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    Systems and methods for personalized cardiovascular analyses
    2.
    发明授权
    Systems and methods for personalized cardiovascular analyses 有权

    公开(公告)号：US11837364B2

    公开(公告)日：2023-12-05

    申请号：US17118951

    申请日：2020-12-11

    申请人： TC1 LLC

    发明人： Eric Lee ,  Daniel I. Harjes

    IPC分类号： G16H50/00 ,  G16H40/67 ,  G16H10/60

    CPC分类号： G16H50/00 ,  G16H10/60 ,  G16H40/67

    摘要： Systems and methods for performing personalized cardiovascular analyses are provided. A method includes building, using a modeling and simulation computing device, a patient-specific model, storing, using the modeling and simulation computing device, the patient-specific model in a database, receiving, at the modeling and simulation computing device, remote monitoring data from at least one remote monitoring data source, and receiving, at the modeling and simulation computing device, clinical data from at least one clinical data source. The method further includes updating, using the modeling and simulation computing device, the patient-specific model using the remote monitoring data and the clinical data, performing, using the modeling and simulation computing device, at least one simulation on the updated patient-specific model, and outputting, from the modeling and simulation computing device, at least one output based on the at least one simulation.

    Pressure Sensing Ventricular Assist Devices and Methods of Use
    3.
    发明申请
    Pressure Sensing Ventricular Assist Devices and Methods of Use 有权

    公开(公告)号：US20210001025A1

    公开(公告)日：2021-01-07

    申请号：US17028687

    申请日：2020-09-22

    申请人： TC1 LLC

    发明人： Daniel I. Harjes ,  Kathryn B. Frederick ,  Eric Lee

    IPC分类号： A61M1/10 ,  A61B5/029 ,  A61M1/12 ,  A61B5/00

    摘要： The invention generally relates to heart pump systems. In some embodiments, a pressure sensor is provided with a heart pump, either at the inflow or the outflow of the blood pump. The heart pump may further include a flow estimator based on a rotor drive current signal delivered to the rotor. Based on the rotor drive current signal, a differential pressure across the pump may be calculated. The differential pressure in combination with the pressure measurements from the pressure sensor may be used to calculate pressure on the opposite side of the pump from the pressure sensor. In some embodiments, the pressure sensor is located at the outflow of the pump and the pump is coupled with the left ventricle. The differential pressure and pressure measurement may be used to calculate a left ventricular pressure waveform of the patient. With such a measurement, other physiological parameters may be derived.

    SYSTEMS AND METHODS FOR PERSONALIZED CARDIOVASCULAR ANALYSES
    5.
    发明申请
    SYSTEMS AND METHODS FOR PERSONALIZED CARDIOVASCULAR ANALYSES 有权

    公开(公告)号：US20210193315A1

    公开(公告)日：2021-06-24

    申请号：US17118951

    申请日：2020-12-11

    申请人： TC1 LLC

    发明人： Eric Lee ,  Daniel I. Harjes

    IPC分类号： G16H50/00 ,  G16H40/67 ,  G16H10/60

    摘要： Systems and methods for performing personalized cardiovascular analyses are provided. A method includes building, using a modeling and simulation computing device, a patient-specific model, storing, using the modeling and simulation computing device, the patient-specific model in a database, receiving, at the modeling and simulation computing device, remote monitoring data from at least one remote monitoring data source, and receiving, at the modeling and simulation computing device, clinical data from at least one clinical data source. The method further includes updating, using the modeling and simulation computing device, the patient-specific model using the remote monitoring data and the clinical data, performing, using the modeling and simulation computing device, at least one simulation on the updated patient-specific model, and outputting, from the modeling and simulation computing device, at least one output based on the at least one simulation.

    PRESSURE SENSING VENTRICULAR ASSIST DEVICES AND METHODS OF USE
    7.
    发明申请
    PRESSURE SENSING VENTRICULAR ASSIST DEVICES AND METHODS OF USE 审中-公开

    公开(公告)号：US20180280601A1

    公开(公告)日：2018-10-04

    申请号：US15939105

    申请日：2018-03-28

    申请人： TC1 LLC

    发明人： Daniel I. Harjes ,  Kathryn B. Frederick ,  Eric Lee

    IPC分类号： A61M1/10 ,  A61B5/029 ,  A61M1/12 ,  A61B5/00

    摘要： The invention generally relates to heart pump systems. In some embodiments, a pressure sensor is provided with a heart pump, either at the inflow or the outflow of the blood pump. The heart pump may further include a flow estimator based on a rotor drive current signal delivered to the rotor. Based on the rotor drive current signal, a differential pressure across the pump may be calculated. The differential pressure in combination with the pressure measurements from the pressure sensor may be used to calculate pressure on the opposite side of the pump from the pressure sensor. In some embodiments, the pressure sensor is located at the outflow of the pump and the pump is coupled with the left ventricle. The differential pressure and pressure measurement may be used to calculate a left ventricular pressure waveform of the patient. With such a measurement, other physiological parameters may be derived.