公开(公告)号：US20210208129A1

公开(公告)日：2021-07-08

申请号：US17054957

申请日：2019-05-13

Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM

Inventor： Brijesh S. Gill ,  Kevin R. Aroom ,  Charles S. Cox, Jr. ,  Tushar Sharma

IPC: G01N33/49 ,  B01L3/00

Abstract: An apparatus for determining the capacity of a blood sample to clot, the apparatus having a body with a cavity thereon to receive the blood sample, a displacement member movably received on the body and movable from a first position to a second position, a spring element for imparting a retaining force against movement of the displacement member from the first position, and a discrete indicator for generating a signal when the displacement member is moved to the second position. The coagulation and contraction of the blood sample as it clots adheres to and moves the displacement member from the first position towards the second position against the retaining force of the spring element. The indicator may include a mechanical switch, an exothermic chemical switch, a chemiluminescent chemical switch, a segmented optical pathway, an electrical switch, a field effect transistor switch or a Hall effect magnetic switch.

公开(公告)号：US10669516B2

公开(公告)日：2020-06-02

申请号：US15738257

申请日：2016-06-23

Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM

Inventor： Charles S. Cox, Jr. ,  Brijesh S. Gill ,  Kevin Aroom ,  Pamela Wenzel

IPC: C12M1/12 ,  C12M3/00 ,  C12M1/42 ,  A61K35/28 ,  C12N5/0775 ,  C12M1/00 ,  A61P25/00

Abstract: A bioreactor system for conditioning of pluripotent cells or cell media is provided. In further aspects, conditioned pluripotent cells and methods for making such cells are provided.

公开(公告)号：US11162063B2

公开(公告)日：2021-11-02

申请号：US16855831

申请日：2020-04-22

Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM

Inventor： Charles S. Cox, Jr. ,  Brijesh S. Gill ,  Kevin Aroom ,  Pamela Wenzel

IPC: C12M1/42 ,  C12M1/12 ,  C12M1/00 ,  C12M3/00 ,  A61K35/28 ,  C12N5/0775 ,  A61P25/00

Abstract: A bioreactor system for conditioning of pluripotent cells or cell media is provided. In further aspects, conditioned pluripotent cells and methods for making such cells are provided.

公开(公告)号：US10960029B2

公开(公告)日：2021-03-30

申请号：US15449085

申请日：2017-03-03

Applicant: The Board of Regents of the University of Texas System

Inventor： Charles S. Cox, Jr. ,  Brijesh S. Gill ,  Kevin Aroom ,  Tushar Sharma

IPC: A61K35/51 ,  A61B17/12 ,  A61F2/46 ,  B26B3/00 ,  B26D1/06 ,  B30B9/20 ,  C12N5/073 ,  A61B5/15

Abstract: Devices and methods for extraction and processing of substantia gelatinea funiculi umbilicalis (Wharton's Jelly) from an umbilical cord. Isolated pluripotent cell compositions and methods of using the same are also provided.