Scheinpflug , Ty Hu
发明人： Syed Hossainy , Gordon Stewart , Mark Williams , Jeff Royal , Paul Consigny , Dorie Happ , Kurt Scheinpflug , Ty Hu
IPC分类号： A61L33/00
CPC分类号： A61F2/844 , A61F2250/0067 , A61L27/54 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606
摘要： A method and coating for reducing the release rate of an active agent from an implantable device, such as a stent, is disclosed.
摘要翻译： 公开了一种用于降低活性剂从可植入装置（例如支架）的释放速率的方法和涂层。
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公开(公告)号：US20070032853A1
公开(公告)日：2007-02-08
申请号：US10108004
申请日：2002-03-27
申请人： Syed Hossainy , Gordon Stewart , Mark Williams , Jeff Royal , Paul Consigny , Dorie Happ , Kurt Scheinpflug , Ty Hu
发明人： Syed Hossainy , Gordon Stewart , Mark Williams , Jeff Royal , Paul Consigny , Dorie Happ , Kurt Scheinpflug , Ty Hu
IPC分类号： A61F2/06
CPC分类号： A61F2/844 , A61F2250/0067 , A61L27/54 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606
摘要： A method and coating for reducing the release rate of an active agent from an implantable device, such as a stent, is disclosed.
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公开(公告)号：US20070026131A1
公开(公告)日：2007-02-01
申请号：US11527826
申请日：2006-09-26
申请人： Syed Hossainy , Gordon Stewart , Mark Williams , Jeff Royal , Paul Consigny , Dorie Happ , Kurt Scheinpflug , Ty Hu
发明人： Syed Hossainy , Gordon Stewart , Mark Williams , Jeff Royal , Paul Consigny , Dorie Happ , Kurt Scheinpflug , Ty Hu
CPC分类号： A61F2/844 , A61F2250/0067 , A61L27/54 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606
摘要： A method and coating for reducing the release rate of an active agent from an implantable device, such as a stent, is disclosed.
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公开(公告)号：US20070020382A1
公开(公告)日：2007-01-25
申请号：US11527971
申请日：2006-09-26
申请人： Syed Hossainy , Gordon Stewart , Mark Williams , Jeff Royal , Paul Consigny , Dorie Happ , Kurt Scheinpflug , Ty Hu
发明人： Syed Hossainy , Gordon Stewart , Mark Williams , Jeff Royal , Paul Consigny , Dorie Happ , Kurt Scheinpflug , Ty Hu
IPC分类号： A61L33/00
CPC分类号： A61F2/844 , A61F2250/0067 , A61L27/54 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606
摘要： A method and coating for reducing the release rate of an active agent from an implantable device, such as a stent, is disclosed.
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公开(公告)号：US08173199B2
公开(公告)日：2012-05-08
申请号：US11527893
申请日：2006-09-26
申请人： Syed F. A. Hossainy , Gordon Stewart , Mark A. Williams , Jeff Royal , Paul M. Consigny , Dorrie M. Happ , Kurt Scheinpflug , Ty Hu
发明人： Syed F. A. Hossainy , Gordon Stewart , Mark A. Williams , Jeff Royal , Paul M. Consigny , Dorrie M. Happ , Kurt Scheinpflug , Ty Hu
CPC分类号： A61F2/844 , A61F2250/0067 , A61L27/54 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606
摘要： A method and coating for reducing the release rate of an active agent from an implantable device, such as a stent, is disclosed.
摘要翻译： 公开了一种用于降低活性剂从可植入装置（例如支架）的释放速率的方法和涂层。
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6.发明授权Method of coating a stent with a release polymer for 40-O-(2-hydroxy)ethyl-rapamycin 有权用40-O-（2-羟基）乙基雷帕霉素的释放聚合物涂覆支架的方法公开(公告)号：US08961588B2
公开(公告)日：2015-02-24
申请号：US11527971
申请日：2006-09-26
申请人： Syed F. A. Hossainy , Gordon Stewart , Mark A. Williams , Jeff Royal , Paul M. Consigny , Dorie M. Happ , Kurt Scheinpflug , Ty Hu
发明人： Syed F. A. Hossainy , Gordon Stewart , Mark A. Williams , Jeff Royal , Paul M. Consigny , Dorie M. Happ , Kurt Scheinpflug , Ty Hu
CPC分类号： A61F2/844 , A61F2250/0067 , A61L27/54 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606
摘要： A method of coating a stent is presented such that less than 50% of the total amount of 40-O-(2-hydroxyl)ethyl-rapamycin, or an analog or derivative thereof, is released in vivo in a 24 hour period, wherein the method comprises exposing the coating to sufficient temperature to modify the structure of the polymer.
摘要翻译： 提出了一种涂覆支架的方法，使得在24小时内体内释放40-O-（2-羟基）乙基雷帕霉素或其类似物或衍生物的总量的少于50％，其中 该方法包括将涂层暴露于足够的温度以改变聚合物的结构。
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公开(公告)号：US07682647B2
公开(公告)日：2010-03-23
申请号：US10603794
申请日：2003-06-25
申请人： Syed F. A. Hossainy , Fuh-Wei Tang , Stephen D. Pacetti , Jeff Royal , Dorie M. Happ , Kurt Scheinpflug , Ty Hu
发明人： Syed F. A. Hossainy , Fuh-Wei Tang , Stephen D. Pacetti , Jeff Royal , Dorie M. Happ , Kurt Scheinpflug , Ty Hu
CPC分类号： A61L27/34 , A61F2/91 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/146 , A61L31/16 , A61L33/0011 , A61L2300/416 , A61L2300/602 , A61L2300/606 , C08L29/04
摘要： A coating and a method of coating an implantable medical device, such as a stent, is disclosed. The method includes subjecting the coating to a thermal condition which can result in reduction of the rate of release of an active agent from the coating subsequent to the implantation of the device.
摘要翻译： 公开了涂覆和涂覆可植入医疗装置（例如支架）的方法。 该方法包括使涂层经受热状态，其可导致在设备植入之后活性剂从涂层中释放的速率降低。
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公开(公告)号：US20100136213A1
公开(公告)日：2010-06-03
申请号：US12699127
申请日：2010-02-03
申请人： Syed F.A. Hossainy , Fuh-Wei Tang , Stephen D. Pacetti , Jeff Royal , Dorrie M. Happ , Kurt Scheinpflug , Ty Hu
发明人： Syed F.A. Hossainy , Fuh-Wei Tang , Stephen D. Pacetti , Jeff Royal , Dorrie M. Happ , Kurt Scheinpflug , Ty Hu
IPC分类号： B05D3/02
CPC分类号： A61L27/34 , A61F2/91 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/146 , A61L31/16 , A61L33/0011 , A61L2300/416 , A61L2300/602 , A61L2300/606 , C08L29/04
摘要： A coating and a method of coating an implantable medical device, such as a stent, is disclosed. The method includes subjecting the coating to a thermal condition such as a temperature above the glass transition temperature of a polymer included in the coating.
摘要翻译： 公开了涂覆和涂覆可植入医疗装置（例如支架）的方法。 该方法包括使涂层经受诸如包含在涂层中的聚合物的玻璃化转变温度以上的温度的热条件。
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公开(公告)号：US08053019B2
公开(公告)日：2011-11-08
申请号：US12699127
申请日：2010-02-03
申请人： Syed F. A. Hossainy , Fuh-Wei Tang , Stephen D. Pacetti , Jeff Royal , Dorie M. Happ , Kurt Scheinpflug , Ty Hu
发明人： Syed F. A. Hossainy , Fuh-Wei Tang , Stephen D. Pacetti , Jeff Royal , Dorie M. Happ , Kurt Scheinpflug , Ty Hu
CPC分类号： A61L27/34 , A61F2/91 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/146 , A61L31/16 , A61L33/0011 , A61L2300/416 , A61L2300/602 , A61L2300/606 , C08L29/04
摘要： A coating and a method of coating an implantable medical device, such as a stent, is disclosed. The method includes subjecting the coating to a thermal condition such as a temperature above the glass transition temperature of a polymer included in the coating.
摘要翻译： 公开了涂覆和涂覆可植入医疗装置（例如支架）的方法。 该方法包括使涂层经受诸如包含在涂层中的聚合物的玻璃化转变温度以上的温度的热条件。
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公开(公告)号：US20090030508A1
公开(公告)日：2009-01-29
申请号：US12246420
申请日：2008-10-06
申请人： Fuh-Wei Tang , Syed F.A. Hossainy , Dorie Happ , Ty Hu
发明人： Fuh-Wei Tang , Syed F.A. Hossainy , Dorie Happ , Ty Hu
IPC分类号： A61F2/06
CPC分类号： B29C39/003 , A61F2/91
摘要： A stent mandrel fixture for supporting a stent during the application of a coating substance is provided.
摘要翻译： 提供了一种用于在施加涂层物质期间支撑支架的支架心轴夹具。
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