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公开(公告)号：US20100136213A1
公开(公告)日：2010-06-03
申请号：US12699127
申请日：2010-02-03
申请人： Syed F.A. Hossainy , Fuh-Wei Tang , Stephen D. Pacetti , Jeff Royal , Dorrie M. Happ , Kurt Scheinpflug , Ty Hu
发明人： Syed F.A. Hossainy , Fuh-Wei Tang , Stephen D. Pacetti , Jeff Royal , Dorrie M. Happ , Kurt Scheinpflug , Ty Hu
IPC分类号： B05D3/02
CPC分类号： A61L27/34 , A61F2/91 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/146 , A61L31/16 , A61L33/0011 , A61L2300/416 , A61L2300/602 , A61L2300/606 , C08L29/04
摘要： A coating and a method of coating an implantable medical device, such as a stent, is disclosed. The method includes subjecting the coating to a thermal condition such as a temperature above the glass transition temperature of a polymer included in the coating.
摘要翻译： 公开了涂覆和涂覆可植入医疗装置（例如支架）的方法。 该方法包括使涂层经受诸如包含在涂层中的聚合物的玻璃化转变温度以上的温度的热条件。
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公开(公告)号：US07682647B2
公开(公告)日：2010-03-23
申请号：US10603794
申请日：2003-06-25
申请人： Syed F. A. Hossainy , Fuh-Wei Tang , Stephen D. Pacetti , Jeff Royal , Dorie M. Happ , Kurt Scheinpflug , Ty Hu
发明人： Syed F. A. Hossainy , Fuh-Wei Tang , Stephen D. Pacetti , Jeff Royal , Dorie M. Happ , Kurt Scheinpflug , Ty Hu
CPC分类号： A61L27/34 , A61F2/91 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/146 , A61L31/16 , A61L33/0011 , A61L2300/416 , A61L2300/602 , A61L2300/606 , C08L29/04
摘要： A coating and a method of coating an implantable medical device, such as a stent, is disclosed. The method includes subjecting the coating to a thermal condition which can result in reduction of the rate of release of an active agent from the coating subsequent to the implantation of the device.
摘要翻译： 公开了涂覆和涂覆可植入医疗装置（例如支架）的方法。 该方法包括使涂层经受热状态，其可导致在设备植入之后活性剂从涂层中释放的速率降低。
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公开(公告)号：US08053019B2
公开(公告)日：2011-11-08
申请号：US12699127
申请日：2010-02-03
申请人： Syed F. A. Hossainy , Fuh-Wei Tang , Stephen D. Pacetti , Jeff Royal , Dorie M. Happ , Kurt Scheinpflug , Ty Hu
发明人： Syed F. A. Hossainy , Fuh-Wei Tang , Stephen D. Pacetti , Jeff Royal , Dorie M. Happ , Kurt Scheinpflug , Ty Hu
CPC分类号： A61L27/34 , A61F2/91 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/146 , A61L31/16 , A61L33/0011 , A61L2300/416 , A61L2300/602 , A61L2300/606 , C08L29/04
摘要： A coating and a method of coating an implantable medical device, such as a stent, is disclosed. The method includes subjecting the coating to a thermal condition such as a temperature above the glass transition temperature of a polymer included in the coating.
摘要翻译： 公开了涂覆和涂覆可植入医疗装置（例如支架）的方法。 该方法包括使涂层经受诸如包含在涂层中的聚合物的玻璃化转变温度以上的温度的热条件。
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4.发明申请POLYMERS CONTAINING POLY(HYDROXYALKANOATES) AND AGENTS FOR USE WITH MEDICAL ARTICLES AND METHODS OF FABRICATING THE SAME 有权含有聚（羟基甘草酸酯）的聚合物和用于医药制品的试剂及其制备方法公开(公告)号：US20110274733A1
公开(公告)日：2011-11-10
申请号：US13183966
申请日：2011-07-15
IPC分类号： A61K9/00 , C08G12/26 , A61K31/765 , C08G69/26
CPC分类号： C08G63/912 , C08B37/0072 , C08B37/0075 , C08G63/06 , C08G63/664 , C08L1/08 , C08L1/286 , C08L5/02 , C08L5/08 , C08L5/10 , C08L25/18 , C08L33/26 , C08L39/06 , C08L67/04 , C08L71/02 , C08L77/12 , C09D101/286 , C09D105/02 , C09D105/08 , C09D105/10 , C09D167/04 , C08L2666/04 , C08L2666/26 , C08L2666/20 , C08L2666/06 , C08L2666/22
摘要： Embodiments of the present invention provides medical devices comprising poly(hydroxyalkanoates) and agents.
摘要翻译： 本发明的实施方案提供包含聚（羟基链烷酸酯）和试剂的医疗装置。
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5.发明授权Polymers containing poly(hydroxyalkanoates) and agents for use with medical articles and methods of fabricating the same 有权含有聚（羟基链烷酸酯）的聚合物和用于医疗制品的试剂及其制造方法公开(公告)号：US08007775B2
公开(公告)日：2011-08-30
申请号：US11027955
申请日：2004-12-30
IPC分类号： A61K31/765
CPC分类号： C08G63/912 , C08B37/0072 , C08B37/0075 , C08G63/06 , C08G63/664 , C08L1/08 , C08L1/286 , C08L5/02 , C08L5/08 , C08L5/10 , C08L25/18 , C08L33/26 , C08L39/06 , C08L67/04 , C08L71/02 , C08L77/12 , C09D101/286 , C09D105/02 , C09D105/08 , C09D105/10 , C09D167/04 , C08L2666/04 , C08L2666/26 , C08L2666/20 , C08L2666/06 , C08L2666/22
摘要： Polymers containing poly(hydroxyalkanoates) and agents for use with medical articles and methods of fabricating the same are disclosed. The medical article generally comprises an implantable substrate having a coating, and the coating contains a poly(hydroxyalkanoate).
摘要翻译： 公开了含有聚（羟基链烷酸酯）的聚合物和用于医疗制品的试剂及其制造方法。 医疗制品通常包括具有涂层的可植入基底，并且该涂层含有聚（羟基链烷酸酯）。
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公开(公告)号：US20100198342A1
公开(公告)日：2010-08-05
申请号：US12723565
申请日：2010-03-12
申请人： Syed F.A. Hossainy , Stephen D. Pacetti , Keith E. Fong , Vinayak Bhat , Deborra Sanders Millare , Judy A. Guruwaiya , Daryush Mirzaee , Evgenia Mandrusov
发明人： Syed F.A. Hossainy , Stephen D. Pacetti , Keith E. Fong , Vinayak Bhat , Deborra Sanders Millare , Judy A. Guruwaiya , Daryush Mirzaee , Evgenia Mandrusov
IPC分类号： A61F2/06
CPC分类号： A61L27/34 , A61L27/306 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L33/0011 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2300/608 , A61L2420/02 , A61L2420/08 , C08L29/04
摘要： Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients.
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公开(公告)号：US20070292495A1
公开(公告)日：2007-12-20
申请号：US11454813
申请日：2006-06-15
CPC分类号： A61K9/5115 , A61K9/0009 , A61K9/127 , A61K41/0019 , A61K41/0028
摘要： Nano-constructs comprising nanoshells and methods of using the nano-constructs for treating or ameliorating a medical condition are provided.
摘要翻译： 提供包含纳米壳的纳米构建体和使用纳米构建体治疗或改善医学状况的方法。
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公开(公告)号：US20120185034A1
公开(公告)日：2012-07-19
申请号：US13427608
申请日：2012-03-22
申请人： Syed F.A. Hossainy , Stephen D. Pacetti , Keith E. Fong , Vinayak Bhat , Deborra Sanders Millare , Judy A. Guruwaiya , Daryush Mirzaee , Evgenia Mandrusov
发明人： Syed F.A. Hossainy , Stephen D. Pacetti , Keith E. Fong , Vinayak Bhat , Deborra Sanders Millare , Judy A. Guruwaiya , Daryush Mirzaee , Evgenia Mandrusov
IPC分类号： A61F2/82
CPC分类号： A61L27/34 , A61L27/306 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L33/0011 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2300/608 , A61L2420/02 , A61L2420/08 , C08L29/04
摘要： Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can serve as a primer coating for subsequent coatings that can be used for the delivery of an active ingredient or a combination of active ingredients.
摘要翻译： 提供用于可植入装置或腔内假体（例如支架）的涂层，包括形成涂层的方法。 涂层可以用作后续涂层的底漆涂层，其可用于递送活性成分或活性成分的组合。
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公开(公告)号：US20100323093A1
公开(公告)日：2010-12-23
申请号：US12766758
申请日：2010-04-23
IPC分类号： B05D3/02
CPC分类号： B29C65/76 , A61F2/82 , A61F2/86 , A61F2/91 , A61F2210/0004 , A61F2210/0076 , A61F2240/001 , A61F2250/0067 , A61F2310/00389 , A61L31/14 , A61L31/148 , A61L2420/02 , B05D1/38 , B05D3/0254 , B05D3/0473 , B29C65/10 , B29K2067/046 , B29K2105/258 , B29L2031/7534
摘要： Various embodiments of methods for coating stents are described herein. Applying a composition including polymer component and solvent to a stent substrate followed by exposing the polymer component to a temperature equal to or greater than a Tg of the polymer component is disclosed. Repeating the applying and exposing one or more times to form a coating with the result that the solvent content of the coating after the final exposing step is at a level suitable for a finished stent is further disclosed.
摘要翻译： 本文描述了用于涂覆支架的方法的各种实施例。 公开了将包含聚合物组分和溶剂的组合物施用到支架基底，然后将聚合物组分暴露于等于或大于聚合物组分的Tg的温度。 重复施加和暴露一次或多次以形成涂层，结果是在最终曝光步骤之后涂层的溶剂含量处于适合成品支架的水平。
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公开(公告)号：US20100198341A1
公开(公告)日：2010-08-05
申请号：US12723561
申请日：2010-03-12
申请人： Syed F.A. Hossainy , Stephen D. Pacetti , Keith E. Fong , Vinayak Bhat , Deborra Sanders Millare , Judy A. Guruwaiya , Daryush Mirzaee , Evgenia Mandrusov
发明人： Syed F.A. Hossainy , Stephen D. Pacetti , Keith E. Fong , Vinayak Bhat , Deborra Sanders Millare , Judy A. Guruwaiya , Daryush Mirzaee , Evgenia Mandrusov
IPC分类号： A61F2/06
CPC分类号： A61L27/34 , A61L27/306 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L33/0011 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2300/608 , A61L2420/02 , A61L2420/08 , C08L29/04
摘要： Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients.
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