-
公开(公告)号：US11077069B2
公开(公告)日：2021-08-03
申请号：US15764422
申请日：2016-09-30
IPC分类号： A61K9/70 , A61K31/485 , A61K31/48 , A61K31/4468 , A61K31/4045 , A61K31/215 , A61K31/18 , A61K31/167 , A61K31/135 , A61K45/00 , A61K47/32 , C08F293/00 , C09J7/20 , A61K9/00
摘要： The present invention provides a star-shaped acrylic block polymer having a star-shaped structure in which at least three chain polymer portions radiate from a mercapto group situated at the center, wherein (meth)acrylic acid alkyl ester structural units having 7-17 carbon atoms account for 30-99.9% by mass of whole structural units of the star-shaped acrylic block polymer, and at least one of the chain polymer portions has a copolymer structure of polymerizable monomers containing a (meth)acrylic acid alkyl ester having 7-17 carbon atoms and a weakly basic monomer; and a medical patch containing an adhesive composition containing a salt of a basic drug and the star-shaped acrylic block polymer as an adhesive that exhibits high drug efficacy, that does not cause a decrease in adhesive property of an adhesive base due to an additive, and that causes less skin irritation.
-
公开(公告)号：US11382870B2
公开(公告)日：2022-07-12
申请号：US16500446
申请日：2018-04-04
IPC分类号： A61K9/70 , A61K47/32 , A61K47/12 , A61P25/18 , A61K47/14 , A61K31/194 , A61K31/20 , A61K31/519
摘要： The present invention provides a risperidone-containing patch having an excellent drug release property and patch physical properties. Specifically, the present invention provides a medical patch comprising an adhesive composition comprising risperidone or a pharmaceutically acceptable salt thereof; a carboxylic acid; a fatty acid ester; and an adhesive, characterized in that said adhesive is a star-shaped acrylic block polymer having a star-shaped structure in which at least three chain polymer portions radiate from a sulfur residue of a mercapto group situated at the center, wherein the (meth)acrylic acid alkyl ester structural units having 7-17 carbon atoms account for 30-99.99% by mass of the whole structural units in said star-shaped acrylic block polymer, and at least one of said chain polymer portions has a structural unit having a copolymer structure of polymerizable monomers comprising a (meth)acrylic acid alkyl ester having 7-17 carbon atoms and a polyfunctional monomer.
-
公开(公告)号：US10335389B2
公开(公告)日：2019-07-02
申请号：US14910738
申请日：2014-08-07
发明人： Satoshi Kawakami , Manabu Sogabe , Taiki Shibata
IPC分类号： A61K31/343 , A61K47/10 , A61K31/5585 , A61K47/02 , A61K47/12 , A61K9/70
摘要： The present invention provides a patch containing beraprost or a pharmacologically acceptable salt thereof, which achieves high transdermal absorption of beraprost or a pharmacologically acceptable salt thereof and has excellent formulation properties.
-
公开(公告)号：US10137098B2
公开(公告)日：2018-11-27
申请号：US15311670
申请日：2015-05-20
发明人： Satoshi Kawakami , Taiki Shibata , Manabu Sogabe
摘要： Provided is a novel transdermal absorption preparation containing silodosin or tamsulosin, or salt thereof as an active ingredient, wherein the transdermal absorption preparation is capable of keeping a dissolved state for a long time, as well as has a high permeability to a skin, and can effectively and sustainably exert the transdermal absorbability. A transdermal absorption preparation containing the transdermal absorption preparation comprises an acrylic pressure-sensitive adhesive that comprises a copolymer of at least one (meth)acrylic acid monomer and at least one vinyl monomer and that contains a carboxyl group, and at least one transdermal absorption promoting agent selected from the group consisting of oleyl alcohol, lauryl alcohol, and lauromacrogol.
-
公开(公告)号：US10195162B2
公开(公告)日：2019-02-05
申请号：US14368320
申请日：2012-12-25
发明人： Taiki Shibata , Kensuke Murata , Kenichi Hattori , Shinji Tanaka
IPC分类号： A61K9/70 , A61K31/70 , A61K31/137 , A61K31/7076 , A61K31/7084
摘要： The present invention provides a tolterodine-containing patch in which an adhesive layer is laminated on a backing, characterized in that the adhesive layer is obtainable by adding tolterodine to an adhesive base comprising a rubber adhesive, a tackifier resin, and a softener, wherein the tolterodine is present in the form of a free base in the adhesive base.
-
公开(公告)号：US20150017226A1
公开(公告)日：2015-01-15
申请号：US14368320
申请日：2012-12-25
发明人： Taiki Shibata , Kensuke Murata , Kenichi Hattori , Shinji Tanaka
IPC分类号： A61K31/137 , A61K9/70
CPC分类号： A61K31/137 , A61K9/7053 , A61K31/70 , A61K31/7076 , A61K31/7084
摘要： The present invention provides a tolterodine-containing patch in which an adhesive layer is laminated on a backing, characterized in that the adhesive layer is obtainable by adding tolterodine to an adhesive base comprising a rubber adhesive, a tackifier resin, and a softener, wherein the tolterodine is present in the form of a free base in the adhesive base.
摘要翻译： 本发明提供了一种含有托特罗定的贴剂，其中粘合剂层层压在背衬上，其特征在于，粘合剂层可通过向包含橡胶粘合剂，增粘树脂和软化剂的粘合剂基底添加托特罗定而得到，其中 托特罗定以粘合剂基质中游离碱的形式存在。
-
-
-
-
-
搜索结果
6 条记录 (耗时 0.016 秒)
