公开(公告)号：US11384391B2

公开(公告)日：2022-07-12

申请号：US16091442

申请日：2017-04-04

Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

Inventor： Jingyue Ju ,  Shiv Kumar ,  James J. Russo ,  Steffen Jockusch ,  Zengmin Li ,  Xiaoxu Li ,  Sergey M. Kalachikov ,  Irina Morozova

IPC: C12Q1/68 ,  C07H19/10 ,  C07H19/20 ,  C12Q1/6869

Abstract: This invention provides nucleotide analogues each of which comprises a tag comprising one or more Forster resonance energy transfer (FRET) acceptor fluorophores, a nucleotide polymerase having one or more FRET donor fluorophores, and methods for sequencing single-stranded.

公开(公告)号：US20220364167A1

公开(公告)日：2022-11-17

申请号：US17860036

申请日：2022-07-07

Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

Inventor： Jingyue Ju ,  Shiv Kumar ,  James J. Russo ,  Steffen Jockusch ,  Zengmin Li ,  Xiaoxu Li ,  Sergey M. Kalachikov ,  Irina Morozova

IPC: C12Q1/6869 ,  C07H19/10 ,  C07H19/20

Abstract: This invention provides nucleotide analogues each of which comprises a tag comprising one or more Forster resonance energy transfer (FRET) acceptor fluorophores, a nucleotide polymerase having one or more FRET donor fluorophores, and methods for sequencing single-stranded

公开(公告)号：US20190153527A1

公开(公告)日：2019-05-23

申请号：US16091442

申请日：2017-04-04

Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

Inventor： Jingyue Ju ,  Shiv Kumar ,  James J. Russo ,  Steffen Jockusch ,  Zengmin Li ,  Xiaoxu Li ,  Sergey M. Kalachikov ,  Irina Morozova

IPC: C12Q1/6869 ,  C07H19/10 ,  C07H19/20

Abstract: This invention provides nucleotide analogues each of which comprises a tag comprising one or more Forster resonance energy transfer (FRET) acceptor fluorophores, a nucleotide polymerase having one or more FRET donor fluorophores, and methods for sequencing single-stranded