公开(公告)号：US20210106760A1

公开(公告)日：2021-04-15

申请号：US16497492

申请日：2018-03-13

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED ,  ARTE CORPORATION

Inventor： Atsushi KANAZAWA ,  Kiyotaka KAMATA ,  Akihiko ONO ,  Tomoyuki MANOSHIRO ,  Jiichi ARAI ,  Naoki CHODA

IPC: A61M5/31 ,  A61M5/315

Abstract: The present invention improves the feeling in use when a finger is hooked on a finger grip. This syringe is provided with a cylinder 22, a syringe needle 24, a finger grip 30, and a plunger rod 32. The finger grip 30 is provided with a cylindrical portion and a pair of finger hook portions. The finger hook portion has an inclined curved surface 70 and an end-side curved surface 72. The inclined curved surface 70 is disposed on a side, of a side surface of the finger hook portion, connected to the cylinder 22. In the inclined curved surface 70, the inclination of a base-side region with respect to the center axis of the cylindrical portion is gentler than the inclination of an end-side region with respect to the center axis of the cylindrical portion. The end-side curved surface 72 is disposed at the boundary between the end of the finger hook portion and the inclined curved surface 70. The end-side curved surface 72 extends along the boundary.

公开(公告)号：US20160310412A1

公开(公告)日：2016-10-27

申请号：US15104642

申请日：2014-12-15

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Inventor： Yutaka TANOUE ,  Yumiko ISHII ,  Yoshihiro OMACHI ,  Tomoyuki MANOSHIRO

IPC: A61K9/00 ,  A61K39/12 ,  A61K47/40 ,  A61K47/26 ,  A61K47/36 ,  A61K39/08 ,  C12N7/00

CPC classification number: A61K9/0021 ,  A61K39/08 ,  A61K39/12 ,  A61K47/26 ,  A61K47/36 ,  A61K47/40 ,  A61K2039/5258 ,  A61K2039/54 ,  C12N7/00 ,  C12N2770/16023 ,  C12N2770/16034 ,  Y02A50/386

Abstract: In order to configure a microneedle to be more suitable for administering a vaccine antigen, the present invention is a formulation having a dissolving-type microspike which is used as a microneedle in which a vaccine antigen is stabilized, and which includes a vaccine antigen, an ionic polymer base material, and at least one species selected from the group consisting of a non-reducing sugar, a sugar alcohol, cyclodextrin, and a surfactant.

Abstract translation: 为了将微针配置为更适合于施用疫苗抗原，本发明是具有溶解型小珠的制剂，其用作疫苗抗原稳定化的微针，其包含疫苗抗原， 离子聚合物基材，以及选自非还原糖，糖醇，环糊精和表面活性剂中的至少一种。