-
公开(公告)号:US20210317406A1
公开(公告)日:2021-10-14
申请号:US17259085
申请日:2019-07-09
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor: Alexander MARSON , Eric SHIFRUT , Julia CARNEVALE , Alan ASHWORTH
IPC: C12N5/0783 , A61K35/17 , C12N15/11 , C12N15/113 , C12N9/22
Abstract: Provided herein are genetically modified T cells that exhibit increased proliferation compared to wild-type T cells when stimulated, methods of generating such T cells, and methods of using the T cells for the treatment of a disease such as cancer.