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1.发明申请公开(公告)号：US20220212036A1
公开(公告)日：2022-07-07
申请号：US17600564
申请日：2020-05-11
Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
Inventor： Issam El Naqa , Xueding Wang , Paul Carson , Kyle Cuneo , Jean Moran , Wei Zhang , Ibrahim Oraiqat
Abstract: A method and system for performing online adapted radiotherapy are provided using combined ultrasound and ionizing radiation induced acoustic imaging (iRAI) computed tomography imaging techniques that can be used for measurement of low to ultrahigh dose deliveries (>40 Gy/s). Multiplexed transducers detect US and iRAI signals allowing for anatomical/functional imaging and radiation mapping with absolute dosimetry measurements of a region of interest during a radiotherapy session. Corrections to radiation dosage intensities and locations is determined and provided as feedback to a radiation source to improve the accuracy of applied radiation dosages intra- or inter-radiotherapy treatment sessions preventing the irradiation of healthy tissues and ensuring the accurate delivery of radiation to a tumor or region of interest.
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2.发明申请公开(公告)号：US20250001211A1
公开(公告)日：2025-01-02
申请号：US18883578
申请日：2024-09-12
Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
Inventor： Issam El Naqa , Xueding Wang , Paul Carson , Kyle Cuneo , Jean Moran , Wei Zhang , Ibrahim Oraiqat
Abstract: A method and system for performing online adapted radiotherapy are provided using combined ultrasound and ionizing radiation induced acoustic imaging (iRAI) computed tomography imaging techniques that can be used for measurement of low to ultrahigh dose deliveries (>40 Gy/s). Multiplexed transducers detect US and iRAI signals allowing for anatomical/functional imaging and radiation mapping with absolute dosimetry measurements of a region of interest during a radiotherapy session. Corrections to radiation dosage intensities and locations is determined and provided as feedback to a radiation source to improve the accuracy of applied radiation dosages intra- or inter-radiotherapy treatment sessions preventing the irradiation of healthy tissues and ensuring the accurate delivery of radiation to a tumor or region of interest.
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3.发明授权公开(公告)号：US12102843B2
公开(公告)日：2024-10-01
申请号：US17600564
申请日：2020-05-11
Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
Inventor： Issam El Naqa , Xueding Wang , Paul Carson , Kyle Cuneo , Jean Moran , Wei Zhang , Ibrahim Oraiqat
CPC classification number: A61N5/1067 , A61B8/08 , A61B8/485 , A61N5/1038 , A61N5/1039 , A61N5/1049 , A61N5/1071 , A61N2005/1054 , A61N2005/1058
Abstract: A method and system for performing online adapted radiotherapy are provided using combined ultrasound and ionizing radiation induced acoustic imaging (iRAI) computed tomography imaging techniques that can be used for measurement of low to ultrahigh dose deliveries (>40 Gy/s). Multiplexed transducers detect US and iRAI signals allowing for anatomical/functional imaging and radiation mapping with absolute dosimetry measurements of a region of interest during a radiotherapy session. Corrections to radiation dosage intensities and locations is determined and provided as feedback to a radiation source to improve the accuracy of applied radiation dosages intra- or inter-radiotherapy treatment sessions preventing the irradiation of healthy tissues and ensuring the accurate delivery of radiation to a tumor or region of interest.
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