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公开(公告)号:US06805784B2
公开(公告)日:2004-10-19
申请号:US09797698
申请日:2001-03-05
申请人: Syozo Kasai , Kiyoshi Tsukada , Toshiaki Kita , Tomonari Morioka
发明人: Syozo Kasai , Kiyoshi Tsukada , Toshiaki Kita , Tomonari Morioka
IPC分类号: G01N27453
CPC分类号: G01N27/44782 , G01N27/44721
摘要: The structure of a capillary head section is made such that the liquid contacting surfaces of a capillary holder, a capillary, and an adhesive form a plane surface, and this shared liquid contacting surface is made a mirror surface with a surface roughness of 3.2 s or less. In the shared liquid contacting surface, the ratio of the total area of the capillaries to the internal diameter area of the capillary holder is made 60 to 73%.
摘要翻译: 毛细管头部分的结构使得毛细管支架,毛细管和粘合剂的液体接触表面形成平面,并且该共用液体接触表面被制成具有3.2s的表面粗糙度的镜面或 减。 在共享液体接触表面中,毛细管支架的总面积与毛细管支架的内径面积的比率为60至73%。
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公开(公告)号:US20100288642A1
公开(公告)日:2010-11-18
申请号:US12843103
申请日:2010-07-26
申请人: Yasushi Shimizu , Toshiaki Kita , Kiyoshi Tsukada , Akihiro Suzuki , Tomonari Morioka , Masaya Kojima , Ryoji Inaba , Daizo Tokinaga , Shuhei Yamamoto , Yoshiyuki Okishima , Masao Fukunaga , Takayasu Furukawa , Tomohiro Shoji
发明人: Yasushi Shimizu , Toshiaki Kita , Kiyoshi Tsukada , Akihiro Suzuki , Tomonari Morioka , Masaya Kojima , Ryoji Inaba , Daizo Tokinaga , Shuhei Yamamoto , Yoshiyuki Okishima , Masao Fukunaga , Takayasu Furukawa , Tomohiro Shoji
IPC分类号: G01N27/26
CPC分类号: G01N27/44721 , G01N27/44782
摘要: A capillary array includes a light detection portion, a sample supply portion, a buffer solution supply portion and a voltage application portion which are necessary functions for electrophoresis, thereby, when assembling the capillary array into an electrophoresis apparatus, the same can be immediately used. Accordingly, a capillary array is provided which can be easily incorporated into an electrophoresis apparatus.
摘要翻译: 毛细管阵列包括作为电泳所需功能的光检测部分,样品供应部分,缓冲溶液供应部分和电压施加部分,从而当将毛细管阵列组装到电泳装置中时可以立即使用。 因此,提供了可以容易地并入电泳装置中的毛细管阵列。
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公开(公告)号:US06977034B2
公开(公告)日:2005-12-20
申请号:US10239765
申请日:2000-12-04
IPC分类号: G01N27/447 , G01N27/453 , G01N30/02
CPC分类号: G01N27/44782 , G01N27/44721
摘要: A capillary array comprising multiple capillaries and two holding substrates for arranging the aforementioned multiple capillaries in a substantially plane surface by sandwiching at least some of these capillaries mutually. One of the holding substrates has a detection window for transmitting the detected light emitted by a test sample by irradiation of light. Especially, this detection window comprises multiple light transmission areas provided to correspond to each capillary to transmit the detected light, and light cut-off areas provided between these light transmission areas to cut off the detected light. These light cut-off areas cut off light reflected from the surface of capillaries and hence improve the SN ratio, thereby ensuring high-precision detection.
摘要翻译: 毛细管阵列,其包括多个毛细管和两个保持基板,用于通过相互夹住这些毛细管中的至少一些来将上述多个毛细管布置在基本上平面的表面中。 保持基板中的一个具有用于通过照射光透射由测试样品发射的检测到的光的检测窗口。 特别地,该检测窗口包括多个透光区域,其设置为对应于每个毛细管以透射检测到的光,以及设置在这些光透射区域之间的遮光区域以切断检测到的光。 这些遮光区域切断从毛细管表面反射的光,从而提高SN比,从而确保高精度检测。
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公开(公告)号:US08142635B2
公开(公告)日:2012-03-27
申请号:US12843103
申请日:2010-07-26
申请人: Yasushi Shimizu , Toshiaki Kita , Kiyoshi Tsukada , Akihiro Suzuki , Tomonari Morioka , Masaya Kojima , Ryoji Inaba , Daizo Tokinaga , Shuhei Yamamoto , Yoshiyuki Okishima , Masao Fukunaga , Takayasu Furukawa , Tomohiro Shoji
发明人: Yasushi Shimizu , Toshiaki Kita , Kiyoshi Tsukada , Akihiro Suzuki , Tomonari Morioka , Masaya Kojima , Ryoji Inaba , Daizo Tokinaga , Shuhei Yamamoto , Yoshiyuki Okishima , Masao Fukunaga , Takayasu Furukawa , Tomohiro Shoji
IPC分类号: C02F1/40
CPC分类号: G01N27/44721 , G01N27/44782
摘要: A capillary array includes a light detection portion, a sample supply portion, a buffer solution supply portion and a voltage application portion which are necessary functions for electrophoresis, thereby, when assembling the capillary array into an electrophoresis apparatus, the same can be immediately used. Accordingly, a capillary array is provided which can be easily incorporated into an electrophoresis apparatus.
摘要翻译: 毛细管阵列包括作为电泳所需功能的光检测部分,样品供应部分,缓冲溶液供应部分和电压施加部分,从而当将毛细管阵列组装到电泳装置中时可以立即使用。 因此,提供了可以容易地并入电泳装置中的毛细管阵列。
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公开(公告)号:US07785458B2
公开(公告)日:2010-08-31
申请号:US11300377
申请日:2005-12-15
申请人: Yasushi Shimizu , Toshiaki Kita , Kiyoshi Tsukada , Akihiro Suzuki , Tomonari Morioka , Masaya Kojima , Ryoji Inaba , Daizo Tokinaga , Shuhei Yamamoto , Yoshiyuki Okishima , Masao Fukunaga , Takayasu Furukawa , Tomohiro Shoji
发明人: Yasushi Shimizu , Toshiaki Kita , Kiyoshi Tsukada , Akihiro Suzuki , Tomonari Morioka , Masaya Kojima , Ryoji Inaba , Daizo Tokinaga , Shuhei Yamamoto , Yoshiyuki Okishima , Masao Fukunaga , Takayasu Furukawa , Tomohiro Shoji
IPC分类号: C02F1/40
CPC分类号: G01N27/44721 , G01N27/44782
摘要: A capillary array includes a light detection portion, a sample supply portion, a buffer solution supply portion and a voltage application portion which are necessary functions for electrophoresis, thereby, when assembling the capillary array into an electrophoresis apparatus, the same can be immediately used. Accordingly, a capillary array is provided which can be easily incorporated into an electrophoresis apparatus.
摘要翻译: 毛细管阵列包括作为电泳所需功能的光检测部分,样品供应部分,缓冲溶液供应部分和电压施加部分,从而当将毛细管阵列组装到电泳装置中时可以立即使用。 因此,提供了可以容易地并入电泳装置中的毛细管阵列。
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公开(公告)号:US07445701B2
公开(公告)日:2008-11-04
申请号:US11204116
申请日:2005-08-16
IPC分类号: G01N27/453
CPC分类号: G01N27/44782 , G01N27/44721
摘要: A capillary array includes multiple capillaries and two holding substrates for arranging the aforementioned multiple capillaries in a substantially plane surface by sandwiching at least some of these capillaries mutually. One of the holding substrates has a detection window for transmitting the detected light emitted by a test sample by irradiation of light. Especially, this detection window includes multiple light transmission areas provided to correspond to each capillary to transmit the detected light, and light cut-off areas provided between these light transmission areas to cut off the detected light. These light cut-off areas cut off light reflected from the surface of capillaries and hence improve the SN ratio, thereby ensuring high-precision detection.
摘要翻译: 毛细管阵列包括多个毛细管和两个保持基板,用于通过相互夹住这些毛细管中的至少一些来将上述多个毛细管布置在基本上平面的表面中。 保持基板中的一个具有用于通过照射光透射由测试样品发射的检测到的光的检测窗口。 特别地,该检测窗口包括多个透光区域,其设置为对应于每个毛细管以透射检测到的光,以及设置在这些光透射区域之间的遮光区域,以切断检测到的光。 这些遮光区域切断从毛细管表面反射的光,从而提高SN比,从而确保高精度检测。
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公开(公告)号:US20060091012A1
公开(公告)日:2006-05-04
申请号:US11300377
申请日:2005-12-15
申请人: Yasushi Shimizu , Toshiaki Kita , Kiyoshi Tsukada , Akihiro Suzuki , Tomonari Morioka , Masaya Kojima , Ryoji Inaba , Daizo Tokinaga , Shuhei Yamamoto , Yoshiyuki Okishima , Masao Fukunaga , Takayasu Furukawa , Tomohiro Shoji
发明人: Yasushi Shimizu , Toshiaki Kita , Kiyoshi Tsukada , Akihiro Suzuki , Tomonari Morioka , Masaya Kojima , Ryoji Inaba , Daizo Tokinaga , Shuhei Yamamoto , Yoshiyuki Okishima , Masao Fukunaga , Takayasu Furukawa , Tomohiro Shoji
IPC分类号: C02F1/40
CPC分类号: G01N27/44721 , G01N27/44782
摘要: A capillary array includes a light detection portion, a sample supply portion, a buffer solution supply portion and a voltage application portion which are necessary functions for electrophoresis, thereby, when assembling the capillary array into an electrophoresis apparatus, the same can be immediately used. Accordingly, a capillary array is provided which can be easily incorporated into an electrophoresis apparatus.
摘要翻译: 毛细管阵列包括作为电泳所需功能的光检测部分,样品供应部分,缓冲溶液供应部分和电压施加部分,从而当将毛细管阵列组装到电泳装置中时可以立即使用。 因此,提供了可以容易地并入电泳装置中的毛细管阵列。
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公开(公告)号:US20060049053A1
公开(公告)日:2006-03-09
申请号:US11204116
申请日:2005-08-16
IPC分类号: C07K1/26 , G01N27/447
CPC分类号: G01N27/44782 , G01N27/44721
摘要: A capillary array includes multiple capillaries and two holding substrates for arranging the aforementioned multiple capillaries in a substantially plane surface by sandwiching at least some of these capillaries mutually. One of the holding substrates has a detection window for transmitting the detected light emitted by a test sample by irradiation of light. Especially, this detection window includes multiple light transmission areas provided to correspond to each capillary to transmit the detected light, and light cut-off areas provided between these light transmission areas to cut off the detected light. These light cut-off areas cut off light reflected from the surface of capillaries and hence improve the SN ratio, thereby ensuring high-precision detection.
摘要翻译: 毛细管阵列包括多个毛细管和两个保持基板,用于通过相互夹住这些毛细管中的至少一些来将上述多个毛细管布置在基本上平面的表面中。 保持基板中的一个具有用于通过照射光透射由测试样品发射的检测到的光的检测窗口。 特别地,该检测窗口包括多个透光区域,其设置为对应于每个毛细管以透射检测到的光,以及设置在这些光透射区域之间的遮光区域,以切断检测到的光。 这些遮光区域切断从毛细管表面反射的光,从而提高SN比,从而确保高精度检测。
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公开(公告)号:US07005052B2
公开(公告)日:2006-02-28
申请号:US09845303
申请日:2001-05-01
申请人: Yasushi Shimizu , Toshiaki Kita , Kiyoshi Tsukada , Akihiro Suzuki , Tomonari Morioka , Masaya Kojima , Ryoji Inaba , Daizo Tokinaga , Shuhei Yamamoto , Yoshiyuki Okishima , Masao Fukunaga , Takayasu Furukawa , Tomohiro Shoji
发明人: Yasushi Shimizu , Toshiaki Kita , Kiyoshi Tsukada , Akihiro Suzuki , Tomonari Morioka , Masaya Kojima , Ryoji Inaba , Daizo Tokinaga , Shuhei Yamamoto , Yoshiyuki Okishima , Masao Fukunaga , Takayasu Furukawa , Tomohiro Shoji
IPC分类号: G01N27/447 , C02F1/40
CPC分类号: G01N27/44721 , G01N27/44782
摘要: A capillary array includes a light detection portion, a sample supply portion, a buffer solution supply portion and a voltage application portion which are necessary functions for electrophoresis, thereby, when assembling the capillary array into an electrophoresis apparatus, the same can be immediately used. Accordingly, a capillary array is provided which can be easily incorporated into an electrophoresis apparatus.
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公开(公告)号:US07054004B2
公开(公告)日:2006-05-30
申请号:US10704827
申请日:2003-11-12
申请人: Ryoji Inaba , Toshiaki Kita , Miho Ozawa , Tomonari Morioka , Akihiro Suzuki , Yasushi Shimizu , Masaya Kojima
发明人: Ryoji Inaba , Toshiaki Kita , Miho Ozawa , Tomonari Morioka , Akihiro Suzuki , Yasushi Shimizu , Masaya Kojima
CPC分类号: G01N27/44721 , G01N27/44782
摘要: A multi-focus capillary array that can reduce crosstalk and a capillary array photodetector are provided. On a substrate 20 on which a plurality of capillaries are aligned, a perforation 72 is formed in at least a part of an area in the rear of the capillaries when the capillary array is viewed from the photodetector.
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